Results 11 to 20 of about 130,952 (308)

Redox Control of Skeletal Muscle Regeneration [PDF]

Antioxidants & Redox Signaling, 2017
Skeletal muscle shows high plasticity in response to external demand. Moreover, adult skeletal muscle is capable of complete regeneration after injury, due to the properties of muscle stem cells (MuSCs), the satellite cells, which follow a tightly regulated myogenic program to generate both new myofibers and new MuSCs for further needs.
Le Moal, Emmeran, Pialoux, Vincent, Juban, Gaëtan, Groussard, Carole, Zouhal, Hassane, Chazaud, Bénédicte, Mounier, Rémi   +6 more
openaire   +5 more sources

Chromatin Landscape During Skeletal Muscle Differentiation

Frontiers in Genetics, 2020
Cellular commitment and differentiation involve highly coordinated mechanisms by which tissue-specific genes are activated while others are repressed. These mechanisms rely on the activity of specific transcription factors, chromatin remodeling enzymes ...
Oscar Hernández-Hernández, Rodolfo Daniel Ávila-Avilés, J. Manuel Hernández-Hernández   +2 more
doaj   +1 more source

The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism

eLife, 2021
Skeletal muscle regeneration is regulated by coordinated activation of multiple signaling pathways. The unfolded protein response (UPR) is a major mechanism that detects and alleviates protein-folding stresses in the endoplasmic reticulum.
Anirban Roy, Meiricris Tomaz da Silva, Raksha Bhat, Kyle R Bohnert, Takao Iwawaki, Ashok Kumar   +5 more
doaj   +1 more source

Fn14 promotes myoblast fusion during regenerative myogenesis

Life Science Alliance, 2023
Genetic and molecular approaches demonstrate that Fn14 receptor–mediated signaling improves myoblast fusion during skeletal muscle regeneration in a cell-autonomous manner.
Meiricris Tomaz da Silva, Aniket S Joshi, Micah B Castillo, Tatiana E Koike, Anirban Roy, Preethi H Gunaratne, Ashok Kumar   +6 more
doaj   +1 more source

Enhancement of skeletal muscle regeneration [PDF]

Developmental Dynamics, 1994
AbstractWe have studied the effect of adding extra satellite cells or soluble factors from crushed muscle on regeneration of minced fragments from rat tibialis muscle. The muscle mince was wrapped in an artificial epimysium to prevent adhesions and cell immigration from adjacent muscles.
R, Bischoff, C, Heintz
openaire   +2 more sources

Muscle regeneration is disrupted by cancer cachexia without loss of muscle stem cell potential. [PDF]

PLoS ONE, 2018
Cancer cachexia is a severe, debilitating condition characterized by progressive body wasting associated with remarkable loss of skeletal muscle weight.
Shoya Inaba, Atsushi Hinohara, Masashi Tachibana, Kazutake Tsujikawa, So-Ichiro Fukada   +4 more
doaj   +1 more source

Stimulation of Non-canonical NF-κB Through Lymphotoxin-β-Receptor Impairs Myogenic Differentiation and Regeneration of Skeletal Muscle

Frontiers in Cell and Developmental Biology, 2021
Myogenic differentiation, muscle stem cell functionality, and regeneration of skeletal muscle are cellular processes under tight control of various signaling pathways.
Manuel Schmidt, Anja Weidemann, Christine Poser, Anne Bigot, Julia von Maltzahn   +4 more
doaj   +1 more source

Regulatory T cells in skeletal muscle repair and regeneration: recent insights

Cell Death and Disease, 2022
Skeletal muscle repair and regeneration after injury is a multi-stage process, involving a dynamic inflammatory microenvironment consisting of a complex network formed by the interaction of immune cells and their secreted cytokines.
Jianhui Wu, Bowen Ren, Daochao Wang, Hui Lin   +3 more
doaj   +1 more source

The elusive role of myostatin signaling for muscle regeneration and maintenance of muscle and bone homeostasis

Osteoporosis and Sarcopenia, 2023
Skeletal muscle is one of the leading frameworks of the musculo-skeletal system, which works in synergy with the bones. Long skeletal muscles provide stability and mobility to the human body and are primarily composed of proteins.
Akash Mitra, Rizwan Qaisar, Bipasha Bose, Shenoy P Sudheer   +3 more
doaj   +1 more source

The action of obestatin in skeletal muscle repair: stem cell expansion, muscle growth, and microenvironment remodeling [PDF]

, 2015
The development of therapeutic strategies for skeletal muscle diseases, such as physical injuries and myopathies, depends on the knowledge of regulatory signals that control the myogenic process. The obestatin/GPR39 system operates as an autocrine signal
ADAMO, Sergio, C. S. Mosteiro, D. l. Beiroa, F. F. Casanueva, I. Santos Zas, J. E. Viñuela, J. González Sánchez, J. M. Renaud, J. P. Camiña, J. Señarís, MORESI, Viviana, R. Gallego, R. Nogueiras, T. García Caballero, U. Gurriarán Rodríguez, W. Lin, Y. Pazos   +16 more
core   +1 more source