Results 31 to 40 of about 4,227,388 (391)

25C-NBOMe: preliminary data on pharmacology, psychoactive effects, and toxicity of a new potent and dangerous hallucinogenic drug [PDF]

open access: yes, 2014
Introduction. The use of novel psychoactive substances (NPSs) has rapidly increased as well as their online availability. The aim of this paper is to provide a comprehensive review of the nature and the risks associated with 25C-NBOMe, which has recently
BERSANI, FRANCESCO SAVERIO   +10 more
core   +5 more sources

Conditioned stimulus effects on paired or alternative reinforcement depend on presentation duration: Implications for conceptualizations of craving

open access: yesFrontiers in Behavioral Neuroscience, 2022
Conditioned stimuli (CS) associated with alcohol ingestion are thought to play a role in relapse by producing a craving that in turn increases motivation to drink which increases ethanol-seeking and disrupts other ongoing behavior. Alternatively, such CS
Brett C. Ginsburg   +3 more
doaj   +1 more source

Bioengineered Textiles and Nonwovens – the convergence of bio-miniaturisation and electroactive conductive polymers for assistive healthcare, portable power and design-led wearable technology [PDF]

open access: yes, 2009
Today, there is an opportunity to bring together creative design activities to exploit the responsive and adaptive ‘smart’ materials that are a result of rapid development in electro, photo active polymers or OFEDs (organic thin film electronic devices),
Oliver, Raymond   +2 more
core   +3 more sources

Novel Designer Benzodiazepines: Comprehensive Review of Evolving Clinical and Adverse Effects

open access: yesNeurology International, 2022
As tranquilizers, benzodiazepines have a wide range of clinical uses. Recently, there has been a significant rise in the number of novel psychoactive substances, including designer benzodiazepines.
Amber N. Edinoff   +9 more
doaj   +1 more source

Artificial Intelligence-Driven Designer Drug Combinations: From Drug Development to Personalized Medicine

open access: yesSLAS technology, 2018
Artificial intelligence holds great promise in transforming how drugs are designed and patients are treated. In a study recently published in Science Translational Medicine, a unique artificial intelligence platform makes efficient use of small ...
M. Rashid, E. Chow
semanticscholar   +1 more source

Designer receptor technology for the treatment of epilepsy

open access: yesEBioMedicine, 2019
Epilepsy remains refractory to medical treatment in ~30% of patients despite decades of new drug development. Neurosurgery to remove or disconnect the seizure focus is often curative but frequently contraindicated by risks of irreversible impairment to ...
Andreas Lieb   +2 more
doaj   +1 more source

Detection of Drugs of Abuse by Raman Spectroscopy [PDF]

open access: yes, 2011
Raman spectroscopy can provide rapid, sensitive, non-destructive analysis of a variety of drug types (e.g. amphetamines, alkaloids, designer drugs and date rape drugs). This review concentrates on developments in the past 15 years.
Ali   +45 more
core   +1 more source

Putting forward a model for the role of the cerebellum in cocaine-induced pavlovian memory

open access: yesFrontiers in Systems Neuroscience, 2023
Substance Use Disorder (SUD) involves emotional, cognitive, and motivational dysfunction. Long-lasting molecular and structural changes in brain regions functionally and anatomically linked to the cerebellum, such as the prefrontal cortex, amygdala ...
Ignasi Melchor-Eixea   +5 more
doaj   +1 more source

2-(4-IODO-2,5-DIMETOXIFENIL)-N-[(2-METOXIFENIL)METIL]ETAMINA OU 25I-NBOME: CARACTERIZAÇÃO QUÍMICA DE UMA DESIGNER DRUG

open access: yesQuímica Nova, 2016
Drug trafficking and the introduction of new drugs onto the illicit market are one of the main challenges of the forensic community. In this study, the chemical profile of a new designer drug, 2-(4-iodine-2,5-dimethoxyphenyl)-n-[(2-methoxyphenyl)methyl ...
Pâmella F. dos Santos   +11 more
doaj   +1 more source

E-BioFlow: Different Perspectives on Scientific Workflows [PDF]

open access: yes, 2008
We introduce a new type of workflow design system called\ud e-BioFlow and illustrate it by means of a simple sequence alignment workflow. E-BioFlow, intended to model advanced scientific workflows, enables the user to model a workflow from three ...
Breit, T.   +4 more
core   +2 more sources

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