Results 141 to 150 of about 2,154,958 (312)
When conventional procedures are no longer the rule for application: design as a discipline opens up to new possibilities [PDF]
, 2009 This paper discusses the development of the prototype application ‘LabanAssist’. It looks at the design rationale used for the creation of what is fundamentally a system for recording dance knowledge on a score, as identifiable and replicable signs and ...
Ebenreuter, Natalie
core
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Design thinking na publicidade
Comunicação & Educação, 2019 Neste artigo, apresentamos uma proposta de ensino-aprendizagem para o desenvolvimento de projetos publicitários com design thinking (DT), considerando como público-alvo estudantes de graduação em Publicidade e Propaganda.
Amarinildo Osório de Souza +1 more
doaj
REDESIGN USER INTERFACE APLIKASI NGAJI.AI BERBASIS MOBILE MENGGUNAKAN METODE DESIGN THINKING [PDF]
Ngaji.AI is a mobile-based application that makes it possible to learn the Koran very flexibly, wherever and whenever we can use it to learn the Koran.
Aldiensyah, Aldiensyah
core
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Think Software Think Testing Think Design
International Journal of Computer Sciences and Engineering, 2019 Sushmitha S Prabhu, Zoya Kapoor
openaire +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Journal of Danubian Studies and Research, 2016 The article clarifies the pedagogical content of the notion “design”, which is seen as a kind of creative activity, aimed at creating comfortable and aesthetically expressive of the subject environment, which most fully meets the aesthetic and ...
Kholostenko Y.V.
doaj
Innovative Design Thinking of the Designer As Pedagogical Problem
, 2019 T.E. Belyakova, I.N. Sizova
openalex +1 more source