Results 231 to 240 of about 1,273,827 (295)

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Oxytocin receptor neurons in the paraventricular thalamus as a nexus for social behaviour and fear. [PDF]

Brain
Yamamuro K, Ikehara M, Noriyama Y, Okuda M, Okumura K, Matsuoka K, Kashida N, Ishida R, Takeda T, Toritsuka M, Ochi T, Miyasaka T, Tai Y, Tatsumi K, Hattori T, Tanaka T, Saito Y, Iwata N, Makinodan M.   +18 more
europepmc   +1 more source

Chemical Characterization of an Emerging Designer Steroid, 6-Bromo-androst-4-en-3,17-dione, via NMR and LC-HRMS and GC-HRMS. [PDF]

Drug Test Anal
He G, Zhu S, Liu X, Wang Z, Zhang L, Lu J, Li J.   +6 more
europepmc   +1 more source

Large-Scale Forensic Surveillance of Seized E-Liquids Reveals an Emerging Etomidate-Analog-Centered Vaping Trend in Eastern Taiwan. [PDF]

Toxics
Lin HR.
europepmc   +1 more source

The hidden severity of new psychoactive substances: clinical evidence from emergency and intensive care admissions in Taiwan. [PDF]

Ann Intensive Care
Liao PH, Lin CC, Chang CM, Liu SW, Weng TI, Chen HY, Fang CC, Yu JH, Su YJ, Chen YC.   +9 more
europepmc   +1 more source

Special Issue "Role of Glia in Human Health and Disease". [PDF]

Int J Mol Sci
Lana D, Hirase H.
europepmc   +1 more source

Bioanalysis of New Designer Drugs

Bioanalysis, 2010
Since the late 1990s the illicit drug market has undergone considerable change: along with the traditional drugs of abuse that still dominate, more than 100 psychotropic substances designed to bypass controlled substances legislation have appeared and led to intoxications and fatalities.
Wohlfarth, Ariane, Weinmann, Wolfgang
openaire   +5 more sources

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New Designer Drugs

Emergency Medicine Clinics of North America, 2021
In recent years, there has been an emergence of numerous novel drugs. Such toxicity may occur in both adolescents and adults. This article discusses the opioid epidemic and several emerging opioids, including buprenorphine, loperamide, fentanyl, fentanyl derivatives, and others.
Michael, Levine, Frank, Lovecchio
openaire   +2 more sources

Designer Drugs 2.0

Clinical Pharmacology & Therapeutics, 2017
This “Designer Drugs 2.0” issue of Clinical Pharmacology & Therapeutics focuses on novel psychoactive substances, primarily cannabinoids and cathinones, and the repurposing of established psychoactive compounds (e.g., modafinil, psilocybin, lysergic acid diethylamide, and 3,4‐methylenedioxymethamphetamine) that simultaneously offer new ...
M A, Huestis, R F, Tyndale
openaire   +2 more sources

VIP and Drug Design

Current Pharmaceutical Design, 2003
The following review outlines the physiological outcome of VIP and VIP gene manipulations. Previously, we reviewed the various VIP receptors associated with biological functions ranging from growth regulation, sexual function, bronchodilation, vasodilation and immune interactions to neurotrophism. VIP-based drug design is discussed below.
Illana, Gozes, Sharon, Furman
openaire   +2 more sources