Results 21 to 30 of about 176,030 (314)

Extraocular Muscle Repair and Regeneration [PDF]

open access: yesCurrent Ophthalmology Reports, 2017
The goal of this review is to summarize the unique regenerative milieu within mature mammalian extraocular muscles (EOMs). This will aid in understanding disease propensity for and sparing of EOMs in skeletal muscle diseases as well as the recalcitrance of the EOM to injury.The EOMs continually remodel throughout life and contain an extremely enriched ...
Mayank, Verma   +2 more
openaire   +2 more sources

Muscle Injuries Induce a Prostacyclin‐PPARγ/PGC1a‐FAO Spike That Boosts Regeneration

open access: yesAdvanced Science, 2023
It is well‐known that muscle regeneration declines with aging, and aged muscles undergo degenerative atrophy or sarcopenia. While exercise and acute injury are both known to induce muscle regeneration, the molecular signals that help trigger muscle ...
Lanfang Luo   +14 more
doaj   +1 more source

External physical and biochemical stimulation to enhance skeletal muscle bioengineering [PDF]

open access: yes, 2015
Cell based muscle tissue engineering carries the potential to revert the functional loss of muscle tissue caused by disease and trauma. Although muscle tissue can be bioengineered using various precursor cells, major limitations still remain.; In the ...
Handschin, Christoph   +5 more
core   +1 more source

Ginkgolide B facilitates muscle regeneration via rejuvenating osteocalcin‐mediated bone‐to‐muscle modulation in aged mice

open access: yesJournal of Cachexia, Sarcopenia and Muscle, 2023
Background The progressive deterioration of tissue–tissue crosstalk with aging causes a striking impairment of tissue homeostasis and functionality, particularly in the musculoskeletal system.
Belle Yu‐Hsuan Wang   +5 more
doaj   +1 more source

Progressive and Coordinated Mobilization of the Skeletal Muscle Niche throughout Tissue Repair Revealed by Single-Cell Proteomic Analysis

open access: yesCells, 2021
Background: Skeletal muscle is one of the only mammalian tissues capable of rapid and efficient regeneration after trauma or in pathological conditions.
Matthew Borok   +6 more
doaj   +1 more source

Myomaker is essential for muscle regeneration [PDF]

open access: yesGenes & Development, 2014
Regeneration of injured adult skeletal muscle involves fusion of activated satellite cells to form new myofibers. Myomaker is a muscle-specific membrane protein required for fusion of embryonic myoblasts, but its potential involvement in adult muscle regeneration has not been explored.
Millay, Douglas P.   +3 more
openaire   +2 more sources

The emergence of Pax7-expressing muscle stem cells during vertebrate head muscle development [PDF]

open access: yes, 2015
Pax7 expressing muscle stem cells accompany all skeletal muscles in the body and in healthy individuals, efficiently repair muscle after injury. Currently, the in vitro manipulation and culture of these cells is still in its infancy, yet muscle stem ...
Erika C. Jorge   +23 more
core   +1 more source

Non Muscle Stem Cells and Muscle Regeneration [PDF]

open access: yes, 2008
Skeletal muscle of the vertebrate embryo originates from paraxial mesoderm (somites, somitomers and prechordal cephalic mesoderm) (Christ and Ordahl 1995) and is formed in discrete steps by different classes of myogenic progenitor cells (Cossu and Biressi 2005).
G. Messina, S. Biressi, G. Cossu
openaire   +2 more sources

Injectable scaffold materials differ in their cell instructive effects on primary human myoblasts

open access: yesJournal of Tissue Engineering, 2017
Scaffolds are materials used for delivery of cells for regeneration of tissues. They support three-dimensional organization and improve cell survival.
Eva Kildall Hejbøl   +3 more
doaj   +1 more source

Modulation of caspase activity regulates skeletal muscle regeneration and function in response to vasopressin and tumor necrosis factor. [PDF]

open access: yesPLoS ONE, 2009
Muscle homeostasis involves de novo myogenesis, as observed in conditions of acute or chronic muscle damage. Tumor Necrosis Factor (TNF) triggers skeletal muscle wasting in several pathological conditions and inhibits muscle regeneration.
Viviana Moresi   +9 more
doaj   +1 more source

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