Results 1 to 10 of about 1,914 (180)

Non-canonical roles of Keap1/Nrf2 in regulating quiescence and early activation in adult muscle stem cells [PDF]

Nature Communications
Adult muscle satellite cells (MuSCs) are mostly quiescent in uninjured muscles under normal homeostasis. Although several mechanisms underlying quiescence maintenance are known, our understanding of the process remains incomplete.
Lifang Han, Yudan Qiu, Liangqiang He, Chuan Gao, Nan Zhou, Xinrong Fu, Jingyan Xu, Lirong Lin, Huating Wang, Shyam Biswal, Zhenguo Wu   +10 more
doaj   +2 more sources

ASB5 is a specific marker for muscle satellite cells but dispensable for skeletal muscle development and regeneration [PDF]

Skeletal Muscle
Background Skeletal muscle plays a crucial role in human life, contributing to posture, movement, nutrient storage, and body temperature regulation. Development and regeneration of skeletal muscles rely on embryonic myogenic progenitors and postnatal ...
Muhammad Asif, Stephanie N. Oprescu, Renjie Shang, Zheng Zhang, Feng Yue, Pengpeng Bi, Shihuan Kuang   +6 more
doaj   +2 more sources

TRPV2 in muscle satellite cells is crucial for skeletal muscle remodelling [PDF]

Cell Death and Disease
Skeletal muscle remodelling relies on muscle stem cells (MuSCs) for regeneration after injury and hypertrophy in response to mechanical loading. However, the mechanisms that trigger MuSC activation and proliferation remain unclear.
Yanzhu Chen, Kimiaki Katanosaka, Makoto Shibuya, Yubing Dong, Lidan Zhang, Motoi Kanagawa, So-ichiro Fukada, Keiji Naruse, Yuki Katanosaka   +8 more
doaj   +2 more sources

Enhancement of Hypoxia-Induced Autophagy via the HIF-1apha/BNIP3 Pathway Promotes Proliferation and Myogenic Differentiation of Aged Skeletal Muscle Satellite Cells [PDF]

Life
Aged skeletal muscle satellite cells (MuSCs) exhibit impaired autophagy-related activity, reduced proliferative capacity, and compromised myogenic differentiation, which collectively contribute to defective muscle regeneration during aging.
Li Zhou, Chenghao Feng, Jinrun Lin, Minghao Geng, Danni Qu, Jihao Xing, Hao Lin, Xiaoqi Ma, Ryosuke Nakanishi, Noriaki Maeshige, Hiroyo Kondo, Hidemi Fujino   +11 more
doaj   +2 more sources

The Development of Prenatal Muscle Satellite Cells (MuSCs) and Their Epigenetic Modifications During Skeletal Muscle Development in Yak Fetus

Biology
To investigate prenatal muscle satellite cell (MuSC) development and the associated epigenetic modifications in yak. Here, we conducted morphological and protein co-localization analyses of fetal longissimus dorsi muscle at various developmental stages ...
Guoxiong Nan, Wei Peng, Shangrong Xu, Guowen Wang, Jun Zhang   +4 more
exaly   +3 more sources

Exercise/Resistance Training and Muscle Stem Cells [PDF]

Endocrinology and Metabolism, 2021
Skeletal muscle has attracted attention as endocrine organ, because exercise-dependent cytokines called myokines/exerkines are released from skeletal muscle and are involved in systemic functions.
So-ichiro Fukada, Ayasa Nakamura
doaj   +1 more source

Gli1 marks a sentinel muscle stem cell population for muscle regeneration

Nature Communications, 2023
Adult skeletal muscle regeneration is mainly driven by muscle stem cells (MuSCs), which are highly heterogeneous. Although recent studies have started to characterize the heterogeneity of MuSCs, whether a subset of cells with distinct exists within MuSCs
Jiayin Peng, Lili Han, Biao Liu, Jiawen Song, Yuang Wang, Kunpeng Wang, Qian Guo, XinYan Liu, Yu Li, Jujin Zhang, Wenqing Wu, Sheng Li, Xin Fu, Cheng-le Zhuang, Weikang Zhang, Shengbao Suo, Ping Hu, Yun Zhao   +17 more
doaj   +1 more source

Regulation of muscle stem cell fate

Cell Regeneration, 2022
Skeletal muscle plays a critical role in human health. Muscle stem cells (MuSCs) serve as the major cell type contributing to muscle regeneration by directly differentiating to mature muscle cells.
Xin Fu, Cheng-le Zhuang, Ping Hu
doaj   +1 more source

Single-Cell Sequencing Reveals the Crosstalk Between MuSCs and FAPs in Ruminant Skeletal Muscle Development [PDF]

Cells
Hongping Zhang, , Jiazhong Guo
exaly   +2 more sources

YAP Promotes Cell Proliferation and Stemness Maintenance of Porcine Muscle Stem Cells under High-Density Condition

Cells, 2021
Muscle stem cells (MuSCs) isolated ex vivo are essential original cells to produce cultured meat. Currently, one of the main obstacles for cultured meat production derives from the limited capacity of large-scale amplification of MuSCs, especially under ...
Zheng Liu, Ling Lin, Haozhe Zhu, Zhongyuan Wu, Xi Ding, Rongrong Hu, Yichen Jiang, Changbo Tang, Shijie Ding, Renpeng Guo   +9 more
doaj   +1 more source