NAT10‐Mediated ac4C Modification of circANKRD12 Reprograms the Tumor Microenvironment [PDF]
Developing anticancer strategies that simultaneously target both tumor proliferation and the immunosuppressive microenvironment remains a major challenge.
Jiale Zhang +8 more
doaj +3 more sources
A prospective, observational study of efficacy and safety of desloratadine and bilastine in patients of chronic spontaneous urticaria [PDF]
Purpose: Urticaria is a disease where there is development of short-lived itchy wheals (hives), angioedema, or both.[1] With a lifetime prevalence of up to 22%, it is a widespread skin disorder that affects the general population.
Suchi Bansod +6 more
doaj +2 more sources
Desloratadine Induces TP53-Dependent Apoptosis in MCF-7 Breast Cancer Cells [PDF]
Breast cancer remains a leading cause of mortality among women despite advances in early detection and targeted therapies, underscoring the need for safer and more effective treatment options.
Syed Rashel Kabir +7 more
doaj +2 more sources
Inhibition of Cold Urticaria by Desloratadine
The effect of 5 mg desloratadine for 4 days was tested with ice-cubes before and after 4 days of treatment in 12 patients with cold urticaria. They had been asked not to take any antihistamine for at least 4 days.To find the effect of desloratadine on wheals and itching induced by cold.Ice-cubes in a thin plastic foil were placed on the inside of ...
L Juhlin
exaly +3 more sources
Efficacy of Combined Oral Isotretinoin and Desloratadine or Levocetirizine vs. Isotretinoin Monotherapy in Treating Acne Vulgaris: A Systematic Review and Meta-Analysis of Randomized Controlled Trials [PDF]
Background/Objectives: Acne vulgaris is a widespread, chronic inflammatory skin condition that significantly impacts patients’ quality of life.
Julia Woźna +5 more
doaj +2 more sources
THE CLINICAL EFFICACY OF DESLORATADINE, A NON-SEDATING ANTIHISTAMINE, IN THE MANAGEMENT OF ALLERGIC CONDITIONS: A REVIEW OF THE EVIDENCE [PDF]
Desloratadine is a relatively new, second-generation, tricyclic antihistamine which came into medical use in 2001. This study aimed to review the available evidence in the literature around the clinical efficacy of desloratadine on a range of allergic ...
Aida Forough +5 more
doaj +1 more source
Objective: The present study aimed to analyze the risk factors correlated with overactive bladder (OAB), observe the effects of desloratadine in the treatment of OAB, and explore the correlation between OAB and atopic constitution in children.Methods ...
Yue Zheng +6 more
doaj +1 more source
Desloratadine, a Novel Antigrowth Reagent for Bladder Cancer
Desloratadine, a potent antagonist for human histamine H1 receptor, has been revealed to exhibit antihistaminic activity and anti-inflammatory activity.
Jianfeng Ma MM +7 more
doaj +1 more source
Clinical Correlation Between Overactive Bladder and Allergy in Children
Background:The International Children's Continence Society defines overactive bladder (OAB) as a clinical syndrome characterized by urgency of urination usually accompanied by frequent urination and nocturia symptoms.
Lu Yin +7 more
doaj +1 more source
Histological and Biochemical Evaluation of the Effect of Desloratadine Drug in Parotid Gland Tissues [PDF]
Background: The functional deterioration of salivary glands is a consequence of a wide range of factors and significantly interfered with life quality. Desloratadine (an antihistamine) is among the drugs listed to cause dry mouth; however, its effect on ...
Intesar J. Mohammed . +3 more
doaj +1 more source

