Results 251 to 260 of about 16,272 (302)
Bioanalysis of New Designer Drugs
Bioanalysis, 2010 Since the late 1990s the illicit drug market has undergone considerable change: along with the traditional drugs of abuse that still dominate, more than 100 psychotropic substances designed to bypass controlled substances legislation have appeared and led to intoxications and fatalities.
Wohlfarth, Ariane, Weinmann, Wolfgang
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Emergency Medicine Clinics of North America, 2021
In recent years, there has been an emergence of numerous novel drugs. Such toxicity may occur in both adolescents and adults. This article discusses the opioid epidemic and several emerging opioids, including buprenorphine, loperamide, fentanyl, fentanyl derivatives, and others.
Michael, Levine, Frank, Lovecchio
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In recent years, there has been an emergence of numerous novel drugs. Such toxicity may occur in both adolescents and adults. This article discusses the opioid epidemic and several emerging opioids, including buprenorphine, loperamide, fentanyl, fentanyl derivatives, and others.
Michael, Levine, Frank, Lovecchio
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Clinical Pharmacology & Therapeutics, 2017
This “Designer Drugs 2.0” issue of Clinical Pharmacology & Therapeutics focuses on novel psychoactive substances, primarily cannabinoids and cathinones, and the repurposing of established psychoactive compounds (e.g., modafinil, psilocybin, lysergic acid diethylamide, and 3,4‐methylenedioxymethamphetamine) that simultaneously offer new ...
M A, Huestis, R F, Tyndale
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This “Designer Drugs 2.0” issue of Clinical Pharmacology & Therapeutics focuses on novel psychoactive substances, primarily cannabinoids and cathinones, and the repurposing of established psychoactive compounds (e.g., modafinil, psilocybin, lysergic acid diethylamide, and 3,4‐methylenedioxymethamphetamine) that simultaneously offer new ...
M A, Huestis, R F, Tyndale
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Current Pharmaceutical Design, 2003
The following review outlines the physiological outcome of VIP and VIP gene manipulations. Previously, we reviewed the various VIP receptors associated with biological functions ranging from growth regulation, sexual function, bronchodilation, vasodilation and immune interactions to neurotrophism. VIP-based drug design is discussed below.
Illana, Gozes, Sharon, Furman
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The following review outlines the physiological outcome of VIP and VIP gene manipulations. Previously, we reviewed the various VIP receptors associated with biological functions ranging from growth regulation, sexual function, bronchodilation, vasodilation and immune interactions to neurotrophism. VIP-based drug design is discussed below.
Illana, Gozes, Sharon, Furman
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Archives of Biochemistry and Biophysics, 2017
The use of NMR as a tool to determine 3 dimensional protein solution structures, once a darling of the pharmaceutical industry, has largely given way to study of the interaction of prospective drugs with macromolecular targets. Many of these approaches involve ligand-centered studies, which have the advantage of speed and efficiency, but there are also
Mary J, Harner +3 more
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The use of NMR as a tool to determine 3 dimensional protein solution structures, once a darling of the pharmaceutical industry, has largely given way to study of the interaction of prospective drugs with macromolecular targets. Many of these approaches involve ligand-centered studies, which have the advantage of speed and efficiency, but there are also
Mary J, Harner +3 more
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Emergency Medicine Clinics of North America, 1990
Despite the increasing use of other illicit drugs, opioid abuse, overdose, and the ensuing medical complications continue to pose management challenges for the emergency physician. Heroin use is increasing as abusers of cocaine seek a drug to prolong cocaine's effects while blunting the postcocaine depression.
M, Ford, R S, Hoffman, L R, Goldfrank
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Despite the increasing use of other illicit drugs, opioid abuse, overdose, and the ensuing medical complications continue to pose management challenges for the emergency physician. Heroin use is increasing as abusers of cocaine seek a drug to prolong cocaine's effects while blunting the postcocaine depression.
M, Ford, R S, Hoffman, L R, Goldfrank
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Biochemical Pharmacology, 1975
Abstract Parachor has been used extensively in physical organic chemistry for structure determination. It has rarely been used as a parameter for the correlation of structure and biological activity. We have reexamined the parachor concept for structure-activity correlations of some closely related analogs.
P, Ahmad, C A, Fyfe, A, Mellors
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Abstract Parachor has been used extensively in physical organic chemistry for structure determination. It has rarely been used as a parameter for the correlation of structure and biological activity. We have reexamined the parachor concept for structure-activity correlations of some closely related analogs.
P, Ahmad, C A, Fyfe, A, Mellors
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