Results 1 to 10 of about 34,104 (165)

IL-4 Signaling Promotes Myoblast Differentiation and Fusion by Enhancing the Expression of MyoD, Myogenin, and Myomerger

open access: yesCells, 2023
Myoblast fusion is essential for skeletal muscle development, growth, and regeneration. However, the molecular mechanisms underlying myoblast fusion and differentiation are not fully understood.
Mitsutoshi Kurosaka   +2 more
exaly   +3 more sources

LKB1 destabilizes microtubules in myoblasts and contributes to myoblast differentiation.

open access: yesPLoS ONE, 2012
BackgroundSkeletal muscle myoblast differentiation and fusion into multinucleate myotubes is associated with dramatic cytoskeletal changes. We find that microtubules in differentiated myotubes are highly stabilized, but premature microtubule ...
Isma Mian   +5 more
doaj   +3 more sources

MicroRNA-27b-3p Targets the Myostatin Gene to Regulate Myoblast Proliferation and Is Involved in Myoblast Differentiation

open access: yesCells, 2021
microRNAs play an important role in the growth and development of chicken embryos, including the regulation of skeletal muscle genesis, myoblast proliferation, differentiation, and apoptosis.
Genxi Zhang, Mingliang He, Pengfei Wu
exaly   +3 more sources

Effect of p38 inhibitor on the proliferation of chicken muscle stem cells and differentiation into muscle and fat [PDF]

open access: yesAnimal Bioscience, 2023
Objective Inhibiting the p38 mitogen-activated protein kinase (MAPK) signaling pathway delays differentiation and increases proliferation of muscle stem cells in most species.
Minkyung Ryu   +4 more
doaj   +1 more source

Myocyte enhancer factor 2A promotes proliferation and its inhibition attenuates myogenic differentiation via myozenin 2 in bovine skeletal muscle myoblast. [PDF]

open access: yesPLoS ONE, 2018
Myocyte enhancer factor 2A (MEF2A) is widely distributed in various tissues or organs and plays crucial roles in multiple biological processes. To examine the potential effects of MEF2A on skeletal muscle myoblast, the functional role of MFE2A in ...
Ya-Ning Wang   +5 more
doaj   +1 more source

Local GHR roles in regulation of mitochondrial function through mitochondrial biogenesis during myoblast differentiation

open access: yesCell Communication and Signaling, 2023
Background Myoblast differentiation requires metabolic reprogramming driven by increased mitochondrial biogenesis and oxidative phosphorylation. The canonical GH-GHR-IGFs axis in liver exhibits a great complexity in response to somatic growth.
Bowen Hu   +9 more
doaj   +1 more source

miR-152 Regulates Bovine Myoblast Proliferation by Targeting KLF6

open access: yesAnimals, 2021
Though miRNAs have been reported to regulate bovine myoblast proliferation, but many miRNAs still need to be further explored. Specifically, miR-152 is a highly expressed miRNA in cattle skeletal muscle tissues, but its function in skeletal muscle ...
Chengchuang Song   +11 more
doaj   +1 more source

Epidermal growth factor receptor down-regulation triggers human myoblast differentiation. [PDF]

open access: yesPLoS ONE, 2013
Initiation of human myoblast differentiation requires a negative shift (hyperpolarization) of the resting potential of myoblasts that depends on the activation of Kir2.1 potassium channels.
Marina C Leroy   +4 more
doaj   +1 more source

The Role of Embryonic Chick Muscle Cell Culture in the Study of Skeletal Myogenesis

open access: yesFrontiers in Physiology, 2021
The mechanisms involved in the development of skeletal muscle fibers have been studied in the last 70 years and yet many aspects of this process are still not completely understood.
Manoel L. Costa   +3 more
doaj   +1 more source

Evaluation of Cells and Medium Optimization for Invitro Model of Diabetic and Electrolyte Imbalance [PDF]

open access: yesBIO Web of Conferences, 2021
Metabolism syndrome has many negative impacts on human health. Various efforts and methods are attempted in the treatment of this disease. One of the methods used is CRISPR/Cas9 gene therapy.
Sebastian Alfino   +5 more
doaj   +1 more source

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