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Heat stress inhibits the proliferation and differentiation of myoblasts and is associated with damage to mitochondria

open access: yesFrontiers in Cell and Developmental Biology, 2023
Introduction: Heat stress is harmful to the health of humans and animals, more and more common, as a consequence of global warming, while the mechanism that heat stress modulates skeletal development remains unknown.
Jiawei Lu, Huixia Li, Debing Yu
exaly   +3 more sources

Epigenetics of Genes Displaying High and Preferential Expression in Myoblasts [PDF]

open access: yesEpigenomes
Background/Objectives: Genome-wide studies of differential DNA methylation often focus on its role in turning transcription on or off. Here we report some atypical epigenetic/transcription relationships for 92 genes that are highly and preferentially ...
Kenneth C. Ehrlich   +3 more
doaj   +2 more sources

Transcription of Endogenous Retrovirus Group K Members and Their Neighboring Genes in Chicken Skeletal Muscle Myoblasts

open access: yesThe Journal of Poultry Science, 2021
Skeletal muscle myoblasts are myogenic precursor cells that generate myofibers during muscle development and growth. We recently reported that broiler myoblasts, compared to layer myoblasts, proliferate and differentiate more actively and promptly into ...
Tomohide Takaya   +3 more
doaj   +1 more source

Isolation and culturing myogenic satellite cells from ovine skeletal muscle [PDF]

open access: yesThe Iranian Journal of Veterinary Science and Technology, 2020
Sheep satellite cells more than satellite cells of the rat and mouse are similar to human satellite cells. These cells are widely used in the modeling and treatment of diseases like heart insufficiency, neurological diseases, muscular dystrophy, cerebral
Zahra Rashidian   +3 more
doaj   +1 more source

The importance of intermediate filaments in the shape maintenance of myoblast model tissues

open access: yeseLife, 2022
Liquid and elastic behaviours of tissues drive their morphology and response to the environment. They appear as the first insight into tissue mechanics.
Irène Nagle   +5 more
doaj   +1 more source

Inflammatory Caspase Activity Mediates HMGB1 Release and Differentiation in Myoblasts Affected by Peripheral Arterial Disease

open access: yesCells, 2022
Introduction: We previously showed that caspase-1 and -11, which are activated by inflammasomes, mediate recovery from muscle ischemia in mice. We hypothesized that similar to murine models, inflammatory caspases modulate myogenicity and inflammation in ...
Ricardo Ferrari   +14 more
doaj   +1 more source

Nitric Oxide Trickle Drives Heme into Hemoglobin and Muscle Myoglobin

open access: yesCells, 2022
Ever since the days of NO being proclaimed as the “molecule of the year”, the molecular effects of this miracle gas on the globins have remained elusive.
Mamta P. Sumi, Blair Tupta, Arnab Ghosh
doaj   +1 more source

Schwann Cells Promote Myogenic Differentiation of Myoblasts and Adipogenic Mesenchymal Stromal Cells on Poly-ɛ-Caprolactone-Collagen I-Nanofibers

open access: yesCells, 2022
For the purpose of skeletal muscle tissue engineering, different cell types have been investigated regarding their myogenic differentiation potential, including co-cultured myoblasts and adipogenic mesenchymal stromal cells (Mb/ADSC).
Aijia Cai   +7 more
doaj   +1 more source

The effects of temperature and donor piglet age on the transcriptomic profile and energy metabolism of myoblasts

open access: yesFrontiers in Physiology, 2022
Rapid climate change is associated with frequent extreme heat events and the resulting thermal stress has consequences for the health, welfare, and growth of farm animals.
Katharina Metzger   +4 more
doaj   +1 more source

Overexpression of Kif1A in the Developing Drosophila Heart Causes Valvar and Contractility Defects: Implications for Human Congenital Heart Disease

open access: yesJournal of Cardiovascular Development and Disease, 2020
Left-sided congenital heart defects (CHDs) are among the most common forms of congenital heart disease, but a disease-causing gene has only been identified in a minority of cases.
Takeshi Akasaka   +5 more
doaj   +1 more source

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