Results 31 to 40 of about 2,447,481 (262)
Cholesterol-derived glucocorticoids control early fate specification in embryonic stem cells
Stem Cell Research, 2015 Aside from its role in cell membrane integrity, cholesterol is a key component in steroid hormone production. The vital functions of steroid hormones such as estrogen, testosterone, glucocorticoids (Gcrts) and mineralocorticoids (Mnrts) in perinatal and ...
Joaquim Cabral-Teixeira +5 more
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The Role of Innate and Adaptive Immune Cells in Skeletal Muscle Regeneration
International Journal of Molecular Sciences, 2021 Skeletal muscle regeneration is highly dependent on the inflammatory response. A wide variety of innate and adaptive immune cells orchestrate the complex process of muscle repair.
N. Ziemkiewicz +3 more
semanticscholar +1 more source
The Basis of Muscle Regeneration [PDF]
Advances in Biology, 2014 Muscle regeneration recapitulates many aspects of embryonic myogenesis and is an important homeostatic process of the adult skeletal muscle, which, after development, retains the capacity to regenerate in response to appropriate stimuli, activating the muscle compartment of stem cells, namely, satellite cells, as well as other precursor cells. Moreover,
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Frontiers in Cell and Developmental Biology, 2023 Skeletal muscle has a highly regenerative capacity, but the detailed process is not fully understood. Several in vitro skeletal muscle regeneration models have been developed to elucidate this, all of which rely on specialized culture conditions that ...
Naoya Kase +4 more
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The Role of Satellite Cells in Skeletal Muscle Regeneration—The Effect of Exercise and Age
Biology, 2021 Simple Summary Studies describing the effects of various forms of exercise and age on muscle regeneration were reviewed. Satellite cells are a heterogeneous group of cells that includes stem cells and skeletal muscle progenitor cells.
A. Kaczmarek +6 more
semanticscholar +1 more source
Immunometabolism of macrophages regulates skeletal muscle regeneration
Frontiers in Cell and Developmental Biology, 2022 Sarcopenia is an age-related progressive loss of skeletal muscle mass, quality, and strength disease. In addition, sarcopenia is tightly correlated with age-associated pathologies, such as sarcopenic obesity and osteoporosis.
Yu-Fan Chen +9 more
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Journal of Cachexia, Sarcopenia and Muscle, 2021 Transmembrane proteins are vital for intercellular signalling and play important roles in the control of cell fate. However, their physiological functions and mechanisms of action in myogenesis and muscle disorders remain largely unexplored.
W. Luo +12 more
semanticscholar +1 more source
Myogenic Differentiation of Stem Cells for Skeletal Muscle Regeneration
Stem Cells International, 2021 Stem cells have become a hot research topic in the field of regenerative medicine due to their self-renewal and differentiation capabilities. Skeletal muscle tissue is one of the most important tissues in the human body, and it is difficult to recover ...
Dengjie Yu +9 more
semanticscholar +1 more source
Muscle Injuries Induce a Prostacyclin‐PPARγ/PGC1a‐FAO Spike That Boosts Regeneration
Advanced Science, 2023 It is well‐known that muscle regeneration declines with aging, and aged muscles undergo degenerative atrophy or sarcopenia. While exercise and acute injury are both known to induce muscle regeneration, the molecular signals that help trigger muscle ...
Lanfang Luo +14 more
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Extraocular Muscle Repair and Regeneration [PDF]
Current Ophthalmology Reports, 2017 The goal of this review is to summarize the unique regenerative milieu within mature mammalian extraocular muscles (EOMs). This will aid in understanding disease propensity for and sparing of EOMs in skeletal muscle diseases as well as the recalcitrance of the EOM to injury.The EOMs continually remodel throughout life and contain an extremely enriched ...
Mayank, Verma +2 more
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