Results 31 to 40 of about 176,030 (314)

Enhancement of skeletal muscle regeneration [PDF]

Developmental Dynamics, 1994
AbstractWe have studied the effect of adding extra satellite cells or soluble factors from crushed muscle on regeneration of minced fragments from rat tibialis muscle. The muscle mince was wrapped in an artificial epimysium to prevent adhesions and cell immigration from adjacent muscles.
R, Bischoff, C, Heintz
openaire   +2 more sources

EZH1 as a key mediator of exercise-induced H3K27me3 and H3K4me3 in mouse skeletal muscle

Advanced Exercise and Health Science
Epigenetic modification is a key mechanism that enhances the response of skeletal muscle to exercise training. Exercise-induced H3K27me3, which is co-modified with H3K4me3, is crucial for gene responses and adaptation in skeletal muscle; however, how ...
Junya Shimizu, Naoki Horii, Yusuke Ono, Fuminori Kawano   +3 more
doaj   +1 more source

Mest but Not MiR-335 Affects Skeletal Muscle Growth and Regeneration. [PDF]

PLoS ONE, 2015
When skeletal muscle fibers are injured, they regenerate and grow until their sizes are adjusted to surrounding muscle fibers and other relevant organs.
Yosuke Hiramuki, Takahiko Sato, Yasuhide Furuta, M Azim Surani, Atsuko Sehara-Fujisawa   +4 more
doaj   +1 more source

Peroxisome proliferator-activated receptor-γ coactivator-1α in muscle links metabolism to inflammation [PDF]

, 2009
1. In higher eukaryotes, metabolism and immunity are tightly coupled. However, whereas evolutionary, a compromised immune response due to undernourishment has been the predominant problem, the inflammatory response to obesity and other life style ...
Handschin, C., Handschin, C
core   +1 more source

Regenerative response of rat skeletal muscle to the implantation of a collagen-based bone graft substitute: an in vivo study

European Journal of Translational Myology
The application of implantable biomaterials in reconstructive grafting is a common practice in surgical fields such as orthopedics, maxillary and plastic surgery.
Fernando Leiva-Cepas, Maria Jesus Gil-Belmonte, Ignacio Jimena, Maria Angeles Peña-Toledo, Rafael Villalba, Jose Peña-Amaro   +5 more
doaj   +1 more source

Non-coding RNAs in skeletal muscle regeneration

Non-coding RNA Research, 2017
Following injury, skeletal muscles can regenerate from muscle specific stem cells, called satellite cells. Quiescent in uninjured muscles, satellite cells become activated, proliferate and differentiate into myotubes. Muscle regeneration occurs following
Tristan J.M. Gonçalves, Anne-Sophie Armand   +1 more
doaj   +1 more source

Genomic profiling reveals that transient adipogenic activation is a hallmark of mouse models of skeletal muscle regeneration. [PDF]

PLoS ONE, 2013
The marbling of skeletal muscle by ectopic adipose tissue is a hallmark of many muscle diseases, including sarcopenia and muscular dystrophies, and generally associates with impaired muscle regeneration. Although the etiology and the molecular mechanisms
Laura Lukjanenko, Sophie Brachat, Eliane Pierrel, Estelle Lach-Trifilieff, Jerome N Feige   +4 more
doaj   +1 more source

Nicotinamide riboside kinases regulate skeletal muscle fiber-type specification and are rate-limiting for metabolic adaptations during regeneration

Frontiers in Cell and Developmental Biology, 2022
Nicotinamide riboside kinases (NRKs) control the conversion of dietary Nicotinamide Riboside (NR) to NAD+, but little is known about their contribution to endogenous NAD+ turnover and muscle plasticity during skeletal muscle growth and remodeling.
Tanja Sonntag, Tanja Sonntag, Sara Ancel, Sara Ancel, Sonia Karaz, Paulina Cichosz, Guillaume Jacot, Maria Pilar Giner, José Luis Sanchez-Garcia, Alice Pannérec, Sofia Moco, Vincenzo Sorrentino, Carles Cantó, Carles Cantó, Jérôme N. Feige, Jérôme N. Feige   +15 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The effects of inspiratory muscle training in older adults

, 2015
Purpose: Declining inspiratory muscle function and structure and systemic low-level inflammation and oxidative stress may contribute to morbidity and mortality during normal ageing.
Mills, Dean E., Dean E. Mills (16661205), Yvonne A. Barnett (16661208), Johnson, Michael A., Barnett, YA, Mills, DE, Sharpe, GR, Sharpe, Graham R., Graham R. Sharpe (16661214), Smith, William H. T., William H. T. Smith (16661211), Johnson, MA, Barnett, Yvonne A., Smith, WHT, Michael A. Johnson (1317849)   +14 more
core   +1 more source