Results 21 to 30 of about 41,135 (289)

Understanding the Effects of Trenbolone Acetate, Polyamine Precursors, and Polyamines on Proliferation, Protein Synthesis Rates, and the Abundance of Genes Involved in Myoblast Growth, Polyamine Biosynthesis, and Protein Synthesis in Murine Myoblasts

Biology, 2023
Research suggests that androgens increase skeletal muscle growth by modulating polyamine biosynthesis. As such, the objective of this study was to investigate effects of anabolic hormones, polyamine precursors, and polyamines relative to proliferation ...
Laura A. Motsinger, Lillian L. Okamoto, Nikole E. Ineck, Brynne A. Udy, Christopher L. Erickson, Youssef Harraq, Caleb C. Reichhardt, Gordon K. Murdoch, Kara Jean Thornton   +8 more
doaj   +1 more source

RNAseq analysis of fast skeletal muscle in restriction-fed transgenic coho salmon (Oncorhynchus kisutch) : an experimental model uncoupling the growth hormone and nutritional signals regulating growth [PDF]

, 2015
Background Coho salmon (Oncorhynchus kisutch) transgenic for growth hormone (Gh) express Gh in multiple tissues which results in increased appetite and continuous high growth with satiation feeding. Restricting Gh-transgenics to the same lower ration (TR)
Devlin, Robert, Robert H Devlin, Johnston, Ian Alistair, Daniel Garcia de la serrana, Ian A Johnston, Garcia de la Serrana Castillo, Daniel   +5 more
core   +1 more source

Sheep recombinant IGF-1 promotes organ-specific growth in fetal sheep

Frontiers in Physiology, 2022
IGF-1 is a critical fetal growth-promoting hormone. Experimental infusion of an IGF-1 analog, human recombinant LR3 IGF-1, into late gestation fetal sheep increased fetal organ growth and skeletal muscle myoblast proliferation.
J Stremming, A White, A Donthi, DG Batt, B Hetrick, EI Chang, SR Wesolowski, MB Seefeldt, CE McCurdy, PJ Rozance, LD Brown   +10 more
doaj   +1 more source

A novel whole-cell lysate kinase assay identifies substrates of the p38 MAPK in differentiating myoblasts

Skeletal Muscle, 2012
Background The p38α mitogen-activated protein kinase (MAPK) is a critical mediator of myoblast differentiation, and does so in part through the phosphorylation and regulation of several transcription factors and chromatin remodelling proteins.
Knight James DR, Tian Ruijun, Lee Robin EC, Wang Fangjun, Beauvais Ariane, Zou Hanfa, Megeney Lynn A, Gingras Anne-Claude, Pawson Tony, Figeys Daniel, Kothary Rashmi   +10 more
doaj   +1 more source

Correction of the FSHD myoblast differentiation defect by fusion with healthy myoblasts [PDF]

Journal of Cellular Physiology, 2015
Facioscapulohumeral dystrophy (FSHD) is a neuromuscular disease with a prevalence that could reach 1 in 8,000 characterized by progressive asymmetric muscle weakness. Myoblasts isolated from FSHD muscles exhibit morphological differentiation defects and show a distinct transcription profile.
Dib, Carla, Bou Saada, Yara, Dmitriev, Petr, Richon, Catherine, Dessen, Philippe, Laoudj-Chenivesse, Dalila, Carnac, Gilles, Lipinski, Marc, Vassetzky, Yegor   +8 more
openaire   +3 more sources

circFGFR4 Promotes Differentiation of Myoblasts via Binding miR-107 to Relieve Its Inhibition of Wnt3a

Molecular Therapy: Nucleic Acids, 2018
Muscle development is regulated under a series of complicate processes, and non-coding RNAs, such as microRNAs (miRNAs) and circular RNAs (circRNAs), have been reported to play important roles in regulating myoblast proliferation and differentiation.
Hui Li, Xuefeng Wei, Jiameng Yang, Dong Dong, Dan Hao, Yongzhen Huang, Xianyong Lan, Martin Plath, Chuzhao Lei, Yun Ma, Fengpeng Lin, Yueyu Bai, Hong Chen   +12 more
doaj   +1 more source

FHL1 reduces dystrophy in transgenic mice overexpressing FSHD muscular dystrophy region gene 1 (FRG1).

PLoS ONE, 2015
Facioscapulohumeral muscular dystrophy (FSHD) is an autosomal-dominant disease with no effective treatment. The genetic cause of FSHD is complex and the primary pathogenic insult underlying the muscle disease is unknown.
Sandra J Feeney, Meagan J McGrath, Absorn Sriratana, Stefan M Gehrig, Gordon S Lynch, Colleen E D'Arcy, John T Price, Catriona A McLean, Rossella Tupler, Christina A Mitchell   +9 more
doaj   +1 more source

MEF2C Expression Is Regulated by the Post-transcriptional Activation of the METTL3-m6A-YTHDF1 Axis in Myoblast Differentiation

Frontiers in Veterinary Science, 2022
N6-methyladenosine (m6A) plays an essential role in regulating gene expression. However, the effect of m6A on skeletal myoblast differentiation and the underlying mechanisms are still unclear.
Xinran Yang, Yue Ning, Yue Ning, Sayed Haidar Abbas Raza, Chugang Mei, Chugang Mei, Linsen Zan, Linsen Zan   +7 more
doaj   +1 more source

MicroRNAs in Sarcopenia: A Systematic Review

Frontiers in Medicine, 2020
Sarcopenia, which is characterized by the loss of skeletal muscle, has been reported to contribute to development of physical disabilities, various illnesses, and increasing mortality. MicroRNAs (miRNAs) are small non-coding RNAs that inhibit translation
Katsunori Yanai, Shohei Kaneko, Hiroki Ishii, Akinori Aomatsu, Akinori Aomatsu, Kiyonori Ito, Keiji Hirai, Susumu Ookawara, Kenichi Ishibashi, Yoshiyuki Morishita   +9 more
doaj   +1 more source

Influence of Leucine on Protein Metabolism of Chicken Embryo Myoblasts is Modulated by Varying Serum Concentrations in the Medium

The Journal of Poultry Science, 2007
The influence of varying leucine and fetal calf serum (FCS) concentrations in the culture medium on protein synthesis and degradation of chicken embryo myoblasts was examined.
Mai Oki, Hiroyuki Sato, Kazuki Nakagawa, Kazumi Kita   +3 more
doaj   +1 more source