Results 41 to 50 of about 305,195 (311)
Decellularized diaphragmatic muscle drives a constructive angiogenic response in vivo [PDF]
, 2018 Skeletal muscle tissue engineering (TE) aims to efficiently repair large congenital and acquired defects. Biological acellular scaffolds are considered a good tool for TE, as decellularization allows structural preservation of tissue extracellular matrix
Alvar\ue8z Fallas, Mario +11 more
core +4 more sources
European Journal of Translational MyologyThe application of implantable biomaterials in reconstructive grafting is a common practice in surgical fields such as orthopedics, maxillary and plastic surgery.
Fernando Leiva-Cepas +5 more
doaj +1 more source
Induction of Skeletal Muscle Injury by Intramuscular Injection of Cardiotoxin in Mouse
Bio-Protocol, 2023 Skeletal muscle is the most abundant tissue in the human body and has a tremendous capability to regenerate in response to muscle injuries and diseases. Induction of acute muscle injury is a common method to study muscle regeneration in vivo. Cardiotoxin
Xin Fu +4 more
doaj +1 more source
The role of metabolic remodeling in macrophage polarization and its effect on skeletal muscle regeneration [PDF]
, 2019 Macrophages are crucial for tissue homeostasis. Based on their activation, they might display classical/M1 or alternative/M2 phenotypes. M1 macrophages produce pro-inflammatory cytokines, reactive oxygen species (ROS), and nitric oxide (NO).
Alessio Torcinaro +13 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Scientific Reports, 2017 Muscle satellite cells are essential for muscle regeneration. However, efficient regeneration does not occur without muscle-resident mesenchymal progenitor cells.
Yasushi Maeda +5 more
doaj +1 more source
Muscle regeneration is disrupted by cancer cachexia without loss of muscle stem cell potential. [PDF]
PLoS ONE, 2018 Cancer cachexia is a severe, debilitating condition characterized by progressive body wasting associated with remarkable loss of skeletal muscle weight.
Shoya Inaba +4 more
doaj +1 more source
New insights into the epigenetic control of satellite cells [PDF]
, 2015 Epigenetics finely tunes gene expression at a functional level without modifying the DNA sequence, thereby contributing to the complexity of genomic regulation.
Adamo, Sergio +2 more
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Systemic Problems: A perspective on stem cell aging and rejuvenation. [PDF]
, 2015 This review provides balanced analysis of the advances in systemic regulation of young and old tissue stem cells and suggests strategies for accelerating development of therapies to broadly combat age-related tissue degenerative pathologies.
CONBOY, Irina M +2 more
core +6 more sources