Results 21 to 30 of about 16,330 (302)
Inventions, 2023 The aim of this research was to develop and deploy efficient deep convolutional neural network (DCNN) frameworks for detecting and discriminating between various categories of designer drugs. These are of particular relevance in forensic contexts, aiding
Catalina Mercedes Burlacu +3 more
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Sequence-based drug design as a concept in computational drug design
Nature Communications, 2023 AbstractDrug development based on target proteins has been a successful approach in recent decades. However, the conventional structure-based drug design (SBDD) pipeline is a complex, human-engineered process with multiple independently optimized steps.
Lifan Chen +23 more
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Rational Drug Design Paradigms: The Odyssey for Designing Better Drugs
Combinatorial Chemistry & High Throughput Screening, 2015 Due to the time and effort requirements for the development of a new drug, and the high attrition rates associated with this developmental process, there is an intense effort by academic and industrial researchers to find novel ways for more effective drug development schemes.
Kellici T +13 more
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Pharmacology of amphetamine-type designer drugs [PDF]
, 2013 In this thesis project, we studied the pharmacology of long-known psychostimulants and of novel amphetamine-type designer drugs in vitro. On the basis of the pharmacological characterization, we focused on the drug effects in humans, investigating the ...
Simmler, Linda
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Acta Iuris Stetinensis, 2018 In view of the very serious social problem of designer drugs, which is growing with every passing day, we must take resolute and effective action as quickly as possible.
Piotr Jóźwiak
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Drugs in therapy. LSD, MDMA, marijuana, psilocybin, designer drugs and its potential in modern medicine. [PDF]
Farmacja Polska, 2020 Research on using drugs in medicine was almost completely stopped and delegalized in 1971, by Convention on Psychotropic Substances. Most of studies carried out before 1971 were methodologically inappropriate according to current research methodologies ...
Agata Tadeja
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Bio-Protocol, 2023 Recent advancements in chemogenetic tools, such as designer receptors exclusively activated by designer drugs (DREADDs), allow the simultaneous manipulation of activity over a specific, broad brain region in nonhuman primates.
Kei Oyama +2 more
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Between designer drugs and afterburners: A Lexicographic-Semantic Study of Equivalence
Lexikos, 2021 The lexicons of natural languages are not isomorphic. Reasons for the anisomorphism can be sought on three interrelated planes: language structure, extralinguistic reality, and conceptualisation.
Arleta Adamska-Sałaciak
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Química Nova, 2010 Designer drug is a term used to describe psychoactive drugs of abuse which are usually synthesized by modifying the molecular structures of existing drugs of abuse.
Rafael Lanaro +3 more
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Acta Iuris Stetinensis, 2018 The goal of this work is to answer a question if the regulations of art. 160 § 1–3 k.k. could be used in combating designer drugs. The findings of this work are based on: 1) analysis of the normative materials referring to the examined issue; and – 2 ...
Konrad Burdziak
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