Results 41 to 50 of about 361,254 (315)

Genomic Diversity and Clinical Variability in Pediatric Primary Cutaneous Anaplastic Large Cell Lymphoma: A Case Series

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger   +7 more
wiley   +1 more source

The Nature of Design Thinking [PDF]

open access: yes, 2010
In the last few years, 'Design Thinking' has gained popularity - it is now seen as an exciting new paradigm for dealing with problems in sectors as a far afield as IT, Business, Education and Medicine.
Kees Dorst, Dorst, K
core  

Four Criteria for Design Theories

open access: yesShe Ji: The Journal of Design, Economics and Innovation
The goal of this paper is to demonstrate that the adoption of the four criteria we outline will strengthen future design theories and encourage existing design theories to expand or reconfigure in useful directions.
Peter Hodges   +5 more
doaj   +1 more source

DESIGN-BASED THINKING METHOD IN BUSINESS MANAGEMENT

open access: yesNowoczesne Systemy Zarządzania, 2020
Rapid technological development, geographically unrestricted markets, offer customers great opportunities to meet their needs when choosing and purchasing products or services, and companies need to use new and creative methods such as design-based ...
Daiva Žostautienė   +2 more
doaj   +1 more source

Time course of eccentric macular hole formation after pars plana vitrectomy for epiretinal membrane detected by optical coherence tomography

open access: yesAmerican Journal of Ophthalmology Case Reports, 2023
Purpose: This case report aims to describe the detailed time course of eccentric macular hole (MH) formation following pars plana vitrectomy (PPV) for epiretinal membrane (ERM) treatment, using optical coherence tomography (OCT) images.
Masahiro Akada, Hitoshi Tabuchi
doaj   +1 more source

Central Nervous System Neuroblastoma, FOXR2‐Activated: A Pooled Analysis of Published Clinical Outcomes

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan   +1 more
wiley   +1 more source

Design thinking pedagogy: The educational design ladder [PDF]

open access: yes, 2015
As global industries change and technology advances, traditional education systems might no longer be able to supply companies with graduates who possess an appropriate mix of skills and experience.
Wrigley, Cara, Straker, Karla
core   +1 more source

Computational Thinking and Modeling: A Quasi-Experimental Study of Learning Transfer

open access: yesEducation Sciences
This quasi-experimental study investigated the impact of computational learning activities on high school students’ computational thinking (CT) and computational modeling (CM) skills.
Line Have Musaeus, Peter Musaeus
doaj   +1 more source

Creative integration of design thinking and strategic thinking in a design education framework

open access: yesCreativity Studies, 2021
With rapid globalization, designers are increasingly required to use creative integration of strategic thinking and design thinking to deal with complexity and uncertainty in an era of constant transformation.
Woonghee Park, Hyun-Kyung Lee
doaj   +1 more source

Feasibility and Safety of Somato‐Cognitive Coordination Therapy for Cerebellar Ataxia Following Pediatric Brain Tumor Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cerebellar ataxia after pediatric brain tumor treatment can cause persistent gait, balance, and speech impairment, yet no established rehabilitation strategy exists. Somato‐cognitive coordination therapy (SCCT) is a virtual reality–guided intervention designed to promote sensorimotor integration through visually constrained reaching
Masanobu Takeuchi   +10 more
wiley   +1 more source

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