Results 11 to 20 of about 79,103 (214)

Wet-Spun Trojan Horse Cell Constructs for Engineering Muscle

open access: yesFrontiers in Chemistry, 2020
Engineering of 3D regenerative skeletal muscle tissue constructs (skMTCs) using hydrogels containing muscle precursor cells (MPCs) is of potential benefit for repairing Volumetric Muscle Loss (VML) arising from trauma (e.g., road/industrial accident, war
Anita F. Quigley   +16 more
doaj   +1 more source

Heat stress inhibits the proliferation and differentiation of myoblasts and is associated with damage to mitochondria

open access: yesFrontiers in Cell and Developmental Biology, 2023
Introduction: Heat stress is harmful to the health of humans and animals, more and more common, as a consequence of global warming, while the mechanism that heat stress modulates skeletal development remains unknown.
Jiawei Lu   +5 more
doaj   +1 more source

Mechanisms of action of hESC-secreted proteins that enhance human and mouse myogenesis. [PDF]

open access: yes, 2014
Adult stem cells grow poorly in vitro compared to embryonic stem cells, and in vivo stem cell maintenance and proliferation by tissue niches progressively deteriorates with age.
CONBOY, Irina M   +6 more
core   +3 more sources

Premature senescence in primary muscle cultures of myotonic dystrophy type 2 is not associated with p16 induction

open access: yesEuropean Journal of Histochemistry, 2014
Myotonic dystrophy type 1 (DM1) and type 2 (DM2) are multisystemic disorders linked to two different genetic loci and characterized by several features including myotonia, muscle weakness and atrophy, cardiac dysfunctions, cataracts and insulin ...
L.V. Renna   +6 more
doaj   +1 more source

Hox Genes Regulate Muscle Founder Cell Pattern Autonomously and Regulate Morphogenesis Through Motor Neurons [PDF]

open access: yes, 2010
The differentiation of myoblasts to form functional muscle fibers is a consequence of interactions between the mesoderm and ectoderm. The authors examine the role of segment identity in directing these interactions by studying the role of Hox genes in ...
Dutta, Devkanya   +4 more
core   +1 more source

Lysophosphatidylcholine induces arachidonic acid release and calcium overload in cardiac myoblastic H9c2 cells

open access: yesJournal of Lipid Research, 1999
Lysophosphatidylcholine (lyso-PC) and arachidonate are products of phosphatidylcholine hydrolysis by phospholipase A2. In this study, the modulation of arachidonate release by exogenous lyso-PC in rat heart myoblastic H9c2 cells was examined.
Leonard S. Golfman   +6 more
doaj   +1 more source

Four and a half LIM protein 1C (FHL1C) [PDF]

open access: yes, 2011
Four-and-a-half LIM domain protein 1 isoform A (FHL1A) is predominantly expressed in skeletal and cardiac muscle. Mutations in the FHL1 gene are causative for several types of hereditary myopathies including X-linked myopathy with postural muscle atrophy
Binder, Josepha   +11 more
core   +1 more source

A Poglut1 mutation causes a muscular dystrophy with reduced Notch signaling and satellite cell loss [PDF]

open access: yes, 2016
Skeletal muscle regeneration by muscle satellite cells is a physiological mechanism activated upon muscle damage and regulated by Notch signaling. In a family with autosomal recessive limbgirdle muscular dystrophy, we identified a missense mutation in ...
Cabrera Serrano, Macarena   +5 more
core   +1 more source

Abelson tyrosine-protein kinase 2 regulates myoblast proliferation and controls muscle fiber length

open access: yeseLife, 2017
Muscle fiber length is nearly uniform within a muscle but widely different among different muscles. We show that Abelson tyrosine-protein kinase 2 (Abl2) has a key role in regulating myofiber length, as a loss of Abl2 leads to excessively long myofibers ...
Jennifer K Lee   +2 more
doaj   +1 more source

Circ-ZNF609 regulates G1-S progression in rhabdomyosarcoma [PDF]

open access: yes, 2019
Circular RNAs (circRNAs) represent a class of covalently closed RNAs, derived from non-canonical splicing events, which are expressed in all eukaryotes and often conserved among different species.
Bozzoni, Irene   +9 more
core   +1 more source

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