Results 81 to 90 of about 851,141 (296)
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
On law’s origin<br>Derrida reading Freud, Kafka and Lévi-Strauss
Utrecht Law Review, 2011 This article's main focus is 'Before the Law', a text by Derrida on Kafka's Before the Law, in which Derrida also comments on Freud's Totem and Taboo. Freud, in this text, enquires into the origins of religion, morality, social institutions and law.
Jacques de Ville
doaj +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
Macroeconomic Dynamics, 2016 This paper explores the impact of gender differences in the desire for sex and the distribution of power in the household on the onset of the demographic transition and the take-off to growth. Depending on the price and efficacy of modern contraceptives, the gender wage gap, and female bargaining power, the economy assumes one of two possible ...
openaire +4 more sources
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
FEBS Open Bio, EarlyView.Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
Hamlet e o problema da verdade
Psicologia: Teoria e PesquisaEste artigo discute o problema da verdade, a partir da obra Hamlet e da produção teórica da Psicanálise. Objetiva mostrar a centralidade de tal problema, tanto no teatro quanto no processo analítico, e explorar alguns de seus aspectos tais como a ...
Maria Thereza Ávila Dantas Coelho
doaj +1 more source
W fabryce pragnienia. Gillesa Deleuze'a i Felixa Guattariego teoria nieświadomego [The Factory of Desire. Gilles Deleuze and Felix Guattari's Theory of the Unconscious] [PDF]
Analiza i Egzystencja, 2012 The text presents the theory of the unconscious that can be found in the worksof the philosophico-psychoanalytical pair of French thinkers: Gilles Deleuzeand Felix Guattari. Their theory was conceived in opposition to the classicalfreudian psychoanalysis
Krzysztof Skonieczny
doaj
A desirable surgeon to be desired
Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association), 2010 新臨床研修制度の影響を強く受けて，外科の門をくぐる若手医師の数は減少してきており，外科医療の崩壊も一部に危惧されている．これに至った問題点を明確にして，どのような解決法があるのかを検討することを本学会総会の一つの目的としているが，こうした状況においては若手外科医の教育，人材育成がさらに重要である．そうした意味合いから本メインテーマを表記のようにしている．臨床外科医に求められていることはまさしく「高度な手術技能と知識を備えていること」であり，また同時に「豊かな人間性を備えていていること」が，その付託に応えられる必要条件となる．このような外科医をどう育成していくのかがまた，指導者たちには求められている．大阪医科大学外科学教室は一般・消化器外科学教室となった昭和51年より35年の歴史を持つが ...
openaire +2 more sources
FEBS Open Bio, EarlyView.We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source