Results 1 to 10 of about 2,447,382 (163)
Skeletal Muscle Regeneration in Cardiotoxin-Induced Muscle Injury Models
International Journal of Molecular Sciences, 2022 Skeletal muscle injuries occur frequently in daily life and exercise. Understanding the mechanisms of regeneration is critical for accelerating the repair and regeneration of muscle. Therefore, this article reviews knowledge on the mechanisms of skeletal
Yu-Jian Liu, Jianqiang Lu
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Cell Metabolism, 2020 Summary Endothelial cell (EC)-derived signals contribute to organ regeneration, but angiocrine metabolic communication is not described. We found that EC-specific loss of the glycolytic regulator pfkfb3 reduced ischemic hindlimb revascularization and ...
Andrea Banfi +2 more
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Cell MetabolismDiabetes represents a major public health concern with a considerable impact on human life and healthcare expenditures. It is now well established that diabetes is characterized by a severe skeletal muscle pathology that limits functional capacity and ...
Niels Jessen +2 more
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Skeletal muscle regeneration is modulated by inflammation
Journal of Orthopaedic Translation, 2018 Skeletal muscle regeneration is a complex process orchestrated by multiple steps. Recent findings indicate that inflammatory responses could play central roles in bridging initial muscle injury responses and timely muscle injury reparation.
Wenjun Yang, Ping Hu
doaj +3 more sources
Methods for Accurate Assessment of Myofiber Maturity During Skeletal Muscle Regeneration
Frontiers in Cell and Developmental Biology, 2020 Adult skeletal muscle has a remarkable ability to regenerate. Regeneration of mature muscle fibers is dependent on muscle stem cells called satellite cells.
Yuki Yoshimoto +4 more
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Stem Cell Aging in Skeletal Muscle Regeneration and Disease
International Journal of Molecular Sciences, 2020 Skeletal muscle comprises 30–40% of the weight of a healthy human body and is required for voluntary movements in humans. Mature skeletal muscle is formed by multinuclear cells, which are called myofibers.
Shinsuke Yuasa +2 more
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Pax7 reporter mouse models: a pocket guide for satellite cell research
European Journal of Translational Myology, 2023 Since their discovery, satellite cells have showcased their need as primary contributors to skeletal muscle maintenance and repair. Satellite cells lay dormant, but when needed, activate, differentiate, fuse to fibres and self-renew, that has bestowed ...
Huascar Pedro Ortuste Quiroga +2 more
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Senescence atlas reveals an aged-like inflamed niche that blunts muscle regeneration
Nature, 2022 Tissue regeneration requires coordination between resident stem cells and local niche cells^ 1 , 2 . Here we identify that senescent cells are integral components of the skeletal muscle regenerative niche that repress regeneration at all stages of life ...
V. Moiseeva +21 more
semanticscholar +1 more source
An in vitro Mechanical Damage Model of Isolated Myofibers in a Floating Culture Condition
Bio-Protocol, 2022 Muscle stem cells (satellite cells), located on the surface of myofibers, are rapidly activated from a quiescent state following skeletal muscle injury.
Yoshifumi Tsuchiya, Yusuke Ono
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Cellular interplay in skeletal muscle regeneration and wasting: insights from animal models
Journal of Cachexia, Sarcopenia and Muscle, 2023 Skeletal muscle wasting, whether related to physiological ageing, muscle disuse or to an underlying chronic disease, is a key determinant to quality of life and mortality.
P. Henrot +8 more
semanticscholar +1 more source