Results 11 to 20 of about 64,656 (260)

SCSMRD: A database for single-cell skeletal muscle regeneration

open access: yesJournal of Integrative Agriculture, 2023
Skeletal muscle regeneration is a complex process where various cell types and cytokines are involved. Single-cell RNA-sequencing (scRNA-seq) provides the opportunity to deconvolute heterogeneous tissue into individual cells based on their transcriptomic
Xi-kang FENG   +4 more
doaj   +1 more source

Immunometabolism of macrophages regulates skeletal muscle regeneration

open access: yesFrontiers in Cell and Developmental Biology, 2022
Sarcopenia is an age-related progressive loss of skeletal muscle mass, quality, and strength disease. In addition, sarcopenia is tightly correlated with age-associated pathologies, such as sarcopenic obesity and osteoporosis.
Yu-Fan Chen   +9 more
doaj   +1 more source

Chromatin Landscape During Skeletal Muscle Differentiation

open access: yesFrontiers in Genetics, 2020
Cellular commitment and differentiation involve highly coordinated mechanisms by which tissue-specific genes are activated while others are repressed. These mechanisms rely on the activity of specific transcription factors, chromatin remodeling enzymes ...
Oscar Hernández-Hernández   +2 more
doaj   +1 more source

The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism

open access: yeseLife, 2021
Skeletal muscle regeneration is regulated by coordinated activation of multiple signaling pathways. The unfolded protein response (UPR) is a major mechanism that detects and alleviates protein-folding stresses in the endoplasmic reticulum.
Anirban Roy   +5 more
doaj   +1 more source

Muscle regeneration is disrupted by cancer cachexia without loss of muscle stem cell potential. [PDF]

open access: yesPLoS ONE, 2018
Cancer cachexia is a severe, debilitating condition characterized by progressive body wasting associated with remarkable loss of skeletal muscle weight.
Shoya Inaba   +4 more
doaj   +1 more source

Fn14 promotes myoblast fusion during regenerative myogenesis

open access: yesLife Science Alliance, 2023
Genetic and molecular approaches demonstrate that Fn14 receptor–mediated signaling improves myoblast fusion during skeletal muscle regeneration in a cell-autonomous manner.
Meiricris Tomaz da Silva   +6 more
doaj   +1 more source

Enhancement of skeletal muscle regeneration [PDF]

open access: yesDevelopmental Dynamics, 1994
AbstractWe have studied the effect of adding extra satellite cells or soluble factors from crushed muscle on regeneration of minced fragments from rat tibialis muscle. The muscle mince was wrapped in an artificial epimysium to prevent adhesions and cell immigration from adjacent muscles.
R, Bischoff, C, Heintz
openaire   +2 more sources

Stimulation of Non-canonical NF-κB Through Lymphotoxin-β-Receptor Impairs Myogenic Differentiation and Regeneration of Skeletal Muscle

open access: yesFrontiers in Cell and Developmental Biology, 2021
Myogenic differentiation, muscle stem cell functionality, and regeneration of skeletal muscle are cellular processes under tight control of various signaling pathways.
Manuel Schmidt   +4 more
doaj   +1 more source

Regulatory T cells in skeletal muscle repair and regeneration: recent insights

open access: yesCell Death and Disease, 2022
Skeletal muscle repair and regeneration after injury is a multi-stage process, involving a dynamic inflammatory microenvironment consisting of a complex network formed by the interaction of immune cells and their secreted cytokines.
Jianhui Wu   +3 more
doaj   +1 more source

Sox15 Is Required for Skeletal Muscle Regeneration [PDF]

open access: yesMolecular and Cellular Biology, 2004
The Sox genes define a family of transcription factors that play a key role in the determination of cell fate during development. The preferential expression of the Sox15 in the myogenic precursor cells led us to suggest that the Sox15 is involved in the specification of myogenic cell lineages or in the regulation of the fusion of myoblasts to form ...
Lee, H. J.   +7 more
openaire   +3 more sources

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