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Skeletal muscle regeneration is modulated by inflammation
Journal of Orthopaedic Translation, 2018 Skeletal muscle regeneration is a complex process orchestrated by multiple steps. Recent findings indicate that inflammatory responses could play central roles in bridging initial muscle injury responses and timely muscle injury reparation.
Wenjun Yang, Ping Hu
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The role of the cGAS/STING pathway in skeletal muscle regeneration: modulation of inflammation, macrophage polarization, and oxidative stress [PDF]
Cellular & Molecular Biology LettersBackground Skeletal muscle regeneration is essential for restoring muscle structure and function following injury. This process is influenced by various signaling pathways.
Xiaoguang Liu +10 more
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Methods for Accurate Assessment of Myofiber Maturity During Skeletal Muscle Regeneration
Frontiers in Cell and Developmental Biology, 2020 Adult skeletal muscle has a remarkable ability to regenerate. Regeneration of mature muscle fibers is dependent on muscle stem cells called satellite cells.
Yuki Yoshimoto +4 more
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Pax7 reporter mouse models: a pocket guide for satellite cell research
European Journal of Translational Myology, 2023 Since their discovery, satellite cells have showcased their need as primary contributors to skeletal muscle maintenance and repair. Satellite cells lay dormant, but when needed, activate, differentiate, fuse to fibres and self-renew, that has bestowed ...
Huascar Pedro Ortuste Quiroga +2 more
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An in vitro Mechanical Damage Model of Isolated Myofibers in a Floating Culture Condition
Bio-Protocol, 2022 Muscle stem cells (satellite cells), located on the surface of myofibers, are rapidly activated from a quiescent state following skeletal muscle injury.
Yoshifumi Tsuchiya, Yusuke Ono
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A Coupled Mechanobiological Model of Muscle Regeneration In Cerebral Palsy
Frontiers in Bioengineering and Biotechnology, 2021 Cerebral palsy is a neuromusculoskeletal disorder associated with muscle weakness, altered muscle architecture, and progressive musculoskeletal symptoms that worsen with age. Pathological changes at the level of the whole muscle have been shown; however,
Stephanie Khuu +3 more
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The Role of Mitochondria in Mediation of Skeletal Muscle Repair
Muscles, 2023 Musculoskeletal health is directly linked to independence and longevity, but disease and aging impairs muscle mass and health. Complete repair after a pathological or physiological muscle injury is critical for maintaining muscle function, yet muscle ...
Stephen E. Alway +2 more
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Frontiers in Cell and Developmental Biology, 2020 Primary culture of skeletal muscle stem cells (MuSCs) is indispensable to study the dynamics of muscle regeneration and homeostasis. Here we describe the modified pre-plating method for isolating MuSCs in culture with greatly improved purity, yield, and ...
Kiyoshi Yoshioka +5 more
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Chromatin Landscape During Skeletal Muscle Differentiation
Frontiers in Genetics, 2020 Cellular commitment and differentiation involve highly coordinated mechanisms by which tissue-specific genes are activated while others are repressed. These mechanisms rely on the activity of specific transcription factors, chromatin remodeling enzymes ...
Oscar Hernández-Hernández +2 more
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SCSMRD: A database for single-cell skeletal muscle regeneration
Journal of Integrative Agriculture, 2023 Skeletal muscle regeneration is a complex process where various cell types and cytokines are involved. Single-cell RNA-sequencing (scRNA-seq) provides the opportunity to deconvolute heterogeneous tissue into individual cells based on their transcriptomic
Xi-kang FENG +4 more
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