Genome-Wide Footprints of Pig Domestication and Selection Revealed through Massive Parallel Sequencing of Pooled DNA [PDF]
, 2011 Background Artificial selection has caused rapid evolution in domesticated species. The identification of selection footprints across domesticated genomes can contribute to uncover the genetic basis of phenotypic diversity.
Amaral, A.J. +8 more
core +2 more sources
Molecular Therapy: Nucleic Acids, 2020 Skeletal muscle is an important metabolic organ of the body, and impaired skeletal muscle differentiation can result in a wide range of metabolic diseases.
Yihao Liu +8 more
doaj +1 more source
Acute and chronic cold exposure differentially affects the browning of porcine white adipose tissue
Animal, 2018 Piglets are characteristically cold intolerant and thus susceptible to high mortality. However, browning of white adipose tissue (WAT) can induce non-shivering thermogenesis as a potential strategy to facilitate the animal’s response to cold.
Y. Gao +7 more
doaj +1 more source
Estrogen-related receptor α (ERRα) : a novel target in type 2 diabetes [PDF]
, 2005 Recent studies have shown that reduced mitochondrial content and function in skeletal muscle are common features of type 2 diabetes. Here, we review the molecular mechanisms involved in the regulation of mitochondrial genes in skeletal muscle, focusing ...
Handschin, C., Mootha, V. K.
core +1 more source
The myogenic regulatory factors, determinants of muscle development, cell identity and regeneration.
Seminars in Cell and Developmental Biology, 2017 The Myogenic Regulatory Factors (MRFs) Myf5, MyoD, myogenin and MRF4 are members of the basic helix-loop-helix family of transcription factors that control the determination and differentiation of skeletal muscle cells during embryogenesis and postnatal ...
J. Hernández-Hernández +3 more
semanticscholar +1 more source
Cholesterol-derived glucocorticoids control early fate specification in embryonic stem cells
Stem Cell Research, 2015 Aside from its role in cell membrane integrity, cholesterol is a key component in steroid hormone production. The vital functions of steroid hormones such as estrogen, testosterone, glucocorticoids (Gcrts) and mineralocorticoids (Mnrts) in perinatal and ...
Joaquim Cabral-Teixeira +5 more
doaj +1 more source
The association between muscle strength and activity limitations in patients with the hypermobility type of Ehlers–Danlos syndrome : the impact of proprioception [PDF]
, 2016 Purpose: The patients diagnosed with Ehlers-Danlos Syndrome Hypermobility Type (EDS-HT) are characterized by pain, proprioceptive inacuity, muscle weakness, potentially leading to activity limitations.
Calders, Patrick +8 more
core +2 more sources
Lengthened partial repetitions elicit similar muscular adaptations as full range of motion repetitions during resistance training in trained individuals [PDF]
PeerJPurpose Resistance training using different ranges of motion may produce varying effects on musclular adaptations. The purpose of this study was to compare the effects of lengthened partial repetitions (LPs) vs.
Milo Wolf +12 more
doaj +2 more sources
What determines growth potential and juvenile quality of farmed fish species? [PDF]
, 2013 Enhanced production of high quality and healthy fry is a key target for a successful and competitive expansion of the aquaculture industry. Although large quantities of fish larvae are produced, survival rates are often low or highly variable and growth ...
Alami-Durante +225 more
core +3 more sources
Bone size and bone strength are increased in obese male adolescents [PDF]
, 2013 Context: Controversy exists on the effect of obesity on bone development during puberty. Objective: Our objective was to determine differences in volumetric bone mineral density (vBMD) and bone geometry in male obese adolescents (ObAs) in overlap with ...
De Schepper, Jean +11 more
core +2 more sources