Results 41 to 50 of about 54,075 (312)

Multilineage Differentiation for Formation of Innervated Skeletal Muscle Fibers from Healthy and Diseased Human Pluripotent Stem Cells

open access: yesCells, 2020
Induced pluripotent stem cells (iPSCs) obtained by reprogramming primary somatic cells have revolutionized the fields of cell biology and disease modeling.
Kilian Mazaleyrat   +14 more
doaj   +1 more source

Oxidative stress induces apoptosis in myoblasts.

open access: yes, 2013
(A) Viability of the myoblasts and myotubes upon GOx treatment determined by MTT assay. Viability of untreated, control myoblasts and myotubes was set as 1.
Dillon K. Walker (459087)   +6 more
core   +1 more source

Mechanically Spatio‐Chimeric Fibrin Assembly Enables Vascular‐Integrated Muscle Reconstruction for Volumetric Muscle Loss Repair

open access: yesAdvanced Materials, EarlyView.
SPARC (spatio‐chimeric, plasma‐based, anisotropic, and shear‐responsive construct) that integrates myogenic and vascular microenvironments within a single construct. The dual‐modulus matrix directs aligned myotube formation and endothelial network development, enabling a vascularized muscle implant that seamlessly anastomoses with host tissue and ...
Su Hyun Jung   +6 more
wiley   +1 more source

Myoblasts in strained fibrin gels.

open access: yes, 2013
a) Myoblasts patterning in a strained fibrin gel (Bar: 100 µm). b) The alignment of randomly selected cells was determined by using image-analysis software (Bar: 200 µm). c) Nuclear staining of myoblasts in a strained fibrin gel.
Taiji Sohmura (36540)   +5 more
core   +1 more source

Tunable 3D‐Printed Static Mixers for Gradient Bioprinting With High Cell Viability

open access: yesAdvanced Materials Technologies, EarlyView.
ABSTRACT The fabrication of native tissue‐like structures with gradual transitions in material properties, cell types, and growth factors remains a major challenge in biofabrication due to the lack of suitable methods. Mimicking the hierarchical organization of living tissues is essential for functional models, yet creating gradient, multimaterial ...
Florian Hofmann   +9 more
wiley   +1 more source

Tmod3 Phosphorylation Mediates AMPK-Dependent GLUT4 Plasma Membrane Insertion in Myoblasts

open access: yesFrontiers in Endocrinology, 2021
Insulin and muscle contractions mediate glucose transporter 4 (GLUT4) translocation and insertion into the plasma membrane (PM) for glucose uptake in skeletal muscles.
Man Mohan Shrestha   +5 more
doaj   +1 more source

Topography‐Regulated Screening Platform for Myoblast Contact Guidance

open access: yesAdvanced Materials Technologies, EarlyView.
This study develops a topography‐regulated screening platform (12 gradients in 96‐topography‐well plate) enabling analysis of skeletal muscle morphogenesis. The topography‐induced cell morphology changed, cell polarization, and myotube differentiation, establishing an evaluative framework for generating pathologically relevant myotube phenotypes to ...
Tianqi Feng   +6 more
wiley   +1 more source

Trypanosoma cruzi Promotes Transcriptomic Remodeling of the JAK/STAT Signaling and Cell Cycle Pathways in Myoblasts

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
Chagas disease is responsible for more than 10,000 deaths per year and about 6 to 7 million infected people worldwide. In its chronic stage, patients can develop mega-colon, mega-esophagus, and cardiomyopathy.
Lindice M. Nisimura   +10 more
doaj   +1 more source

Immunostaining of myoblasts (MB), and myoblasts and myotubes (MB-MT).

open access: yes, 2013
(40×magnification) from one FSHD patient and one healthy control. Desmin (red), cyclin A1 (green), Hoechst (blue) staining. Cyclin A1 was detected in nuclei of myoblasts and myotubes derived from both FSHD patients and healthy controls.
Anja Mähler (309952)   +10 more
core   +1 more source

Additive‐Manufactured, Multifunctional Bioreactor Technology for Dynamic Culture of 3D Bioprinted Tissue Models

open access: yesAdvanced Materials Technologies, EarlyView.
We introduce an additively manufactured bioreactor with a perfusion flow system and integrated temperature and pH sensors for skeletal muscle tissue biofabrication. The bioreactor's performance was evaluated by assessing the viability, spreading of the myoblast cells in a printed scaffold, and contraction of the isolated murine musculi interossei ...
Lys Sprenger   +9 more
wiley   +1 more source

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