Results 31 to 40 of about 16,330 (302)
Química Nova, 2016 Drug trafficking and the introduction of new drugs onto the illicit market are one of the main challenges of the forensic community. In this study, the chemical profile of a new designer drug, 2-(4-iodine-2,5-dimethoxyphenyl)-n-[(2-methoxyphenyl)methyl ...
Pâmella F. dos Santos +11 more
doaj +1 more source
High-potency ligands for DREADD imaging and activation in rodents and monkeys
Nature Communications, 2019 Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) are a powerful tool for neuroscience, but the standard DREADD ligand, CNO, has significant drawbacks.
Jordi Bonaventura +24 more
doaj +1 more source
Frontiers in Neuroscience, 2020 Synthetic cathinones are the second largest class of new psychoactive substances (NPS) on the drug market. Despite the large number of different cathinones and their abundant use, hazard characterization is mainly limited to their potential to inhibit ...
Anne Zwartsen +4 more
doaj +1 more source
Comprehensive forensic toxicological analysis of designer drugs [PDF]
, 2013 New designer drugs are constantly emerging onto the illicit drug market and it is often difficult to validate and maintaincomprehensive analytical methods for accurate detection of these compounds.
Swortwood, Madeleine Jean +1 more
core +1 more source
Roar of meow-meow (mephedrone) in India
Journal of Mental Health and Human Behaviour, 2015 Recently, a dangerous new designer drug mephedrone has fast gained popularity among the youth and teens of India. Its abuse has soared to mount to an epidemic.
Pooja Yudhishthir Palkar +1 more
doaj +1 more source
Clinical pattern of poisoning among patients declared as taking novel recreational drugs
International Journal of Occupational Medicine and Environmental Health, 2020 Objectives Intoxication with novel psychoactive drugs poses a significant challenge for medicine due to diagnostic difficulties, complex clinical patterns resulting from the polyethiology of poisoning, and the risk of fatal complications.
Anna Krakowiak +3 more
doaj +1 more source
Beyond THC: the new generation of cannabinoid designer drugs
Frontiers in Behavioral Neuroscience, 2011 Synthetic cannabinoids are functionally similar to delta9-tetrahydrocannabinol (THC), the psychoactive principle of cannabis, and bind to the same cannabinoid receptors in the brain and peripheral organs.
Liana eFattore +3 more
doaj +1 more source
Piperazine derivatives as dangerous abused compounds
Acta Pharmaceutica, 2020 Piperazine derivatives are a group of compounds with a psychostimulant effect. They are an alternative to illegal drugs. They are being searched for recreational use due to their psychoactive and hallucinogenic effects.
Welz Anna, Koba Marcin
doaj +1 more source
Rational Drug Design Rational Drug Design
, 2017 For the past three decades rationale drug design (RDD) has been developing as an innovative, rapid and successful way to discover new drug candidates. Many strategies have been followed and several targets with diverse structures and different biological roles have been investigated. Despite the variety of computational tools available, one can broadly
Khaled H. Barakat +3 more
openaire +1 more source
Monitoring risk behaviour in adolescent pupils regarding consumption of psychoactive substances
Annals of Agricultural and Environmental Medicine, 2017 Introduction Taking psychoactive substances constitutes a significant problem for Public Health, particularly in preventing drug abuse and addiction. Objectives To estimate the amount and incidence of drug consumption in middle and high school pupils ...
Paulina Wojtyła-Buciora +8 more
doaj +1 more source