Results 1 to 10 of about 93,845 (280)

Identificação química da clorofenilpiperazina (CPP) em comprimidos apreendidos Chemical identification of chlorophenylpiperazine in seized tablets [PDF]

open access: yesQuímica Nova, 2010
Designer drug is a term used to describe psychoactive drugs of abuse which are usually synthesized by modifying the molecular structures of existing drugs of abuse.
Rafael Lanaro   +3 more
doaj   +4 more sources

High-potency ligands for DREADD imaging and activation in rodents and monkeys [PDF]

open access: yesNature Communications, 2019
Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) are a powerful tool for neuroscience, but the standard DREADD ligand, CNO, has significant drawbacks.
Jordi Bonaventura   +24 more
doaj   +2 more sources

Occurrence of Takotsubo Cardiomyopathy after Synthetic Cannabinoid Consumption [PDF]

open access: yesAddiction and Health, 2019
Background: Synthetic cannabinoid use such as “K2” and “Spice” is popular secondary to its inability to be detected in a urine drug screen. It is associated with a wide range of myocardial pathologies including obstructive and non-obstructive coronary ...
Denelle Mohammed
doaj   +1 more source

The DREADDful Hurdles and Opportunities of the Chronic Chemogenetic Toolbox

open access: yesCells, 2022
The chronic character of chemogenetics has been put forward as one of the assets of the technique, particularly in comparison to optogenetics. Yet, the vast majority of chemogenetic studies have focused on acute applications, while repeated, long-term ...
Marie Claes, Lies De Groef, Lieve Moons
doaj   +1 more source

Oneiroid catatonia due to the usage of spice: The case study

open access: yesEuropean Psychiatry, 2021
Introduction Designer drugs, as a term, first came about in the 1980s. Most of these “designer drugs” have synthetic cannabinoids and other psychoactive formulas difficulty to detect. Objectives A 28 year man was referred to the hospital.
O. Pityk   +4 more
doaj   +1 more source

Determination of dimethoxyphenethylamine derivatives in urine by deuterium labeled internal standards [PDF]

open access: yesJournal of the Serbian Chemical Society, 2008
The use of gas chromatography–mass spectrometry (GC–MS) in forensic analysis is increasing. To exploit fully the capabilities of MS, labeled standards, that can be used to improve the performance of the quantitative analysis, and to increase accuracy and
YA-ZHU XU   +3 more
doaj   +3 more sources

Wytwarzanie lub obrót dopalaczami jako czyn z art. 165 § 1 pkt 2 k.k.

open access: yesActa Iuris Stetinensis, 2018
The article discusses the issues of possibility to qualify producing or marketing the designer drugs as an offence form article 165 § 1 point 2 cc. The analysis is subjected primarily to ratio legis of this regulation, which shows that it does not have ...
Magdalena Kowalewska-Łukuć
doaj   +1 more source

Targeted Delivery of Chemogenetic Adeno-Associated Viral Vectors to Cortical Sulcus Regions in Macaque Monkeys by Handheld Injections

open access: yesBio-Protocol, 2023
Recent advancements in chemogenetic tools, such as designer receptors exclusively activated by designer drugs (DREADDs), allow the simultaneous manipulation of activity over a specific, broad brain region in nonhuman primates.
Kei Oyama   +2 more
doaj   +1 more source

Detection of Drugs of Abuse by Raman Spectroscopy [PDF]

open access: yes, 2011
Raman spectroscopy can provide rapid, sensitive, non-destructive analysis of a variety of drug types (e.g. amphetamines, alkaloids, designer drugs and date rape drugs). This review concentrates on developments in the past 15 years.
Ali   +45 more
core   +1 more source

Designer drugs: aspectos analíticos e biológicos

open access: yesQuímica Nova, 2012
In the recent years, analytical toxicologists have been facing difficulties in detecting designer drugs due to the chemical modifications on the existing structures and the speed in which they are released into the market, requiring the development and ...
Rachel Bulcão   +7 more
doaj   +1 more source

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