Results 31 to 40 of about 121,553 (350)

“Being with a Buddha”: A Case Report of Methoxetamine Use in a United States Veteran with PTSD

open access: yesCase Reports in Psychiatry, 2017
Methoxetamine (MXE) is a ketamine analogue with a high affinity for the N-methyl-D-aspartate (NMDA) receptor. MXE is a newly emerging designer drug of abuse and is widely available through on-line sources and is not detected by routine urine drug screens.
Joan M. Striebel   +2 more
doaj   +1 more source

Oneiroid catatonia due to the usage of spice: The case study

open access: yesEuropean Psychiatry, 2021
Introduction Designer drugs, as a term, first came about in the 1980s. Most of these “designer drugs” have synthetic cannabinoids and other psychoactive formulas difficulty to detect. Objectives A 28 year man was referred to the hospital.
O. Pityk   +4 more
doaj   +1 more source

Rational Drug Design Paradigms: The Odyssey for Designing Better Drugs

open access: yesCombinatorial Chemistry & High Throughput Screening, 2015
Due to the time and effort requirements for the development of a new drug, and the high attrition rates associated with this developmental process, there is an intense effort by academic and industrial researchers to find novel ways for more effective drug development schemes.
Kellici T   +13 more
openaire   +4 more sources

The bridge between classical and ‘synthetic’/chemical psychoses: towards a clinical, psychopathological and therapeutic perspective [PDF]

open access: yes, 2019
© 2019 Orsolini, Chiappini, Papanti, De Berardis, Corkery and Schifano. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).
Chiappini, Stephania   +5 more
core   +2 more sources

E-BioFlow: Different Perspectives on Scientific Workflows [PDF]

open access: yes, 2008
We introduce a new type of workflow design system called\ud e-BioFlow and illustrate it by means of a simple sequence alignment workflow. E-BioFlow, intended to model advanced scientific workflows, enables the user to model a workflow from three ...
Breit, T.   +4 more
core   +2 more sources

A frame signature matrix for analysing and comparing interaction design behaviour [PDF]

open access: yes, 2012
Protocol studies are an established method to investigate design behaviour. In the context of a project to investigate novice interaction design (ID) behaviour across protocols and cultures, we found that existing design behaviour analysis frameworks did
Blyth, Richard   +5 more
core   +1 more source

The pharmacology and function of receptors for short-chain fatty acids [PDF]

open access: yes, 2015
Despite some blockbuster G protein–coupled receptor (GPCR) drugs, only a small fraction (∼15%) of the more than 390 nonodorant GPCRs have been successfully targeted by the pharmaceutical industry.
Bolognini, Daniele   +3 more
core   +1 more source

Characterization of novel nitazene recreational drugs: Insights into their risk potential from in vitro µ-opioid receptor assays and in vivo behavioral studies in mice

open access: yesPharmacological Research
2-Benzylbenzimidazole derivatives or ‘nitazenes’ are increasingly present on the recreational drug market. Here, we report the synthesis and pharmacological characterization of 15 structurally diverse nitazenes that might be predicted to emerge or grow ...
Marthe M. Vandeputte   +8 more
doaj   +1 more source

Recreational Drug Use and Fluctuating Asymmetry: Testing the Handicap Principle

open access: yesEvolutionary Psychology, 2014
Zahavi's handicap principle suggests that only organisms with good genetic quality can afford to engage in costly behaviors. Recreational drug use can be harmful to one's health and therefore might be viewed as a costly signal of one's genetic quality ...
Barbara Borkowska, Boguslaw Pawlowski
doaj   +1 more source

Morality in graphical design: reviewing professional moral issues in graphical design [PDF]

open access: yesپیکره, 2014
Dealing with moral and social responsibilities in growth process of every profession is of primary considerations and is always taken into account by officials of that profession.The subject of morality is a significant issue in the field of graphical ...
KIan Ashrafi, Sodabe Salahi
doaj   +1 more source

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