Results 61 to 70 of about 403,574 (263)
The Role of Fantasy in Divorce (A Study of Seven Young Divorced Couples in Isfahan) [PDF]
جامعه شناسی کاربردی, 2015 نظریههای آسیبشناسانه به پیروی از فلسفه آگاهی برآنند که کجروی افراد؛ یعنی سوژههای انسانی را متأثر از تعیّنات اجتماعی بیرونی و انگیزههای درونی تبیین و تفسیر کنند. این نظریهها عموماً سوژه آگاه را به عنوان پیشانگاشت در تحلیل خود قرار میدهند.
Rahman Veisi +2 more
doaj
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Education in the North, 2009 Participant self observation is a form of critical autoethnography developed as a means to theorise institutional identifications and which seeks to unravel the question posed by Gilles Deleuze, ‘why do we desire what oppresses us?’ PSO is located within
Cate Watson
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
On law’s origin<br>Derrida reading Freud, Kafka and Lévi-Strauss
Utrecht Law Review, 2011 This article's main focus is 'Before the Law', a text by Derrida on Kafka's Before the Law, in which Derrida also comments on Freud's Totem and Taboo. Freud, in this text, enquires into the origins of religion, morality, social institutions and law.
Jacques de Ville
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Library Trends, 2018 "This essay examines the heterogeneous process of browsing pornography online. It begins with a discussion of the way in which our experiences of leisure and duration occur concomitantly and simultaneously. In these instances, the temporally linear experience of duration becomes disrupted by moments of immersion into a pleasurable activity.
openaire +2 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source