Results 1 to 10 of about 25,961 (162)

FGF6 in myogenesis

Biochimica Et Biophysica Acta - Molecular Cell Research, 2006
Important functions in myogenesis have been proposed for FGF6, a member of the fibroblast growth factor family accumulating almost exclusively in the myogenic lineage. However, the analyses of Fgf6 (-/-) mutant mice gave contradictory results and the role of FGF6 during myogenesis remained largely unclear.
Christophe Chanoine
exaly   +5 more sources

Coupling between Myogenesis and Angiogenesis during Skeletal Muscle Regeneration Is Stimulated by Restorative Macrophages

Stem Cell Reports, 2017
Summary: In skeletal muscle, new functions for vessels have recently emerged beyond oxygen and nutrient supply, through the interactions that vascular cells establish with muscle stem cells. Here, we demonstrate in human and mouse that endothelial cells (
Claire Latroche, Michele Weiss-Gayet, Laurent Müller   +2 more
exaly   +3 more sources

Wnt signaling in myogenesis [PDF]

Trends in Cell Biology, 2012
The formation of skeletal muscle is a tightly regulated process that is critically modulated by Wnt signaling. Myogenesis is dependent on the precise and dynamic integration of multiple Wnt signals allowing self-renewal and progression of muscle precursors in the myogenic lineage.
Julia Von Maltzahn, Natasha C Chang, C Florian Bentzinger   +2 more
exaly   +3 more sources

Non-regenerative myogenesis in adult skeletal muscles: myofiber death-independent muscle satellite cell expansion [PDF]

Skeletal Muscle
Muscle regeneration processes triggered by injuries following myofiber death have been extensively investigated owing to the availability of suitable in vivo animal models, including disease models.
So-ichiro Fukada, Atsushi Kubo, Takashi Yamada, Takayuki Akimoto   +3 more
doaj   +2 more sources

The Role of Oxidative Stress in Skeletal Muscle Myogenesis and Muscle Disease

Antioxidants, 2022
The contractile activity, high oxygen consumption and metabolic rate of skeletal muscle cause it to continuously produce moderate levels of oxidant species, such as reactive oxygen species (ROS) and reactive nitrogen species (RNS).
Di Lian, Mingming Chen, Hanyu Wu
exaly   +3 more sources

Pitx2 Differentially Regulates the Distinct Phases of Myogenic Program and Delineates Satellite Cell Lineages During Muscle Development

Frontiers in Cell and Developmental Biology, 2022
The knowledge of the molecular mechanisms that regulate embryonic myogenesis from early myogenic progenitors to myoblasts, as well as the emergence of adult satellite stem cells (SCs) during development, are key concepts to understanding the genesis and ...
Felícitas Ramírez de Acuña, Felícitas Ramírez de Acuña, Francisco Hernandez-Torres, Francisco Hernandez-Torres, Francisco Hernandez-Torres, Lara Rodriguez-Outeiriño, Lara Rodriguez-Outeiriño, Jorge N. Dominguez, Jorge N. Dominguez, Lidia Matias-Valiente, Lidia Matias-Valiente, Cristina Sanchez-Fernandez, Cristina Sanchez-Fernandez, Diego Franco, Diego Franco, Amelia E. Aranega, Amelia E. Aranega   +16 more
doaj   +1 more source

miR-106b is a novel target to promote muscle regeneration and restore satellite stem cell function in injured Duchenne dystrophic muscle

Molecular Therapy: Nucleic Acids, 2022
Satellite cells (SCs), muscle stem cells, display functional heterogeneity, and dramatic changes linked to their regenerative capabilities are associated with muscle-wasting diseases.
Lara Rodriguez-Outeiriño, Francisco Hernandez-Torres, Felicitas Ramirez de Acuña, Alberto Rastrojo, Carlota Creus, Alejandra Carvajal, Luis Salmeron, Marisol Montolio, Patricia Soblechero-Martin, Virginia Arechavala-Gomeza, Diego Franco, Amelia Eva Aranega   +11 more
doaj   +1 more source

Mitochondrial Oxidative Stress and Mitophagy Activation Contribute to TNF-Dependent Impairment of Myogenesis

Antioxidants, 2023
Many muscular pathologies are associated with oxidative stress and elevated levels of the tumor necrosis factor (TNF) that cause muscle protein catabolism and impair myogenesis.
Daniil A. Chernyavskij, Olga Yu. Pletjushkina, Anastasia V. Kashtanova, Ivan I. Galkin, Anna Karpukhina, Boris V. Chernyak, Yegor S. Vassetzky, Ekaterina N. Popova   +7 more
doaj   +1 more source

TNF Signaling Acts Downstream of MiR-322/-503 in Regulating DM1 Myogenesis

Frontiers in Endocrinology, 2022
Myotonic dystrophy type 1 (DM1) is caused by the expanded CUG repeats and usually displays defective myogenesis. Although we previously reported that ectopic miR-322/-503 expression improved myogenesis in DM1 by targeting the toxic RNA, the underlying ...
Meng Li, Meng Li, Meng Li, Feng Xu, Zhongxian Liu, Zhongxian Liu, Zhongxian Liu, Chunguang Wang, Chunguang Wang, Chunguang Wang, Yun Zhao, Yun Zhao, Yun Zhao, Guoping Zhu, Guoping Zhu, Guoping Zhu, Xiaopeng Shen, Xiaopeng Shen, Xiaopeng Shen   +18 more
doaj   +1 more source

Inhibition of Postn Rescues Myogenesis Defects in Myotonic Dystrophy Type 1 Myoblast Model

Frontiers in Cell and Developmental Biology, 2021
Myotonic dystrophy type 1 (DM1) is an inherited neuromuscular disease caused by expanded CTG repeats in the 3′ untranslated region (3′UTR) of the DMPK gene.
Xiaopeng Shen, Xiaopeng Shen, Xiaopeng Shen, Zhongxian Liu, Zhongxian Liu, Zhongxian Liu, Chunguang Wang, Chunguang Wang, Chunguang Wang, Feng Xu, Feng Xu, Feng Xu, Jingyi Zhang, Jingyi Zhang, Jingyi Zhang, Meng Li, Meng Li, Meng Li, Yang Lei, Ao Wang, Ao Wang, Ao Wang, Chao Bi, Chao Bi, Chao Bi, Guoping Zhu, Guoping Zhu, Guoping Zhu   +27 more
doaj   +1 more source