Results 141 to 150 of about 1,273,827 (295)
National Drugs Advisory Board annual report, 1986
, 1986 The National Drugs Advisory Board was established by the Minister for Health in 1966 by the National Drugs Advisory Board (Establishment) Order 1966 (5.1. No. 163·of 1966) under the Health (Corporate Bodies) Act 1961.
National Drugs Advisory Board (NDAB)
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Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
, 2005 The “art toy” phenomenon (also referred to as designer toys, vinyl toys, urban vinyl, etc) first started in Asia in the 90’s. Designer toys in general are small batch production vinyl toys done in collaboration with artists and designers, with a range of
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Trade in designer drugs in the internet [PDF]
, 2016 Handel dopalaczami jest zjawiskiem, które rozwinęło się na skutek ograniczenia dostępu do „tradycyjnych” narkotyków. Terminem „dopalacze” w mowie potocznej i w mediach są nazywane nowe substancje psychoaktywne pochodzenia naturalnego lub syntetycznego ...
Czaplejewicz, Adam
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, 2005 In recent years, a number of newer designer drugs have entered the illicit drug market. The methylenedioxy-derivates of amphetamine represent the largest group of designer drugs. This paper describes a method for screening for and quantification of ten 2,
BOATTO, Gianpiero +6 more
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Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
New mind-altering drugs being detected at a rate of two per week.
, 2015 New psychoactive drugs are being detected in Europe at a rate of two per week, new data from the EU drugs agency has revealed. According to the EMCDDA, a total of 101 new mind-altering substances – known as ‘designer drugs’ were reported last year ...
Brophy, Daragh
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