Results 11 to 20 of about 54,075 (312)
Overexpression of connexin 43 using a retroviral vector improves electrical coupling of skeletal myoblasts with cardiac myocytes
BMC Cardiovascular Disorders, 2006 Background Organ transplantation is presently often the only available option to repair a damaged heart. As heart donors are scarce, engineering of cardiac grafts from autologous skeletal myoblasts is a promising novel therapeutic strategy.
Kienast Yvonne +9 more
doaj +2 more sources
Wet-Spun Trojan Horse Cell Constructs for Engineering Muscle
Frontiers in Chemistry, 2020 Engineering of 3D regenerative skeletal muscle tissue constructs (skMTCs) using hydrogels containing muscle precursor cells (MPCs) is of potential benefit for repairing Volumetric Muscle Loss (VML) arising from trauma (e.g., road/industrial accident, war
Anita F. Quigley +16 more
doaj +1 more source
Isolation, culturing and 3D bioprinting of equine myoblasts
, 2022 Isolating and culturing myoblasts is essential for techniques such as tissue regeneration and in vitro meat production. This research describes a protocol to isolate primary myoblasts from skeletal muscle of an adult horse.
Abyzova, Maria +6 more
core +1 more source
Myoblast fusion in Drosophila [PDF]
Experimental Cell Research, 2010 The body wall musculature of a Drosophila larva is composed of an intricate pattern of 30 segmentally repeated muscle fibers in each abdominal hemisegment. Each muscle fiber has unique spatial and behavioral characteristics that include its location, orientation, epidermal attachment, size and pattern of innervation.
Shruti, Haralalka, Susan M, Abmayr
openaire +2 more sources
European Journal of Histochemistry, 2014 Myotonic dystrophy type 1 (DM1) and type 2 (DM2) are multisystemic disorders linked to two different genetic loci and characterized by several features including myotonia, muscle weakness and atrophy, cardiac dysfunctions, cataracts and insulin ...
L.V. Renna +6 more
doaj +1 more source
Journal of Lipid Research, 1999 Lysophosphatidylcholine (lyso-PC) and arachidonate are products of phosphatidylcholine hydrolysis by phospholipase A2. In this study, the modulation of arachidonate release by exogenous lyso-PC in rat heart myoblastic H9c2 cells was examined.
Leonard S. Golfman +6 more
doaj +1 more source
Abelson tyrosine-protein kinase 2 regulates myoblast proliferation and controls muscle fiber length
eLife, 2017 Muscle fiber length is nearly uniform within a muscle but widely different among different muscles. We show that Abelson tyrosine-protein kinase 2 (Abl2) has a key role in regulating myofiber length, as a loss of Abl2 leads to excessively long myofibers ...
Jennifer K Lee +2 more
doaj +1 more source
SNAI1 target genes in myoblasts [PDF]
, 2021 SNAI proteins are zinc finger transcription factors that act as transcriptional repressors through a conserved domain (SNAG domain) located in the N-terminus of the protein.
Elia, Ines
core +1 more source
Correction of the FSHD myoblast differentiation defect by fusion with healthy myoblasts [PDF]
Journal of Cellular Physiology, 2015 Facioscapulohumeral dystrophy (FSHD) is a neuromuscular disease with a prevalence that could reach 1 in 8,000 characterized by progressive asymmetric muscle weakness. Myoblasts isolated from FSHD muscles exhibit morphological differentiation defects and show a distinct transcription profile.
Dib, Carla +8 more
openaire +3 more sources
Fusion of Normoxic- and Hypoxic-Preconditioned Myoblasts Leads to Increased Hypertrophy
Cells, 2022 Injuries, high altitude, and endurance exercise lead to hypoxic conditions in skeletal muscle and sometimes to hypoxia-induced local tissue damage. Thus, regenerative myoblasts/satellite cells are exposed to different levels and durations of partial ...
Tamara Pircher +5 more
doaj +1 more source