Results 41 to 50 of about 402,644 (264)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Transcendent Philosophy, Na’eeni School, and Muhammad Taghi Ja’fari on Free will and Necessity [PDF]
پژوهشنامه فلسفه دین, 2014 The relation between free will and necessity is one of the most important issues regarding the problem of “free will”. This is because of the rule which indicates that “being not necessary, an event would not be came off”.
abdollah nasri
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Violencia y cuerpo agotado en la Segunda Parte de Don Quijote de la Mancha
Criticón, 2020 The present study dwells on the various forms of physical violence in the second part of the Don Quixote de la Mancha, in connection with the theme of bodily decay.
Philippe Rabaté
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Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Belonging and Longing: The Question of the Subject in Renaud Barbaras and Jean-Luc Marion
Text MattersThe philosophy of Renaud Barbaras and Jean-Luc Marion departs from the transcendental role of the subject. No longer is the subject regarded as its own foundation, nor does it own or constitute its objects.
Szczepan Urbaniak
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The changing career of luxury: From moral threat to material well-being
Research in Hospitality Management, 2021 The elusive nature of luxury and its history have been discussed for thousands of years. Previously known to be for the rich and famous, it could be argued that luxury is a moral threat to society, bringing about social divides and tension.
Christopher J. Berry
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Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Hooked on an Affect: Detroit Techno and Dystopian Digital Culture
Dancecult: Journal of Electronic Dance Music Culture, 2011 Detroit techno is typically historicized as having grown out of the late 1970s and early 1980s middle-class, consumerist, and aspirational high school social party scene, giving the impression that Detroit techno artists created forward-thinking music as
Richard Pope
doaj
Is Agglomeration Desirable? [PDF]
Annals of Economics and Statistics, 2009 By introducing heterogeneity between high-skilled mobile and low-skill immobile workers in a model with land rent and commuting costs we develop a new model in the field of the new model in the field of the new economic geography. This model, which can reveal a dispersion-agglomeration-dispersion configuration when trade gets freer, is used to compare ...
openaire +3 more sources