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The number of skeletal muscle injuries derived from myopathies, exercise, and trauma, is growing due to increasing sports activities in normal life of people. Skeletal muscle has a robust capacity for regeneration following injury.
Hong Ma +9 more
doaj +3 more sources
The role of the cGAS/STING pathway in skeletal muscle regeneration: modulation of inflammation, macrophage polarization, and oxidative stress [PDF]
Background Skeletal muscle regeneration is essential for restoring muscle structure and function following injury. This process is influenced by various signaling pathways.
Xiaoguang Liu +10 more
doaj +2 more sources
Efferocytosis during Skeletal Muscle Regeneration [PDF]
Efferocytosis, i.e., engulfment of dead cells by macrophages, is a crucial step during tissue repair after an injury. Efferocytosis delineates the transition from the pro-inflammatory phase of the inflammatory response to the recovery phase that ensures tissue reconstruction. We present here the role of efferocytosis during skeletal muscle regeneration,
Benedicte Chazaud +2 more
exaly +4 more sources
LC-MS/MS based metabolomics reveals the mechanism of skeletal muscle regeneration [PDF]
Background Skeletal muscle possesses a robust regenerative capacity and can effectively repair itself following injury. However, research on the metabolic changes during skeletal muscle regeneration in large animals remains relatively limited. Therefore,
Lei Yi +9 more
doaj +2 more sources
Redox Control of Skeletal Muscle Regeneration [PDF]
Skeletal muscle shows high plasticity in response to external demand. Moreover, adult skeletal muscle is capable of complete regeneration after injury, due to the properties of muscle stem cells (MuSCs), the satellite cells, which follow a tightly regulated myogenic program to generate both new myofibers and new MuSCs for further ...
Hassane Zouhal +2 more
exaly +4 more sources
The effects of obesity on skeletal muscle regeneration
Obesity and metabolic disorders such as type 2 diabetes mellitus are accompanied by increased lipid deposition in adipose and non-adipose tissues including liver, pancreas, heart and skeletal muscle.
Dmitry eAkhmedov, Rebecca eBerdeaux
doaj +3 more sources
Effect of spermidine intake on skeletal muscle regeneration after chemical injury in male mice [PDF]
Skeletal muscle has a high regenerative ability and maintains homeostasis by rapidly regenerating from frequent damage caused by intense exercise or trauma. In sports, skeletal muscle damage occurs frequently due to intense exercise, so practical methods
Tomohiro Iwata +4 more
doaj +2 more sources
Summary: In skeletal muscle, new functions for vessels have recently emerged beyond oxygen and nutrient supply, through the interactions that vascular cells establish with muscle stem cells. Here, we demonstrate in human and mouse that endothelial cells (
Claire Latroche +14 more
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Type-2 innate signals are dispensable for skeletal muscle regeneration and pathology linked to Duchenne muscular dystrophy [PDF]
Immune responses play an integral role in skeletal muscle regeneration. In the genetically inherited muscle disease Duchenne muscular dystrophy (DMD), muscle regeneration is disrupted, leading to chronic inflammation, fibrosis, and early mortality ...
Melina Messing +8 more
doaj +2 more sources
Skeletal muscle has a highly regenerative capacity, but the detailed process is not fully understood. Several in vitro skeletal muscle regeneration models have been developed to elucidate this, all of which rely on specialized culture conditions that ...
Naoya Kase +4 more
doaj +1 more source

