Results 61 to 70 of about 79,103 (214)
Medical SciencesPurpose: Stress urinary incontinence (SUI) is a significant medical challenge affecting substantial parts of modern societies. Several studies suggested that cell therapy may alleviate the symptoms.
Niklas Harland +6 more
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Aligned electrospun polymer fibres for skeletal muscle regeneration [PDF]
European Cells & Materials, 2010 Skeletal muscle repair is often overlooked in surgical procedures and in serious burn victims. Creating a tissue-engineered skeletal muscle would not only provide a grafting material for these clinical situations, but could also be used as a valuable ...
KJ Aviss, JE Gough, S Downes
doaj
LKB1 Destabilizes Microtubules in Myoblasts and Contributes to Myoblast Differentiation
PLoS ONE, 2012 Skeletal muscle myoblast differentiation and fusion into multinucleate myotubes is associated with dramatic cytoskeletal changes. We find that microtubules in differentiated myotubes are highly stabilized, but premature microtubule stabilization blocks differentiation.
Isma Mian +5 more
openaire +4 more sources
Normal myoblast fusion requires myoferlin [PDF]
Development, 2005 Muscle growth occurs during embryonic development and continues in adult life as regeneration. During embryonic muscle growth and regeneration in mature muscle, singly nucleated myoblasts fuse to each other to form myotubes. In muscle growth, singly nucleated myoblasts can also fuse to existing large,syncytial myofibers as a mechanism of increasing ...
Katherine R, Doherty +7 more
openaire +2 more sources
Sestrins are evolutionarily conserved mediators of exercise benefits. [PDF]
, 2020 Exercise is among the most effective interventions for age-associated mobility decline and metabolic dysregulation. Although long-term endurance exercise promotes insulin sensitivity and expands respiratory capacity, genetic components and pathways ...
Brooks, Susan V +14 more
core +2 more sources
Akirin1 promotes myoblast differentiation by modulating multiple myoblast differentiation factors
Bioscience Reports, 2019 Abstract Akirin1 is found to be involved in myoblast differentiation. However, the mechanism by which the Akirin1 gene regulates myoblast differentiation still remains unclear. In the present study, we found that ectopic expression of Akirin1 promoted myoblast differentiation by increasing the expression of myogenic regulatory factor ...
Wenqiang Sun +9 more
openaire +2 more sources
Bioengineering & Translational MedicineA multifunctional bioreactor was fabricated in this study to investigate the facilitation efficiency of electrical and mechanical stimulations on myogenic differentiation.
Wei‐Wen Hu +4 more
doaj +1 more source
Interaction between mouse macrophages RAW264.7 and myoblasts C2C12 in a co-culture system
Di-san junyi daxue xuebao, 2019 Objective To establish a co-culture system to observe the interactions between mouse macrophage RAW264.7 and myoblast C2C12 cells. Methods RAW264.7 and C2C12 cell lines were co-cultured in a Transwell chamber containing conditioned medium for myogenic ...
LUO We +5 more
doaj +1 more source
The Stat3-Fam3a axis promotes muscle stem cell myogenic lineage progression by inducing mitochondrial respiration. [PDF]
, 2019 Metabolic reprogramming is an active regulator of stem cell fate choices, and successful stem cell differentiation in different compartments requires the induction of oxidative phosphorylation.
Cunningham, Thomas J +9 more
core +3 more sources
Prostaglandin binding activity and myoblast fusion in aggregates of avian myoblasts
Developmental Biology, 1986 Myoblast aggregates provide a system for studying cell interactions which have several advantages over standard, stationary cultures. In gyrotory rotation, aggregate size can be controlled and is independent of cell migration. In muscle aggregates, fibroblasts are excluded, yet myoblast differentiation and fusion occur in a highly synchronous fashion ...
R E, Hausman +5 more
openaire +2 more sources