Results 31 to 40 of about 130,952 (308)

Skeletal Muscle Development and Regeneration

Stem Cells and Development, 2007
In the late stages of muscle development, a unique cell population emerges that is a key player in postnatal muscle growth and muscle regeneration. The location of these cells next to the muscle fibers triggers their designation as satellite cells. During the healing of injured muscle tissue, satellite cells are capable of forming completely new muscle
Grefte, S., Kuijpers-Jagtman, A.M., Torensma, R., Hoff, J.W. Von den   +3 more
openaire   +4 more sources

Adult skeletal muscle stem cell migration is mediated by a blebbing/amoeboid mechanism [PDF]

, 2011
Adult skeletal muscle possesses a resident stem cell population called satellite cells which are responsible for tissue repair following damage. Satellite cell migration is crucial in promoting rapid tissue regeneration but is a poorly understood ...
Collins-Hooper, Henry, Dash, Philip R., Otto, Anthony, Patel, Anand, Patel, Ketan   +4 more
core   +1 more source

Smad4 restricts differentiation to promote expansion of satellite cell derived progenitors during skeletal muscle regeneration

eLife, 2016
Skeletal muscle regenerative potential declines with age, in part due to deficiencies in resident stem cells (satellite cells, SCs) and derived myogenic progenitors (MPs); however, the factors responsible for this decline remain obscure. TGFβ superfamily
Nicole D Paris, Andrew Soroka, Alanna Klose, Wenxuan Liu, Joe V Chakkalakal   +4 more
doaj   +1 more source

The CHC22 Clathrin-GLUT4 Transport Pathway Contributes to Skeletal Muscle Regeneration [PDF]

, 2013
Mobilization of the GLUT4 glucose transporter from intracellular storage vesicles provides a mechanism for insulin-responsive glucose import into skeletal muscle.
Brodsky, Frances M., Camus, Stéphane M., Esk, Christopher, Funke, Birgit H., Griffin, Christine A., Hoshino, Sachiko, Ishii, Akiko, Kucherlapati, Raju, Margeta, Marta, Ohkoshi, Norio, Rando, Thomas A., Sakamoto, Kazuho, Tamaoka, Akira, Torres, Jorge A., Vassilopoulos, Stéphane   +14 more
core   +4 more sources

Mitochondrial glycerol 3‐phosphate dehydrogenase promotes skeletal muscle regeneration

EMBO Molecular Medicine, 2018
While adult mammalian skeletal muscle is stable due to its post‐mitotic nature, muscle regeneration is still essential throughout life for maintaining functional fitness.
Xiufei Liu, Hua Qu, Yi Zheng, Qian Liao, Linlin Zhang, Xiaoyu Liao, Xin Xiong, Yuren Wang, Rui Zhang, Hui Wang, Qiang Tong, Zhenqi Liu, Hui Dong, Gangyi Yang, Zhiming Zhu, Jing Xu, Hongting Zheng   +16 more
doaj   +1 more source

Systemic Regulators of Skeletal Muscle Regeneration in Obesity [PDF]

, 2017
Skeletal muscle maintenance is a dynamic process and undergoes constant repair and regeneration. However, skeletal muscle regenerative capacity declines in obesity.
David E. Varon, Dharaniya Sakthivel, Indranil Sinha   +2 more
core   +1 more source

Functional Classification of Skeletal Muscle Networks. I. Normal Physiology [PDF]

, 2012
Extensive measurements of the parts list of human skeletal muscle through transcriptomics and other phenotypic assays offer the opportunity to reconstruct detailed functional models.
Subramaniam, Shankar, Wang, Yu, Winters, John   +2 more
core   +2 more sources

KLF4 regulates skeletal muscle development and regeneration by directly targeting P57 and Myomixer

Cell Death and Disease, 2023
Krüppel-like factor 4 (KLF4) is an evolutionarily conserved zinc finger-containing transcription factor that regulates diverse cellular processes such as cell proliferation, apoptosis, and differentiation.
Shufang Cai, Xiaoyu Wang, Rong Xu, Ziyun Liang, Qi Zhu, Meilin Chen, Zhuhu Lin, Chenggan Li, Tianqi Duo, Xian Tong, Enru Li, Zuyong He, Xiaohong Liu, Yaosheng Chen, Delin Mo   +14 more
doaj   +1 more source

Angiotensin II type 1 receptor antagonists alleviate muscle pathology in the mouse model for laminin-alpha2-deficient congenital muscular dystrophy (MDC1A) [PDF]

, 2012
BACKGROUND: Laminin-alpha2-deficient congenital muscular dystrophy (MDC1A) is a severe muscle-wasting disease for which no curative treatment is available.
Lin, Shuo, Meinen, Sarina, Ruegg, Markus A.   +2 more
core   +1 more source

Skeletal muscle regeneration in cancer cachexia [PDF]

Clinical and Experimental Pharmacology and Physiology, 2016
SummaryMuscle wasting is the most important phenotypic and clinical feature of cancer cachexia, and the principal cause of impaired physical function, fatigue, and respiratory complications. Muscle loss has been attributed to a variable combination of reduced nutritional intake and an imbalance between anabolic and catabolic processes.
Bossola, M, Marzetti, E, Rosa, F, Pacelli, F   +3 more
openaire   +3 more sources