Results 41 to 50 of about 176,030 (314)

CXCL12 and osteopontin from bone marrow-derived mesenchymal stromal cells improve muscle regeneration

Scientific Reports, 2017
Muscle satellite cells are essential for muscle regeneration. However, efficient regeneration does not occur without muscle-resident mesenchymal progenitor cells.
Yasushi Maeda, Yasuhiro Yonemochi, Yuki Nakajyo, Hideaki Hidaka, Tokunori Ikeda, Yukio Ando   +5 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

: Role of Cripto in skeletal muscle regeneration

, 2012
International audienceSkeletal muscle regeneration mainly depends on satellite cells, a population of resident muscle stem cells. However, our understanding of the molecular mechanisms underlying satellite cell activation is still largely undefined. Here,
Iaconis, S., Guardiola, Ombretta, Brunelli, Silvia, Shen, Michael, M., Touvier, Thierry, Lonardo, Enza, Iaconis, Salvatore, Cossu, Giulio, Bouche, A., Liguori, Giovanna L., Liguori, Giovanna,, Lafuste, Peggy, Shen, M., Mourikis, Philippos, Bouché, Ann, Guardiola, O., Minchiotti, Gabriella, Liguori, G., Carmeliet, Peter, Andolfi, G., Tajbakhsh, S., Minchiotti, G., de Bock, Katrien, Andolfi, Gennaro, Brunelli, S., Shen, Michael M., de Bock, K., Mourikis, P., Lonardo, E., Lafuste, P., Liguori, Giovanna, L., Shen, Michael,, Tajbakhsh, Shahragim, Touvier, T., Cossu, G., Carmeliet, P.   +35 more
core   +1 more source

Muscle regeneration is disrupted by cancer cachexia without loss of muscle stem cell potential. [PDF]

PLoS ONE, 2018
Cancer cachexia is a severe, debilitating condition characterized by progressive body wasting associated with remarkable loss of skeletal muscle weight.
Shoya Inaba, Atsushi Hinohara, Masashi Tachibana, Kazutake Tsujikawa, So-Ichiro Fukada   +4 more
doaj   +1 more source

Induction of Skeletal Muscle Injury by Intramuscular Injection of Cardiotoxin in Mouse

Bio-Protocol, 2023
Skeletal muscle is the most abundant tissue in the human body and has a tremendous capability to regenerate in response to muscle injuries and diseases. Induction of acute muscle injury is a common method to study muscle regeneration in vivo. Cardiotoxin
Xin Fu, Sheng Li, Minzhi Jia, Wenjun Yang, Ping Hu   +4 more
doaj   +1 more source

Skeletal Muscle Development and Regeneration

Stem Cells and Development, 2007
In the late stages of muscle development, a unique cell population emerges that is a key player in postnatal muscle growth and muscle regeneration. The location of these cells next to the muscle fibers triggers their designation as satellite cells. During the healing of injured muscle tissue, satellite cells are capable of forming completely new muscle
Grefte, S., Kuijpers-Jagtman, A.M., Torensma, R., Hoff, J.W. Von den   +3 more
openaire   +4 more sources

Regenerating muscle with arginine methylation [PDF]

Transcription, 2017
Protein arginine methyltransferase (PRMT) is a family of nine proteins catalyzing the methylation of arginine residues. They were recently shown to be essential for proper regeneration of skeletal muscles. However, the mechanisms triggering the methylation event, as well as how the methylated substrates regulate muscle stem cell function and fate ...
Roméo S, Blanc, Stéphane, Richard
openaire   +2 more sources

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Mitochondrial glycerol 3‐phosphate dehydrogenase promotes skeletal muscle regeneration

EMBO Molecular Medicine, 2018
While adult mammalian skeletal muscle is stable due to its post‐mitotic nature, muscle regeneration is still essential throughout life for maintaining functional fitness.
Xiufei Liu, Hua Qu, Yi Zheng, Qian Liao, Linlin Zhang, Xiaoyu Liao, Xin Xiong, Yuren Wang, Rui Zhang, Hui Wang, Qiang Tong, Zhenqi Liu, Hui Dong, Gangyi Yang, Zhiming Zhu, Jing Xu, Hongting Zheng   +16 more
doaj   +1 more source