Results 1 to 10 of about 80,080 (219)
Extracellular matrix: Brick and mortar in the skeletal muscle stem cell niche
Frontiers in Cell and Developmental Biology, 2022 The extracellular matrix (ECM) is an interconnected macromolecular scaffold occupying the space between cells. Amongst other functions, the ECM provides structural support to tissues and serves as a microenvironmental niche that conveys regulatory ...
Svenja C. Schüler +6 more
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c-Abl Kinase Is Required for Satellite Cell Function Through Pax7 Regulation
Frontiers in Cell and Developmental Biology, 2021 Satellite cells (SCs) are tissue-specific stem cells responsible for adult skeletal muscle regeneration and maintenance. SCs function is critically dependent on two families of transcription factors: the paired box (Pax) involved in specification and ...
Fabián Montecino +6 more
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eLife, 2022 Sustained exposure to a young systemic environment rejuvenates aged organisms and promotes cellular function. However, due to the intrinsic complexity of tissues it remains challenging to pinpoint niche-independent effects of circulating factors on ...
Omid Mashinchian +16 more
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The Resistance Training Effects on Skeletal Muscle Stem Cells in Older Adult: A Systematic Review and Meta-Analysis [PDF]
Cell Journal, 2023 The objective of this systematic review and meta-analysis is to examine the effects of resistance exercise trainingon muscle stem cells in older adults.
Diaco Heidari +3 more
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Cells, 2021 Muscle stem cells (MuSCs) are essential for muscle growth, maintenance and repair. Over the past decade, experiments in Drosophila have been instrumental in understanding the molecular and cellular mechanisms regulating MuSCs (also known as adult muscle ...
Hadi Boukhatmi
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Muscle Physiopathology in Parathyroid Hormone Disorders
Frontiers in Medicine, 2021 Parathyroid hormone disorders are a group of diseases in which secretion of parathormone (PTH) is impaired. The disorders that result are characterized by signs and symptoms associated with the persistent presence of high blood calcium levels ...
Cecilia Romagnoli, Maria Luisa Brandi
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CELLULAR AND MOLECULAR MECHANISMS OF MUSCLE REGENERATION
Khyber Medical University Journal, 2021 BACKGROUND: Muscle injuries are a common manifestation of exercise and non-mechanical factors such as drugs, genetic defects, and systemic diseases. Despite their clinical importance, the cellular and molecular mechanisms of muscle injury and repair are ...
Rizwan Qaisar
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Muscle Satellite Cell Heterogeneity and Self-Renewal
Frontiers in Cell and Developmental Biology, 2014 Adult skeletal muscle possesses extraordinary regeneration capacities. After muscle injury or exercise, large numbers of newly formed muscle fibers are generated within a week as a result of expansion and differentiation of a self-renewing pool of muscle
Norio eMotohashi, Atsushi eAsakura
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Culture conditions influence satellite cell activation and survival of single myofibers
European Journal of Translational Myology, 2018 Single myofiber isolation protocols allow to obtain an in vitro system in which the physical association between the myofiber and its stem cells, the satellite cells, is adequately preserved.
Alessandra Renzini +5 more
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Frontiers in Physiology, 2022 Several scientific evidence have shown that exposure to microgravity has a significant impact on the health of the musculoskeletal system by altering the expression of proteins and molecules involved in bone–muscle crosstalk, which is also observed in ...
Ida Cariati +18 more
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