Results 1 to 10 of about 305,195 (311)
HDAC4 Regulates Skeletal Muscle Regeneration via Soluble Factors [PDF]
Frontiers in Physiology, 2018 Skeletal muscle possesses a high ability to regenerate after an insult or in pathological conditions, relying on satellite cells, the skeletal muscle stem cells.
Alessandra Renzini +5 more
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Pax7 reporter mouse models: a pocket guide for satellite cell research
European Journal of Translational Myology, 2023 Since their discovery, satellite cells have showcased their need as primary contributors to skeletal muscle maintenance and repair. Satellite cells lay dormant, but when needed, activate, differentiate, fuse to fibres and self-renew, that has bestowed ...
Huascar Pedro Ortuste Quiroga +2 more
doaj +1 more source
An in vitro Mechanical Damage Model of Isolated Myofibers in a Floating Culture Condition
Bio-Protocol, 2022 Muscle stem cells (satellite cells), located on the surface of myofibers, are rapidly activated from a quiescent state following skeletal muscle injury.
Yoshifumi Tsuchiya, Yusuke Ono
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A Coupled Mechanobiological Model of Muscle Regeneration In Cerebral Palsy
Frontiers in Bioengineering and Biotechnology, 2021 Cerebral palsy is a neuromusculoskeletal disorder associated with muscle weakness, altered muscle architecture, and progressive musculoskeletal symptoms that worsen with age. Pathological changes at the level of the whole muscle have been shown; however,
Stephanie Khuu +3 more
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The Role of Mitochondria in Mediation of Skeletal Muscle Repair
Muscles, 2023 Musculoskeletal health is directly linked to independence and longevity, but disease and aging impairs muscle mass and health. Complete repair after a pathological or physiological muscle injury is critical for maintaining muscle function, yet muscle ...
Stephen E. Alway +2 more
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Frontiers in Cell and Developmental Biology, 2020 Primary culture of skeletal muscle stem cells (MuSCs) is indispensable to study the dynamics of muscle regeneration and homeostasis. Here we describe the modified pre-plating method for isolating MuSCs in culture with greatly improved purity, yield, and ...
Kiyoshi Yoshioka +5 more
doaj +1 more source
Chromatin Landscape During Skeletal Muscle Differentiation
Frontiers in Genetics, 2020 Cellular commitment and differentiation involve highly coordinated mechanisms by which tissue-specific genes are activated while others are repressed. These mechanisms rely on the activity of specific transcription factors, chromatin remodeling enzymes ...
Oscar Hernández-Hernández +2 more
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Muscle regeneration after sepsis [PDF]
Critical Care, 2016 Severe critical illness is often complicated by intensive care unit-acquired weakness (ICU-AW), which is associated with increased ICU and post-ICU mortality, delayed weaning from mechanical ventilation and long-term functional disability. Several mechanisms have been implicated in the pathophysiology of ICU-AW, but muscle regeneration has not been ...
Bouglé, Adrien +3 more
openaire +2 more sources
SCSMRD: A database for single-cell skeletal muscle regeneration
Journal of Integrative Agriculture, 2023 Skeletal muscle regeneration is a complex process where various cell types and cytokines are involved. Single-cell RNA-sequencing (scRNA-seq) provides the opportunity to deconvolute heterogeneous tissue into individual cells based on their transcriptomic
Xi-kang FENG +4 more
doaj +1 more source
Efferocytosis during Skeletal Muscle Regeneration [PDF]
Cells, 2021 Efferocytosis, i.e., engulfment of dead cells by macrophages, is a crucial step during tissue repair after an injury. Efferocytosis delineates the transition from the pro-inflammatory phase of the inflammatory response to the recovery phase that ensures tissue reconstruction. We present here the role of efferocytosis during skeletal muscle regeneration,
Gaëtan Juban, Bénédicte Chazaud
openaire +3 more sources