Results 31 to 40 of about 1,366,391 (310)
Muscle regeneration after sepsis [PDF]
Critical Care, 2016 Severe critical illness is often complicated by intensive care unit-acquired weakness (ICU-AW), which is associated with increased ICU and post-ICU mortality, delayed weaning from mechanical ventilation and long-term functional disability. Several mechanisms have been implicated in the pathophysiology of ICU-AW, but muscle regeneration has not been ...
Bouglé, Adrien +3 more
openaire +2 more sources
EZH1 as a key mediator of exercise-induced H3K27me3 and H3K4me3 in mouse skeletal muscle
Advanced Exercise and Health ScienceEpigenetic modification is a key mechanism that enhances the response of skeletal muscle to exercise training. Exercise-induced H3K27me3, which is co-modified with H3K4me3, is crucial for gene responses and adaptation in skeletal muscle; however, how ...
Junya Shimizu +3 more
doaj +1 more source
Enhancement of skeletal muscle regeneration [PDF]
Developmental Dynamics, 1994 AbstractWe have studied the effect of adding extra satellite cells or soluble factors from crushed muscle on regeneration of minced fragments from rat tibialis muscle. The muscle mince was wrapped in an artificial epimysium to prevent adhesions and cell immigration from adjacent muscles.
R, Bischoff, C, Heintz
openaire +2 more sources
European Journal of Translational MyologyThe application of implantable biomaterials in reconstructive grafting is a common practice in surgical fields such as orthopedics, maxillary and plastic surgery.
Fernando Leiva-Cepas +5 more
doaj +1 more source
Non-coding RNAs in skeletal muscle regeneration
Non-coding RNA Research, 2017 Following injury, skeletal muscles can regenerate from muscle specific stem cells, called satellite cells. Quiescent in uninjured muscles, satellite cells become activated, proliferate and differentiate into myotubes. Muscle regeneration occurs following
Tristan J.M. Gonçalves +1 more
doaj +1 more source
Genomic profiling reveals that transient adipogenic activation is a hallmark of mouse models of skeletal muscle regeneration. [PDF]
PLoS ONE, 2013 The marbling of skeletal muscle by ectopic adipose tissue is a hallmark of many muscle diseases, including sarcopenia and muscular dystrophies, and generally associates with impaired muscle regeneration. Although the etiology and the molecular mechanisms
Laura Lukjanenko +4 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Peroxisome proliferator-activated receptor-γ coactivator-1α in muscle links metabolism to inflammation [PDF]
, 2009 1. In higher eukaryotes, metabolism and immunity are tightly coupled. However, whereas evolutionary, a compromised immune response due to undernourishment has been the predominant problem, the inflammatory response to obesity and other life style ...
Handschin, C., Handschin, C
core +1 more source
Scientific Reports, 2017 Muscle satellite cells are essential for muscle regeneration. However, efficient regeneration does not occur without muscle-resident mesenchymal progenitor cells.
Yasushi Maeda +5 more
doaj +1 more source
Mest but Not MiR-335 Affects Skeletal Muscle Growth and Regeneration. [PDF]
PLoS ONE, 2015 When skeletal muscle fibers are injured, they regenerate and grow until their sizes are adjusted to surrounding muscle fibers and other relevant organs.
Yosuke Hiramuki +4 more
doaj +1 more source