Results 1 to 10 of about 291,391 (311)

Culture conditions influence satellite cell activation and survival of single myofibers [PDF]

open access: yesEuropean Journal of Translational Myology, 2018
Single myofiber isolation protocols allow to obtain an in vitro system in which the physical association between the myofiber and its stem cells, the satellite cells, is adequately preserved.
Alessandra Renzini   +5 more
doaj   +3 more sources

Avian Satellite Cell Plasticity [PDF]

open access: yesAnimals, 2020
Adult myogenesis is dependent on a population of precursor cells, located between the sarcolemma and the basal lamina of the muscle fiber. These satellite cells, usually present in a quiescent state, become activated in response to mechanical muscle strain, differentiating and fusing to add new nuclei to enlarging muscles.
Maurycy Jankowski   +4 more
openaire   +3 more sources

ApoE isoform does not influence skeletal muscle regeneration in adult mice

open access: yesFrontiers in Physiology, 2023
Introduction: Apolipoprotein E (ApoE) has been shown to be necessary for proper skeletal muscle regeneration. Consistent with this finding, single-cell RNA-sequencing analyses of skeletal muscle stem cells (MuSCs) revealed that Apoe is a top marker of ...
Benjamin I. Burke   +20 more
doaj   +1 more source

Implantation of Decellularized Extracellular Matrix with Resistance Training Effectively Repairs a Volumetric Muscle Loss [PDF]

open access: yes운동과학, 2022
PURPOSE Skeletal muscle has remarkable regenerative capacity in most minor injuries induced by mechanical laceration, overstretching, and toxins. However, volumetric muscle loss (VML) injury, a large volume of muscle loss beyond the self-repair capacity,
Kwangjun Lee   +2 more
doaj   +1 more source

Single cell analysis reveals satellite cell heterogeneity for proinflammatory chemokine expression

open access: yesFrontiers in Cell and Developmental Biology, 2023
Background: The expression of proinflammatory signals at the site of muscle injury are essential for efficient tissue repair and their dysregulation can lead to inflammatory myopathies.
Alexander B. Andre   +11 more
doaj   +1 more source

Myofibre Hypertrophy in the Absence of Changes to Satellite Cell Content Following Concurrent Exercise Training in Young Healthy Men

open access: yesFrontiers in Physiology, 2021
Concurrent exercise training has been suggested to create an ‘interference effect,’ attenuating resistance training-based skeletal muscle adaptations, including myofibre hypertrophy.
Baubak Shamim   +2 more
doaj   +1 more source

The Many Roles of Macrophages in Skeletal Muscle Injury and Repair

open access: yesFrontiers in Cell and Developmental Biology, 2022
Skeletal muscle is essential to physical activity and energy metabolism. Maintaining intact functions of skeletal muscle is crucial to health and wellbeing.
Xingyu Wang, Lan Zhou
doaj   +1 more source

HDAC4 regulates satellite cell proliferation and differentiation by targeting P21 and Sharp1 genes [PDF]

open access: yes, 2018
Skeletal muscle exhibits a high regenerative capacity, mainly due to the ability of satellite cells to replicate and differentiate in response to appropriate stimuli. Epigenetic control is effective at different stages of this process.
Adamo, Sergio   +9 more
core   +2 more sources

Muscle Satellite Cell Heterogeneity and Self-Renewal

open access: yesFrontiers in Cell and Developmental Biology, 2014
Adult skeletal muscle possesses extraordinary regeneration capacities. After muscle injury or exercise, large numbers of newly formed muscle fibers are generated within a week as a result of expansion and differentiation of a self-renewing pool of muscle
Norio eMotohashi, Atsushi eAsakura
doaj   +1 more source

Filopodia powered by class x myosin promote fusion of mammalian myoblasts

open access: yeseLife, 2021
Skeletal muscle fibers are multinucleated cellular giants formed by the fusion of mononuclear myoblasts. Several molecules involved in myoblast fusion have been discovered, and finger-like projections coincident with myoblast fusion have also been ...
David W Hammers   +7 more
doaj   +1 more source

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