Results 11 to 20 of about 176,030 (314)

Decellularized Tissue for Muscle Regeneration [PDF]

International Journal of Molecular Sciences, 2018
Several acquired or congenital pathological conditions can affect skeletal muscle leading to volumetric muscle loss (VML), i.e., an irreversible loss of muscle mass and function. Decellularized tissues are natural scaffolds derived from tissues or organs, in which the cellular and nuclear contents are eliminated, but the tridimensional (3D) structure ...
Urciuolo A., De Coppi P.
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Inducible Rpt3, a Proteasome Component, Knockout in Adult Skeletal Muscle Results in Muscle Atrophy

Frontiers in Cell and Developmental Biology, 2020
The ubiquitin–proteasome system has the capacity to degrade polyubiquitinated proteins and plays an important role in many cellular processes. However, the role of Rpt3, a crucial proteasomal gene, has not been investigated in adult muscles in vivo ...
Yasuo Kitajima, Naoki Suzuki, Naoki Suzuki, Kiyoshi Yoshioka, Rumiko Izumi, Maki Tateyama, Maki Tateyama, Yoshitaka Tashiro, Ryosuke Takahashi, Masashi Aoki, Yusuke Ono   +10 more
doaj   +1 more source

METTL3-Mediated m6A Methylation Regulates Muscle Stem Cells and Muscle Regeneration by Notch Signaling Pathway

Stem Cells International, 2021
The Pax7+ muscle stem cells (MuSCs) are essential for skeletal muscle homeostasis and muscle regeneration upon injury, while the molecular mechanisms underlying muscle stem cell fate determination and muscle regeneration are still not fully understood ...
Yu Liang, Hui Han, Qiuchan Xiong, Chunlong Yang, Lu Wang, Jieyi Ma, Shuibin Lin, Yi-Zhou Jiang   +7 more
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PGC-1α modulates skeletal muscle regeneration by affecting immune response and satellite cell behavior [PDF]

, 2014
The benefits of exercise on wellbeing have been known to mankind for thousands of years, yet the underlying mechanisms of exercise have been explained only relatively recently.
Dinulović, Ivana
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Cholesterol-derived glucocorticoids control early fate specification in embryonic stem cells

Stem Cell Research, 2015
Aside from its role in cell membrane integrity, cholesterol is a key component in steroid hormone production. The vital functions of steroid hormones such as estrogen, testosterone, glucocorticoids (Gcrts) and mineralocorticoids (Mnrts) in perinatal and ...
Joaquim Cabral-Teixeira, Almudena Martinez-Fernandez, Wenqing Cai, Andre Terzic, Mark Mercola, Erik Willems   +5 more
doaj   +1 more source

The Basis of Muscle Regeneration [PDF]

Advances in Biology, 2014
Muscle regeneration recapitulates many aspects of embryonic myogenesis and is an important homeostatic process of the adult skeletal muscle, which, after development, retains the capacity to regenerate in response to appropriate stimuli, activating the muscle compartment of stem cells, namely, satellite cells, as well as other precursor cells. Moreover,
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A concise in vitro model for evaluating interactions between macrophage and skeletal muscle cells during muscle regeneration

Frontiers in Cell and Developmental Biology, 2023
Skeletal muscle has a highly regenerative capacity, but the detailed process is not fully understood. Several in vitro skeletal muscle regeneration models have been developed to elucidate this, all of which rely on specialized culture conditions that ...
Naoya Kase, Yohko Kitagawa, Akihiro Ikenaka, Akira Niwa, Megumu K. Saito   +4 more
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The regenerative plasticity of isolated urodele myofibers and its dependence on Msx1 [PDF]

, 2004
The conversion of multinucleate postmitotic muscle fibers to dividing mononucleate progeny cells (cellularisation) occurs during limb regeneration in salamanders, but the cellular events and molecular regulation underlying this remarkable process are not
Brockes, J.P., Cristiana P Velloso, Cristiana P Velloso (56684), Kumar, A, Yutaka Imokawa (46), Brockes, JP, Imokawa, Y., Kumar, A., Imokawa, Y, Velloso Cristiana P, Anoop Kumar, Jeremy P Brockes, Jeremy P Brockes (56685), Velloso, Cristiana, Velloso, CP, Brockes Jeremy P, Yutaka Imokawa, Anoop Kumar (44), Velloso, C.P., Kumar Anoop, Imokawa Yutaka, Brockes, J.P   +21 more
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Immunometabolism of macrophages regulates skeletal muscle regeneration

Frontiers in Cell and Developmental Biology, 2022
Sarcopenia is an age-related progressive loss of skeletal muscle mass, quality, and strength disease. In addition, sarcopenia is tightly correlated with age-associated pathologies, such as sarcopenic obesity and osteoporosis.
Yu-Fan Chen, Chien-Wei Lee, Hao-Hsiang Wu, Hao-Hsiang Wu, Wei-Ting Lin, Wei-Ting Lin, Oscar K. Lee, Oscar K. Lee, Oscar K. Lee, Oscar K. Lee   +9 more
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Angiotensin II type 1 receptor antagonists alleviate muscle pathology in the mouse model for laminin-alpha2-deficient congenital muscular dystrophy (MDC1A) [PDF]

, 2012
BACKGROUND: Laminin-alpha2-deficient congenital muscular dystrophy (MDC1A) is a severe muscle-wasting disease for which no curative treatment is available.
Meinen, Sarina, Markus A Ruegg, Ruegg, Markus A., Sarina Meinen, Shuo Lin, Lin, Shuo   +5 more
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