Results 21 to 30 of about 4,227,388 (391)
Naphthalen-1-yl-(1-pentylindol-3-yl)methanone (JWH-018) is a synthetic compound found in psychoactive “spice” products that activates cannabinoid receptors.
Joshua S. Elmore, Michael H. Baumann
doaj +1 more source
Identification of New Designer Benzodiazepine Diclazepam in Drug Facilitated Sexual Assault [PDF]
Objective To identify the new designer drugs which are totally unknown and not in the routine testing list by the technologies such as high-resolution mass spectrometry in drug facilitated sexual assault, in order to solve the problem in actual cases ...
XIANG Ping, SHEN Bao-hua, YAN Hui, et al
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Summary: Spinal cord injury (SCI) often results in spasticity. There is currently no effective therapy for spasticity. Here, we describe a method to efficiently differentiate human pluripotent stem cells from spinal GABA neurons.
ChenZi Gong +17 more
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Tools for Controlling Activity of Neural Circuits Can Boost Gastrointestinal Research [PDF]
We thank Prof U. G. Knaus and T. C. Collin for critical reading of the manuscript. GA is supported by the European Crohn's and Colitis Organization (ECCO) (J/15/2) and by the National Childrens' Research Centre (K/12/1). GD is supported by the University
Aviello, Gabriella, D'Agostino, Giuseppe
core +3 more sources
Recreational use, analysis and toxicity of tryptamines [PDF]
The definition New psychoactive substances (NPS) refers to emerging drugs whose chemical structures are similar to other psychoactive compounds but not identical, representing a "legal" alternative to internationally controlled drugs.
Mannocchi, Giulio +3 more
core +1 more source
Monitoring risk behaviour in adolescent pupils regarding consumption of psychoactive substances
Introduction Taking psychoactive substances constitutes a significant problem for Public Health, particularly in preventing drug abuse and addiction. Objectives To estimate the amount and incidence of drug consumption in middle and high school pupils ...
Paulina Wojtyła-Buciora +8 more
doaj +1 more source
Thalamic inputs to dorsomedial striatum are involved in inhibitory control: evidence from the five-choice serial reaction time task in rats [PDF]
Rationale Corticostriatal circuits are widely implicated in the top-down control of attention including inhibitory control and behavioural flexibility. However, recent neurophysiological evidence also suggests a role for thalamic inputs to striatum in
A Bari +36 more
core +2 more sources
Interneuron loss/dysfunction contributes to spontaneous recurrent seizures (SRS) in chronic temporal lobe epilepsy (TLE), and interneuron grafting into the epileptic hippocampus reduces SRS and improves cognitive function. This study investigated whether
Dinesh Upadhya +8 more
doaj +1 more source
Designer antiandrogens join the race against drug resistance
By using in silico models of the complexes formed by analogues of a cancer drug and its receptor, it may be possible to strategically redesign existing drugs and win the race against mutations that lead to drug resistance in prostate cancer.
Jatinder S Josan +1 more
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To avoid criminal prosecution, clandestine chemists produce designer stimulants that mimic the pharmacological and psychoactive effects of conventional stimulants, such as methamphetamine.
Nicole Hall +9 more
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