Results 71 to 80 of about 402,644 (264)
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
The Role of Fantasy in Divorce (A Study of Seven Young Divorced Couples in Isfahan) [PDF]
جامعه شناسی کاربردی, 2015 نظریههای آسیبشناسانه به پیروی از فلسفه آگاهی برآنند که کجروی افراد؛ یعنی سوژههای انسانی را متأثر از تعیّنات اجتماعی بیرونی و انگیزههای درونی تبیین و تفسیر کنند. این نظریهها عموماً سوژه آگاه را به عنوان پیشانگاشت در تحلیل خود قرار میدهند.
Rahman Veisi +2 more
doaj
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Education in the North, 2009 Participant self observation is a form of critical autoethnography developed as a means to theorise institutional identifications and which seeks to unravel the question posed by Gilles Deleuze, ‘why do we desire what oppresses us?’ PSO is located within
Cate Watson
doaj +1 more source
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
On law’s origin<br>Derrida reading Freud, Kafka and Lévi-Strauss
Utrecht Law Review, 2011 This article's main focus is 'Before the Law', a text by Derrida on Kafka's Before the Law, in which Derrida also comments on Freud's Totem and Taboo. Freud, in this text, enquires into the origins of religion, morality, social institutions and law.
Jacques de Ville
doaj +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
A desirable surgeon to be desired
Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association), 2010 新臨床研修制度の影響を強く受けて，外科の門をくぐる若手医師の数は減少してきており，外科医療の崩壊も一部に危惧されている．これに至った問題点を明確にして，どのような解決法があるのかを検討することを本学会総会の一つの目的としているが，こうした状況においては若手外科医の教育，人材育成がさらに重要である．そうした意味合いから本メインテーマを表記のようにしている．臨床外科医に求められていることはまさしく「高度な手術技能と知識を備えていること」であり，また同時に「豊かな人間性を備えていていること」が，その付託に応えられる必要条件となる．このような外科医をどう育成していくのかがまた，指導者たちには求められている．大阪医科大学外科学教室は一般・消化器外科学教室となった昭和51年より35年の歴史を持つが ...
openaire +2 more sources