Clinical profile of designer drug “Strox” intoxicated cases presented to Poison control center Ain Shams University, Egypt from first of January 2017 to end of January 2018 [PDF]
Introduction: Drug addiction is considered one of the serious problems. Clinical profile of drug dependence is continuously changing taking new shape, new drugs and routes.
Salma Abdelkader, Mohy El-Masry
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Occurrence of Takotsubo Cardiomyopathy after Synthetic Cannabinoid Consumption [PDF]
Background: Synthetic cannabinoid use such as “K2” and “Spice” is popular secondary to its inability to be detected in a urine drug screen. It is associated with a wide range of myocardial pathologies including obstructive and non-obstructive coronary ...
Denelle Mohammed
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The DREADDful Hurdles and Opportunities of the Chronic Chemogenetic Toolbox
The chronic character of chemogenetics has been put forward as one of the assets of the technique, particularly in comparison to optogenetics. Yet, the vast majority of chemogenetic studies have focused on acute applications, while repeated, long-term ...
Marie Claes, Lies De Groef, Lieve Moons
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Combining designer receptors exclusively activated by designer drugs and neuroimaging in experimental models: A powerful approach towards neurotheranostic applications. [PDF]
: The combination of chemogenetics targeting specific brain cell populations with in vivo imaging techniques provides scientists with a powerful new tool to study functional neural networks at the whole-brain scale.
Peeters LM +3 more
europepmc +2 more sources
Oneiroid catatonia due to the usage of spice: The case study
Introduction Designer drugs, as a term, first came about in the 1980s. Most of these “designer drugs” have synthetic cannabinoids and other psychoactive formulas difficulty to detect. Objectives A 28 year man was referred to the hospital.
O. Pityk +4 more
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Determination of dimethoxyphenethylamine derivatives in urine by deuterium labeled internal standards [PDF]
The use of gas chromatography–mass spectrometry (GC–MS) in forensic analysis is increasing. To exploit fully the capabilities of MS, labeled standards, that can be used to improve the performance of the quantitative analysis, and to increase accuracy and
YA-ZHU XU +3 more
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„Dopalacze” – nieprzewidywalne narkotyki. Problem społeczno-prawny
The aim of this article is to present the problem of new psychoactive substances – designer drugs. New drugs are undoubtedly a social and legal problem.
Sebastian Matyjek
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Recent advancements in chemogenetic tools, such as designer receptors exclusively activated by designer drugs (DREADDs), allow the simultaneous manipulation of activity over a specific, broad brain region in nonhuman primates.
Kei Oyama +2 more
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Sequence-based drug design as a concept in computational drug design
AbstractDrug development based on target proteins has been a successful approach in recent decades. However, the conventional structure-based drug design (SBDD) pipeline is a complex, human-engineered process with multiple independently optimized steps.
Lifan Chen +23 more
openaire +3 more sources
Wytwarzanie lub obrót dopalaczami jako czyn z art. 165 § 1 pkt 2 k.k.
The article discusses the issues of possibility to qualify producing or marketing the designer drugs as an offence form article 165 § 1 point 2 cc. The analysis is subjected primarily to ratio legis of this regulation, which shows that it does not have ...
Magdalena Kowalewska-Łukuć
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