Results 21 to 30 of about 121,553 (350)

Thalamic inputs to dorsomedial striatum are involved in inhibitory control: evidence from the five-choice serial reaction time task in rats [PDF]

, 2017
Rationale Corticostriatal circuits are widely implicated in the top-down control of attention including inhibitory control and behavioural flexibility. However, recent neurophysiological evidence also suggests a role for thalamic inputs to striatum in
A Bari, A Castañé, BN Armbruster, D Dautan, EA Schilman, ER Murphy, ES Robinson, G Paxinos, GM Alexander, HD Brown, J Groenewegen, J Wess, JN Rouder, JW Dalley, K Guillem, KM Turner, LA Bradfield, M Baviera, M Bentivoglio, M Carli, M Kimura, M Pezze, ME Ragozzino, N Amitai, N Matsumoto, NM Doig, P Aldrin-Kirk, RD Rogers, S Kinomura, SV Mahler, T Minamimoto, T Robbins, TJ Stachniak, TW Faust, V Boulougouris, Y Chudasama, Y Smith   +36 more
core   +2 more sources

Conditioned stimulus effects on paired or alternative reinforcement depend on presentation duration: Implications for conceptualizations of craving

Frontiers in Behavioral Neuroscience, 2022
Conditioned stimuli (CS) associated with alcohol ingestion are thought to play a role in relapse by producing a craving that in turn increases motivation to drink which increases ethanol-seeking and disrupts other ongoing behavior. Alternatively, such CS
Brett C. Ginsburg, Acacia Nawrocik-Madrid, Charles W. Schindler, R. J. Lamb   +3 more
doaj   +1 more source

Death following recreational use of designer drug "bath salts" containing 3,4-Methylenedioxypyrovalerone (MDPV). [PDF]

J Med Toxicol, 2012
Murray BL, Murphy CM, Beuhler MC.
europepmc   +3 more sources

Recreational use, analysis and toxicity of tryptamines [PDF]

, 2015
The definition New psychoactive substances (NPS) refers to emerging drugs whose chemical structures are similar to other psychoactive compounds but not identical, representing a "legal" alternative to internationally controlled drugs.
Mannocchi, Giulio, Pantano, Flaminia, Romolo, Francesco Saverio, Tittarelli, Roberta   +3 more
core   +1 more source

Novel Designer Benzodiazepines: Comprehensive Review of Evolving Clinical and Adverse Effects

Neurology International, 2022
As tranquilizers, benzodiazepines have a wide range of clinical uses. Recently, there has been a significant rise in the number of novel psychoactive substances, including designer benzodiazepines.
Amber N. Edinoff, Catherine A. Nix, Amira S. Odisho, Caroline P. Babin, Alyssa G. Derouen, Salim C. Lutfallah, Elyse M. Cornett, Kevin S. Murnane, Adam M. Kaye, Alan D. Kaye   +9 more
doaj   +1 more source

Detection of Drugs of Abuse by Raman Spectroscopy [PDF]

, 2011
Raman spectroscopy can provide rapid, sensitive, non-destructive analysis of a variety of drug types (e.g. amphetamines, alkaloids, designer drugs and date rape drugs). This review concentrates on developments in the past 15 years.
Ali, Ali, Ali, Angel, Anyu, Bell, Bell, Bell, Bell, Bell, Brewster, Campion, Carter, Clark, Day, Day, Edwards, Eliasson, Faulds, Frederick, Garrido, Hargreaves, Hargreaves, Harvey, Katainen, Leger, Littleford, Milhazes, Milhazes, Noonan, Noonan, Qu, Ryder, Ryder, Ryder, Sands, Schulz, Smith, Sägmüller, Thorley, Tsuchihashi, West, West, West, Weston, White   +45 more
core   +1 more source

Designer receptor technology for the treatment of epilepsy

EBioMedicine, 2019
Epilepsy remains refractory to medical treatment in ~30% of patients despite decades of new drug development. Neurosurgery to remove or disconnect the seizure focus is often curative but frequently contraindicated by risks of irreversible impairment to ...
Andreas Lieb, Mikail Weston, Dimitri M. Kullmann   +2 more
doaj   +1 more source

Putting forward a model for the role of the cerebellum in cocaine-induced pavlovian memory

Frontiers in Systems Neuroscience, 2023
Substance Use Disorder (SUD) involves emotional, cognitive, and motivational dysfunction. Long-lasting molecular and structural changes in brain regions functionally and anatomically linked to the cerebellum, such as the prefrontal cortex, amygdala ...
Ignasi Melchor-Eixea, Julian Guarque-Chabrera, Aitor Sanchez-Hernandez, Patricia Ibáñez-Marín, Raúl Pastor, Marta Miquel   +5 more
doaj   +1 more source

25C-NBOMe: preliminary data on pharmacology, psychoactive effects, and toxicity of a new potent and dangerous hallucinogenic drug [PDF]

, 2014
Introduction. The use of novel psychoactive substances (NPSs) has rapidly increased as well as their online availability. The aim of this paper is to provide a comprehensive review of the nature and the risks associated with 25C-NBOMe, which has recently
BERSANI, FRANCESCO SAVERIO, BERSANI, Giuseppe, Eduardo Cinosi, Fabrizio Schifano, Flaminia Bolzan Mariotti Posocco, Gabriella Albano, Giovanni Martinotti, Giuseppe Valeriani, Ornella Corazza, Pierluigi Simonato, Rita Santacroce   +10 more
core   +5 more sources

2-(4-IODO-2,5-DIMETOXIFENIL)-N-[(2-METOXIFENIL)METIL]ETAMINA OU 25I-NBOME: CARACTERIZAÇÃO QUÍMICA DE UMA DESIGNER DRUG

Química Nova, 2016
Drug trafficking and the introduction of new drugs onto the illicit market are one of the main challenges of the forensic community. In this study, the chemical profile of a new designer drug, 2-(4-iodine-2,5-dimethoxyphenyl)-n-[(2-methoxyphenyl)methyl ...
Pâmella F. dos Santos, Lindamara M. Souza, Bianca B. Merlo, Helber B. Costa, Lilian V. Tose, Heloá Santos, Gabriela Vanini, Leandro F. Machado, Rafael S. Ortiz, Renata P. Limberger, Boniek G. Vaz, Wanderson Romão   +11 more
doaj   +1 more source