Results 21 to 30 of about 16,272 (302)

Clinical profile of designer drug “Strox” intoxicated cases presented to Poison control center Ain Shams University, Egypt from first of January 2017 to end of January 2018 [PDF]

open access: yesAin Shams Journal of Forensic Medicine and Clinical Toxicology, 2021
Introduction: Drug addiction is considered one of the serious problems. Clinical profile of drug dependence is continuously changing taking new shape, new drugs and routes.
Salma Abdelkader, Mohy El-Masry
doaj   +1 more source

Occurrence of Takotsubo Cardiomyopathy after Synthetic Cannabinoid Consumption [PDF]

open access: yesAddiction and Health, 2019
Background: Synthetic cannabinoid use such as “K2” and “Spice” is popular secondary to its inability to be detected in a urine drug screen. It is associated with a wide range of myocardial pathologies including obstructive and non-obstructive coronary ...
Denelle Mohammed
doaj   +1 more source

The DREADDful Hurdles and Opportunities of the Chronic Chemogenetic Toolbox

open access: yesCells, 2022
The chronic character of chemogenetics has been put forward as one of the assets of the technique, particularly in comparison to optogenetics. Yet, the vast majority of chemogenetic studies have focused on acute applications, while repeated, long-term ...
Marie Claes, Lies De Groef, Lieve Moons
doaj   +1 more source

Combining designer receptors exclusively activated by designer drugs and neuroimaging in experimental models: A powerful approach towards neurotheranostic applications. [PDF]

open access: yesBr J Pharmacol, 2020
: The combination of chemogenetics targeting specific brain cell populations with in vivo imaging techniques provides scientists with a powerful new tool to study functional neural networks at the whole-brain scale.
Peeters LM   +3 more
europepmc   +2 more sources

Oneiroid catatonia due to the usage of spice: The case study

open access: yesEuropean Psychiatry, 2021
Introduction Designer drugs, as a term, first came about in the 1980s. Most of these “designer drugs” have synthetic cannabinoids and other psychoactive formulas difficulty to detect. Objectives A 28 year man was referred to the hospital.
O. Pityk   +4 more
doaj   +1 more source

Determination of dimethoxyphenethylamine derivatives in urine by deuterium labeled internal standards [PDF]

open access: yesJournal of the Serbian Chemical Society, 2008
The use of gas chromatography–mass spectrometry (GC–MS) in forensic analysis is increasing. To exploit fully the capabilities of MS, labeled standards, that can be used to improve the performance of the quantitative analysis, and to increase accuracy and
YA-ZHU XU   +3 more
doaj   +3 more sources

„Dopalacze” – nieprzewidywalne narkotyki. Problem społeczno-prawny

open access: yesFilozofia Publiczna i Edukacja Demokratyczna, 2019
The aim of this article is to present the problem of new psy­choactive substances – designer drugs. New drugs are undoubt­edly a social and legal problem.
Sebastian Matyjek
doaj   +1 more source

Targeted Delivery of Chemogenetic Adeno-Associated Viral Vectors to Cortical Sulcus Regions in Macaque Monkeys by Handheld Injections

open access: yesBio-Protocol, 2023
Recent advancements in chemogenetic tools, such as designer receptors exclusively activated by designer drugs (DREADDs), allow the simultaneous manipulation of activity over a specific, broad brain region in nonhuman primates.
Kei Oyama   +2 more
doaj   +1 more source

Sequence-based drug design as a concept in computational drug design

open access: yesNature Communications, 2023
AbstractDrug development based on target proteins has been a successful approach in recent decades. However, the conventional structure-based drug design (SBDD) pipeline is a complex, human-engineered process with multiple independently optimized steps.
Lifan Chen   +23 more
openaire   +3 more sources

Wytwarzanie lub obrót dopalaczami jako czyn z art. 165 § 1 pkt 2 k.k.

open access: yesActa Iuris Stetinensis, 2018
The article discusses the issues of possibility to qualify producing or marketing the designer drugs as an offence form article 165 § 1 point 2 cc. The analysis is subjected primarily to ratio legis of this regulation, which shows that it does not have ...
Magdalena Kowalewska-Łukuć
doaj   +1 more source

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