Results 31 to 40 of about 90,927 (310)
Emerging gene editing strategies for Duchenne muscular dystrophy targeting stem cells
Frontiers in Physiology, 2014 The progressive loss of muscle mass characteristic of many muscular dystrophies impairs the efficacy of most of the gene and molecular therapies currently being pursued for the treatment of those disorders.
Carmen eBertoni
doaj +1 more source
, 2009 Pax3 and Pax7 are paired-box transcription factors with roles in developmental and adult regenerative myogenesis. Pax3 and Pax7 are expressed by postnatal satellite cells or their progeny but are down regulated during myogenic differentiation.
Morgan, JE +25 more
core +1 more source
Sphingosine 1-phosphate axis: a new leader actor in skeletal muscle biology
Frontiers in Physiology, 2013 Sphingosine 1-phosphate (S1P) is a bioactive lipid involved in the regulation of biological processes such as proliferation, differentiation, motility and survival. Here we review the role of S1P in the biology and homeostasis of skeletal muscle.
Chiara eDonati +5 more
doaj +1 more source
The Role of Satellite Cells in Skeletal Muscle Regeneration—The Effect of Exercise and Age
Biology, 2021 The population of satellite cells (mSCs) is highly diversified. The cells comprising it differ in their ability to regenerate their own population and differentiate, as well as in the properties they exhibit.
Agnieszka Kaczmarek +6 more
doaj +1 more source
Advances in vascular endothelial cell-mediated regulation of satellite cell repair and regeneration
Inflammation and RegenerationWith advancing age, vascular endothelial cells (ECs) exhibit functional decline and reduced angiogenic capacity, adversely affecting muscle homeostasis.
Chunyan Yang +6 more
doaj +1 more source
Muscle stem cells contribute to long‐term tissue repletion following surgical sepsis
Journal of Cachexia, Sarcopenia and Muscle, 2023 Background Over the past decade, advances in sepsis identification and management have resulted in decreased sepsis mortality. This increase in survivorship has highlighted a new clinical obstacle: chronic critical illness (CCI), for which there are no ...
Rebecca E. Schmitt +5 more
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
, 2000 Distinct glial cell types of the vertebrate peripheral nervous system (PNS) are derived from the neural crest. Here we show that the expression of the Ets domain transcription factor Erm distinguishes satellite glia from Schwann cells beginning early in ...
Mercader Huber, Nadia +13 more
core +1 more source
Positional changes of pericentromeric heterochromatin and nucleoli in postmitotic Purkinje cells during murine cerebellum development [PDF]
, 2004 Previous studies revealed changes of pericentromeric heterochromatin arrangements in postmitotic Purkinje cells (PCs) during postnatal development in the mouse cerebellum (Manuelidis, 1985; Martou and De Boni, 2000). Here, we performed vibratome sections
Knoth, R. +4 more
core +1 more source
Histological analysis of the medial gastrocnemius muscle in young healthy children
Frontiers in PhysiologyIntroductionHistological data on muscle fiber size and proportion in (very) young typically developing (TD) children is not well documented and data on capillarization and satellite cell content are also lacking.AimsThis study investigated the ...
Anke Andries +18 more
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