Results 21 to 30 of about 1,794 (168)

FHL1 reduces dystrophy in transgenic mice overexpressing FSHD muscular dystrophy region gene 1 (FRG1).

PLoS ONE, 2015
Facioscapulohumeral muscular dystrophy (FSHD) is an autosomal-dominant disease with no effective treatment. The genetic cause of FSHD is complex and the primary pathogenic insult underlying the muscle disease is unknown.
Sandra J Feeney, Meagan J McGrath, Absorn Sriratana, Stefan M Gehrig, Gordon S Lynch, Colleen E D'Arcy, John T Price, Catriona A McLean, Rossella Tupler, Christina A Mitchell   +9 more
doaj   +1 more source

circFGFR4 Promotes Differentiation of Myoblasts via Binding miR-107 to Relieve Its Inhibition of Wnt3a

Molecular Therapy: Nucleic Acids, 2018
Muscle development is regulated under a series of complicate processes, and non-coding RNAs, such as microRNAs (miRNAs) and circular RNAs (circRNAs), have been reported to play important roles in regulating myoblast proliferation and differentiation.
Hui Li, Xuefeng Wei, Jiameng Yang, Dong Dong, Dan Hao, Yongzhen Huang, Xianyong Lan, Martin Plath, Chuzhao Lei, Yun Ma, Fengpeng Lin, Yueyu Bai, Hong Chen   +12 more
doaj   +1 more source

MEF2C Expression Is Regulated by the Post-transcriptional Activation of the METTL3-m6A-YTHDF1 Axis in Myoblast Differentiation

Frontiers in Veterinary Science, 2022
N6-methyladenosine (m6A) plays an essential role in regulating gene expression. However, the effect of m6A on skeletal myoblast differentiation and the underlying mechanisms are still unclear.
Xinran Yang, Yue Ning, Yue Ning, Sayed Haidar Abbas Raza, Chugang Mei, Chugang Mei, Linsen Zan, Linsen Zan   +7 more
doaj   +1 more source

MicroRNAs in Sarcopenia: A Systematic Review

Frontiers in Medicine, 2020
Sarcopenia, which is characterized by the loss of skeletal muscle, has been reported to contribute to development of physical disabilities, various illnesses, and increasing mortality. MicroRNAs (miRNAs) are small non-coding RNAs that inhibit translation
Katsunori Yanai, Shohei Kaneko, Hiroki Ishii, Akinori Aomatsu, Akinori Aomatsu, Kiyonori Ito, Keiji Hirai, Susumu Ookawara, Kenichi Ishibashi, Yoshiyuki Morishita   +9 more
doaj   +1 more source

Derivation and Characterization of Novel Cytocompatible Decellularized Tissue Scaffold for Myoblast Growth and Differentiation

Cells, 2023
The selection of an appropriate scaffold is imperative for the successful development of alternative animal protein in the form of cultured meat or lab-grown meat.
Anshuman Singh, Suraj Kumar Singh, Vinod Kumar, Jalaj Gupta, Manoj Kumar, Devojit Kumar Sarma, Samradhi Singh, Manoj Kumawat, Vinod Verma   +8 more
doaj   +1 more source

Identification of transition factors in myotube formation from proteome and transcriptome analyses

Journal of Integrative Agriculture, 2023
Muscle fibers are the main component of skeletal muscle and undergo maturation through the formation of myotubes. During early development, a population of skeletal muscle satellite cells (SSCs) proliferate into myoblasts.
Qi ZHENG, Rong-cui HU, Cui-yun ZHU, Jing JING, Meng-yu LOU, Si-huan ZHANG, Shuang LI, Hong-guo CAO, Xiao-rong ZHANG, Ying-hui LING   +9 more
doaj   +1 more source

Influence of Leucine on Protein Metabolism of Chicken Embryo Myoblasts is Modulated by Varying Serum Concentrations in the Medium

The Journal of Poultry Science, 2007
The influence of varying leucine and fetal calf serum (FCS) concentrations in the culture medium on protein synthesis and degradation of chicken embryo myoblasts was examined.
Mai Oki, Hiroyuki Sato, Kazuki Nakagawa, Kazumi Kita   +3 more
doaj   +1 more source

Influence of Valine Analogues on Protein Synthesis of Chicken Embryo Myoblasts

The Journal of Poultry Science, 2014
The influence of various valine analogues on protein synthesis of chicken embryo myoblasts was examined. Valine and its analogues (D-valine, methylvaline, valinol) were supplemented into Medium 199 containing 20 ng/ml of chicken insulin-like growth ...
Kazumi Kita, Ryosuke Makino
doaj   +1 more source

MiR-34b-5p Mediates the Proliferation and Differentiation of Myoblasts by Targeting IGFBP2

Cells, 2019
As key post-transcriptional regulators, microRNAs (miRNAs) play an indispensable role in skeletal muscle development. Our previous study suggested that miR-34b-5p and IGFBP2 could have a potential role in skeletal muscle growth. Our goal in this study is
Zhijun Wang, Xiaocui Zhang, Zhenhui Li, Bahareldin Ali Abdalla, Yangfeng Chen, Qinghua Nie   +5 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source