Results 21 to 30 of about 54,460 (292)

Drosophila myogenesis [PDF]

Current Biology, 2016
The skeletal muscle system is the largest organ in motile animals, constituting between 35 and 55% of the human body mass, and up to 75% of the body mass in flying organisms like Drosophila. The flight muscles alone in flying insects comprise up to 65% of total body mass.
Ingo, Bothe, Mary K, Baylies
openaire   +2 more sources

TNF Signaling Acts Downstream of MiR-322/-503 in Regulating DM1 Myogenesis

Frontiers in Endocrinology, 2022
Myotonic dystrophy type 1 (DM1) is caused by the expanded CUG repeats and usually displays defective myogenesis. Although we previously reported that ectopic miR-322/-503 expression improved myogenesis in DM1 by targeting the toxic RNA, the underlying ...
Meng Li, Meng Li, Meng Li, Feng Xu, Zhongxian Liu, Zhongxian Liu, Zhongxian Liu, Chunguang Wang, Chunguang Wang, Chunguang Wang, Yun Zhao, Yun Zhao, Yun Zhao, Guoping Zhu, Guoping Zhu, Guoping Zhu, Xiaopeng Shen, Xiaopeng Shen, Xiaopeng Shen   +18 more
doaj   +1 more source

Inhibition of Postn Rescues Myogenesis Defects in Myotonic Dystrophy Type 1 Myoblast Model

Frontiers in Cell and Developmental Biology, 2021
Myotonic dystrophy type 1 (DM1) is an inherited neuromuscular disease caused by expanded CTG repeats in the 3′ untranslated region (3′UTR) of the DMPK gene.
Xiaopeng Shen, Xiaopeng Shen, Xiaopeng Shen, Zhongxian Liu, Zhongxian Liu, Zhongxian Liu, Chunguang Wang, Chunguang Wang, Chunguang Wang, Feng Xu, Feng Xu, Feng Xu, Jingyi Zhang, Jingyi Zhang, Jingyi Zhang, Meng Li, Meng Li, Meng Li, Yang Lei, Ao Wang, Ao Wang, Ao Wang, Chao Bi, Chao Bi, Chao Bi, Guoping Zhu, Guoping Zhu, Guoping Zhu   +27 more
doaj   +1 more source

Time-resolved phosphoproteome and proteome analysis reveals kinase signaling on master transcription factors during myogenesis

iScience, 2022
Summary: Myogenesis is governed by signaling networks that are tightly regulated in a time-dependent manner. Although different protein kinases have been identified, knowledge of the global signaling networks and their downstream substrates during ...
Di Xiao, Marissa Caldow, Hani Jieun Kim, Ronnie Blazev, Rene Koopman, Deborah Manandi, Benjamin L. Parker, Pengyi Yang   +7 more
doaj   +1 more source

In-vitro human myogenesis model reveals novel mRNA alternative splicing isoforms. [PDF]

Sci Rep
Donega S, Banskota N, Yang JH, Rossi M, Piao Y, Tsitsipatis D, Fan J, De S, Peterson CA, McDermott MM, Gorospe M, Ferrucci L.   +11 more
europepmc   +3 more sources

Sprouty2 mediated tuning of signalling is essential for somite myogenesis [PDF]

, 2015
Background: Negative regulators of signal transduction cascades play critical roles in controlling different aspects of normal embryonic development.
A Borycki, A Faedo, A Sasaki, AA Mailleux, AC Rios, Andrea Münsterberg, B Christ, B Hausott, C de Alvaro, C Marcelle, C Zhang, CC Lee, D Chambers, D Sayed, D Sweetman, D Sweetman, G Christofori, G Minowada, GF Mok, Grant Wheeler, H Hanafusa, HJ Kim, HM Poppleton, I Laziz, JD Tefft, JM Mason, JM Mason, K Matsumura, K Shim, Katarzyna Goljanek Whysall, L Cheng, L Chi, L Chi, LE Alvares, M Abu-Elmagd, M Buckingham, M Ishida, M Schmidt, M Schmidt, MA Basson, MA Cabrita, MC Eblaghie, MJ Frank, Muhammad Abu-Elmagd, N Hacohen, OD Klein, P Li, PA Branney, S Eloy-Trinquet, TG Smith, V Hamburger, Y Yigzaw   +51 more
core   +8 more sources

Disease-associated metabolic alterations that impact satellite cells and muscle regeneration: perspectives and therapeutic outlook

Nutrition & Metabolism, 2021
Many chronic disease patients experience a concurrent loss of lean muscle mass. Skeletal muscle is a dynamic tissue maintained by continuous protein turnover and progenitor cell activity. Muscle stem cells, or satellite cells, differentiate (by a process
Josiane Joseph, Jason D. Doles
doaj   +1 more source

Comparative analyses by sequencing of transcriptomes during skeletal muscle development between pig breeds differing in muscle growth rate and fatness. [PDF]

PLoS ONE, 2011
Understanding the dynamics of muscle transcriptome during development and between breeds differing in muscle growth is necessary to uncover the complex mechanism underlying muscle development.
Xiao Zhao, Delin Mo, Anning Li, Wen Gong, Shuqi Xiao, Yue Zhang, Limei Qin, Yuna Niu, Yunxue Guo, Xiaohong Liu, Peiqing Cong, Zuyong He, Chong Wang, Jiaqi Li, Yaosheng Chen   +14 more
doaj   +1 more source

Pitx2 in Embryonic and Adult Myogenesis

Frontiers in Cell and Developmental Biology, 2017
Skeletal muscle is a heterogeneous tissue that represents between 30 and 38% of the human body mass and has important functions in the organism, such as maintaining posture, locomotor impulse, or pulmonary ventilation.
Amelia E. Aranega, Amelia E. Aranega, Francisco Hernandez-Torres, Francisco Hernandez-Torres, Lara Rodríguez-Outeiriño, Lara Rodríguez-Outeiriño, Diego Franco, Diego Franco   +7 more
doaj   +1 more source

Smad7:β-catenin Complex Regulates Myogenic Gene Transcription [PDF]

, 2019
Recent reports indicate that Smad7 promotes skeletal muscle differentiation and growth. We previously documented a non-canonical role of nuclear Smad7 during myogenesis, independent of its role in TGF-β signaling.
McDermott, John, Tetsuake, Miyake, Tripathi, Soma   +2 more
core   +1 more source