Results 1 to 10 of about 130,952 (308)

HDAC4 Regulates Skeletal Muscle Regeneration via Soluble Factors [PDF]

Frontiers in Physiology, 2018
Skeletal muscle possesses a high ability to regenerate after an insult or in pathological conditions, relying on satellite cells, the skeletal muscle stem cells.
Alessandra Renzini, Nicoletta Marroncelli, Chiara Noviello, Viviana Moresi, Viviana Moresi, Sergio Adamo   +5 more
doaj   +5 more sources

LC-MS/MS based metabolomics reveals the mechanism of skeletal muscle regeneration [PDF]

BMC Musculoskeletal Disorders
Background Skeletal muscle possesses a robust regenerative capacity and can effectively repair itself following injury. However, research on the metabolic changes during skeletal muscle regeneration in large animals remains relatively limited. Therefore,
Lei Yi, Kaiming Wang, Sui Liufu, Wenwu Chen, Bohe Chen, Xiaolin Liu, Caihong Liu, Jingwen Liu, Xin Xu, Haiming Ma   +9 more
doaj   +2 more sources

Macrophage SREBP1 regulates skeletal muscle regeneration. [PDF]

Front Immunol, 2023
Macrophages are essential for the proper inflammatory and reparative processes that lead to regeneration of skeletal muscle after injury. Recent studies have demonstrated close links between the function of activated macrophages and their cellular metabolism.
Oishi Y, Koike H, Kumagami N, Nakagawa Y, Araki M, Taketomi Y, Miki Y, Matsuda S, Kim H, Matsuzaka T, Ozawa H, Shimano H, Murakami M, Manabe I.   +13 more
europepmc   +4 more sources

Effect of spermidine intake on skeletal muscle regeneration after chemical injury in male mice [PDF]

Physiological Reports
Skeletal muscle has a high regenerative ability and maintains homeostasis by rapidly regenerating from frequent damage caused by intense exercise or trauma. In sports, skeletal muscle damage occurs frequently due to intense exercise, so practical methods
Tomohiro Iwata, Takanaga Shirai, Kazuki Uemichi, Riku Tanimura, Tohru Takemasa   +4 more
doaj   +2 more sources

Type-2 innate signals are dispensable for skeletal muscle regeneration and pathology linked to Duchenne muscular dystrophy [PDF]

EMBO Reports
Immune responses play an integral role in skeletal muscle regeneration. In the genetically inherited muscle disease Duchenne muscular dystrophy (DMD), muscle regeneration is disrupted, leading to chronic inflammation, fibrosis, and early mortality ...
Melina Messing, Marine Theret, Michael R Hughes, Jiaqi Wu, Omar Husain Syed, Fang Fang Li, Yicong Li, Fabio M V Rossi, Kelly M McNagny   +8 more
doaj   +2 more sources

Efferocytosis during Skeletal Muscle Regeneration [PDF]

Cells, 2021
Efferocytosis, i.e., engulfment of dead cells by macrophages, is a crucial step during tissue repair after an injury. Efferocytosis delineates the transition from the pro-inflammatory phase of the inflammatory response to the recovery phase that ensures tissue reconstruction. We present here the role of efferocytosis during skeletal muscle regeneration,
Gaëtan Juban, Bénédicte Chazaud
openaire   +3 more sources

A concise in vitro model for evaluating interactions between macrophage and skeletal muscle cells during muscle regeneration

Frontiers in Cell and Developmental Biology, 2023
Skeletal muscle has a highly regenerative capacity, but the detailed process is not fully understood. Several in vitro skeletal muscle regeneration models have been developed to elucidate this, all of which rely on specialized culture conditions that ...
Naoya Kase, Yohko Kitagawa, Akihiro Ikenaka, Akira Niwa, Megumu K. Saito   +4 more
doaj   +1 more source

SCSMRD: A database for single-cell skeletal muscle regeneration

Journal of Integrative Agriculture, 2023
Skeletal muscle regeneration is a complex process where various cell types and cytokines are involved. Single-cell RNA-sequencing (scRNA-seq) provides the opportunity to deconvolute heterogeneous tissue into individual cells based on their transcriptomic
Xi-kang FENG, Chun-di XIE, Yong-yao LI, Zi-shuai WANG, Li-jing BAI   +4 more
doaj   +1 more source

Integrated design and fabrication strategies based on bioprinting for skeletal muscle regeneration: Current status and future perspectives

Materials & Design, 2023
The number of skeletal muscle injuries derived from myopathies, exercise, and trauma, is growing due to increasing sports activities in normal life of people. Skeletal muscle has a robust capacity for regeneration following injury.
Hong Ma, Fei Xing, Peiyun Yu, Jiawei Xu, Xinyu Wu, Rong Luo, Zhou Xiang, Pol Maria Rommens, Xin Duan, Ulrike Ritz   +9 more
doaj   +1 more source

Immunometabolism of macrophages regulates skeletal muscle regeneration

Frontiers in Cell and Developmental Biology, 2022
Sarcopenia is an age-related progressive loss of skeletal muscle mass, quality, and strength disease. In addition, sarcopenia is tightly correlated with age-associated pathologies, such as sarcopenic obesity and osteoporosis.
Yu-Fan Chen, Chien-Wei Lee, Hao-Hsiang Wu, Hao-Hsiang Wu, Wei-Ting Lin, Wei-Ting Lin, Oscar K. Lee, Oscar K. Lee, Oscar K. Lee, Oscar K. Lee   +9 more
doaj   +1 more source