Results 21 to 30 of about 130,952 (308)

Role of macrophages during skeletal muscle regeneration and hypertrophy—Implications for immunomodulatory strategies

open access: yesPhysiological Reports, 2022
Skeletal muscle is a plastic tissue that regenerates ad integrum after injury and adapts to raise mechanical loading/contractile activity by increasing its mass and/or myofiber size, a phenomenon commonly refers to as skeletal muscle hypertrophy.
Clara Bernard   +4 more
doaj   +1 more source

Immunology Guides Skeletal Muscle Regeneration [PDF]

open access: yesInternational Journal of Molecular Sciences, 2018
Soft tissue trauma of skeletal muscle is one of the most common side effects in surgery. Muscle injuries are not only caused by accident-related injuries but can also be of an iatrogenic nature as they occur during surgical interventions when the anatomical region of interest is exposed.
F. Sass   +6 more
openaire   +3 more sources

IFN-γ blockade after genetic inhibition of PD-1 aggravates skeletal muscle damage and impairs skeletal muscle regeneration

open access: yesCellular & Molecular Biology Letters, 2023
Background Innate immune responses play essential roles in skeletal muscle recovery after injury. Programmed cell death protein 1 (PD-1) contributes to skeletal muscle regeneration by promoting macrophage proinflammatory to anti-inflammatory phenotype ...
Shuzhao Zhuang   +4 more
doaj   +1 more source

Oxytocin is an age-specific circulating hormone that is necessary for muscle maintenance and regeneration. [PDF]

open access: yes, 2014
The regenerative capacity of skeletal muscle declines with age. Previous studies suggest that this process can be reversed by exposure to young circulation; however, systemic age-specific factors responsible for this phenomenon are largely unknown.
Chen, Robert Y   +8 more
core   +1 more source

Transferrin receptor 1 ablation in satellite cells impedes skeletal muscle regeneration through activation of ferroptosis

open access: yesJournal of Cachexia, Sarcopenia and Muscle, 2021
Background Satellite cells (SCs) are critical to skeletal muscle regeneration. Inactivation of SCs is linked to skeletal muscle loss. Transferrin receptor 1 (Tfr1) is associated with muscular dysfunction as muscle‐specific deletion of Tfr1 results in ...
Hongrong Ding   +29 more
doaj   +1 more source

Fibro-adipogenic progenitors in skeletal muscle homeostasis, regeneration and diseases

open access: yesOpen Biology, 2021
Skeletal muscle possesses a remarkable regenerative capacity that relies on the activity of muscle stem cells, also known as satellite cells. The presence of non-myogenic cells also plays a key role in the coordination of skeletal muscle regeneration ...
Thomas Molina   +2 more
doaj   +1 more source

Muscle cell‐derived cytokines in skeletal muscle regeneration [PDF]

open access: yesThe FEBS Journal, 2022
Regeneration of the mammalian adult skeletal muscle is a well‐orchestrated process regulated by multiple proteins and signalling pathways. Cytokines constitute a major class of regulators of skeletal myogenesis. It is well established that infiltrating immune cells at the site of muscle injury secrete cytokines, which play critical roles in the ...
Rachel J. Waldemer‐Streyer   +2 more
openaire   +2 more sources

Myoblast‐derived exosomes promote the repair and regeneration of injured skeletal muscle in mice

open access: yesFEBS Open Bio, 2022
When skeletal muscle is damaged, satellite cells (SCs) are activated to proliferate rapidly and fuse with the damaged muscle fibers to form new muscle fibers, thereby promoting muscle growth and remodeling and repair of trauma.
Shusen Ji   +11 more
doaj   +1 more source

Decellularized diaphragmatic muscle drives a constructive angiogenic response in vivo [PDF]

open access: yes, 2018
Skeletal muscle tissue engineering (TE) aims to efficiently repair large congenital and acquired defects. Biological acellular scaffolds are considered a good tool for TE, as decellularization allows structural preservation of tissue extracellular matrix
Alvar\ue8z Fallas, Mario   +11 more
core   +4 more sources

Epigenetic reprogramming of muscle progenitors: inspiration for clinical therapies [PDF]

open access: yes, 2015
In the context of regenerative medicine, based on the potential of stem cells to restore diseased tissues, epigenetics is becoming a pivotal area of interest.
Consalvi, Silvia   +2 more
core   +9 more sources

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