Results 1 to 10 of about 19,233,520 (354)
microRNAs in skeletal muscle development [PDF]
Seminars in Cell & Developmental Biology, 2017 A fundamental process during both embryo development and stem cell differentiation is the control of cell lineage determination. In developing skeletal muscle, many of the diffusible signaling molecules, transcription factors and more recently non-coding RNAs that contribute to this process have been identified.
Mok, Gi Fay +2 more
openaire +5 more sources
The International Journal of Developmental Biology, 2018 Striated muscle is the most abundant tissue in the body of vertebrates and it forms, together with the skeleton, the locomotory system required both for movement and the creation of the specific body shape of a species. Research on the embryonic development of muscles has a long tradition both in classical embryology and in molecular developmental ...
Martin, Scaal, Christophe, Marcelle
openaire +4 more sources
Muscle-specific microRNAs in skeletal muscle development
Developmental Biology, 2016 Proper muscle function constitutes a precondition for good heath and an active lifestyle during an individual's lifespan and any deviations from normal skeletal muscle development and its functions may lead to numerous health conditions including e.g. myopathies and increased mortality.
Horak, Martin +2 more
openaire +3 more sources
Mechanical forces during muscle development
Mechanisms of Development, 2017 Muscles are the major force producing tissue in the human body. While certain muscle types specialize in producing maximum forces, others are very enduring. An extreme example is the heart, which continuously beats for the entire life. Despite being specialized, all body muscles share similar contractile mini-machines called sarcomeres that are ...
Sandra B. Lemke, Frank Schnorrer
openaire +5 more sources
Epigenetic regulation of muscle development [PDF]
Journal of Muscle Research and Cell Motility, 2017 In eukaryote cells, chromatin appears in several forms and is composed of genomic DNA, protein and RNA. The protein content of chromatin is composed primarily of core histones that are packaged into nucleosomes resulting in the condensation of the DNA.
Barreiro Portela, Esther +1 more
openaire +4 more sources
Extracellular matrix: an important regulator of cell functions and skeletal muscle development
Cell & Bioscience, 2021 Extracellular matrix (ECM) is a kind of connective tissue in the cell microenvironment, which is of great significance to tissue development. ECM in muscle fiber niche consists of three layers: the epimysium, the perimysium, and the endomysium (basal ...
Weiya Zhang, Yuan-yuan Liu, Hong Zhang
semanticscholar +1 more source
Key Genes Regulating Skeletal Muscle Development and Growth in Farm Animals
Animals, 2021 Simple Summary Skeletal muscle mass is an important economic trait, and muscle development and growth is a crucial factor to supply enough meat for human consumption. Thus, understanding (candidate) genes regulating skeletal muscle development is crucial
M. Mohammadabadi +4 more
semanticscholar +1 more source
A comprehensive epigenome atlas reveals DNA methylation regulating skeletal muscle development
Nucleic Acids Research, 2021 DNA methylation is important for the epigenetic regulation of gene expression and plays a critical role in mammalian development. However, the dynamic regulation of genome-wide DNA methylation in skeletal muscle development remains largely unknown. Here,
Yalan Yang +7 more
semanticscholar +1 more source
CircRNA—Protein Interactions in Muscle Development and Diseases
International Journal of Molecular Sciences, 2021 Circular RNA (circRNA) is a kind of novel endogenous noncoding RNA formed through back-splicing of mRNA precursor. The biogenesis, degradation, nucleus–cytoplasm transport, location, and even translation of circRNA are controlled by RNA-binding proteins (
Shuailong Zheng +15 more
semanticscholar +1 more source
Engineered skeletal muscle recapitulates human muscle development, regeneration and dystrophy
Journal of Cachexia, Sarcopenia and Muscle, 2022 Human pluripotent stem cell‐derived muscle models show great potential for translational research. Here, we describe developmentally inspired methods for the derivation of skeletal muscle cells and their utility in skeletal muscle tissue engineering with
M. Shahriyari +21 more
semanticscholar +1 more source