ABSTRACT Plant vasculature is essential for the transport of water, nutrients, and signaling molecules across organs, while also providing critical mechanical support for growth and development. Disruptions in vascular bundle formation can therefore lead to severe physiological and developmental defects.
Anuradha Dhingra +2 more
wiley +1 more source
Case Report: Pulmonary benign metastasizing leiomyoma with mild <sup>18</sup>F-FDG uptake occurring 30 years after hysterectomy. [PDF]
Zou H, Chen S.
europepmc +1 more source
Proteomic Profiling of Myofiber Repair Annexins and Their Role in Duchenne Muscular Dystrophy
ABSTRACT Myofiber regeneration and membrane repair play crucial roles in maintaining the continuous physiological functioning of the neuromuscular system. A swift and efficient repair mechanism enables the rapid restoration of sarcolemmal integrity following cellular impairment in damaged skeletal muscles.
Paul Dowling +6 more
wiley +1 more source
Glioma-associated oncogene homolog 1-altered mesenchymal tumour of the upper oesophageal sphincter. [PDF]
Hebert S +3 more
europepmc +1 more source
Novel truncating Desmin mutation Arg150Stop disrupts structural integrity and cellular homeostasis by formation of persistent aggregate-like structure. [PDF]
Mitra S +6 more
europepmc +1 more source
Sustained Activation of CaMKII Promotes Skeletal Muscle Contractile Dysfunction in Aging
CaMKII exemplifies antagonistic pleiotropy in skeletal muscle. Exercise‐related Ca2+/redox signals drive transient CaMKII activation supporting youthful performance. Here we show CaMKII is upregulated in aged muscle, where dysregulated Ca2+/redox signals likely sustain its activity; constitutively active CaMKII recapitulates aging‐associated ...
Michael R. Bene +15 more
wiley +1 more source
Management of a large angiomyofibroblastoma of the vulva: a case report describing radical excision and reconstruction. [PDF]
Sierant A +3 more
europepmc +1 more source
Background and Purpose Metabolic dysfunction‐associated steatohepatitis (MASH) is linked to activation of hepatic stellate cells (HSCs) to α‐smooth muscle actin–positive myofibroblasts that produce collagen and proinflammatory cytokines. Quiescent HSCs express the NO‐cGMP signalling axis.
Krithika Rajeeth +14 more
wiley +1 more source
Stimulating proteasomal degradation in human proteinopathies
The proteasome mediates the degradation of a wide range of proteins. Boosting proteasomal degradation may be beneficial in several disease contexts and can be achieved either by modulating proteasome activity or by improving substrate delivery. Proteasome activity can be enhanced by increasing proteasome abundance, inducing constitutive gate opening ...
Maria E. Gierisch +2 more
wiley +1 more source
Endometrial Polyp and Vaginal Superficial Myofibroblastoma following Tamoxifen Use: A Case Study. [PDF]
Kim MS, Lee HH, Han E, Park YJ, Kim TH.
europepmc +1 more source

