Results 31 to 40 of about 1,914 (180)

Drosophila, an Integrative Model to Study the Features of Muscle Stem Cells in Development and Regeneration

Cells, 2021
Muscle stem cells (MuSCs) are essential for muscle growth, maintenance and repair. Over the past decade, experiments in Drosophila have been instrumental in understanding the molecular and cellular mechanisms regulating MuSCs (also known as adult muscle ...
Hadi Boukhatmi
doaj   +1 more source

SOX6 is expressed in various cell lineages in the developing mouse heart and contributes to proper valvuloseptal development

The Anatomical Record, EarlyView.
Abstract Cells derived from the endocardium, epicardium, cardiac neural crest, and second heart field play a critical role in the formation of the valvuloseptal structures of the heart. Previous studies have shown that the expression of the transcription factor SOX9 in these cell populations is essential in the regulation of this process.
Hannah G. Tarolli, Andrew B. Harvey, Inara Devji, Raymond N. Deepe, Jenna R. Drummond, Renélyn A. Wolters, Andy Wessels   +6 more
wiley   +1 more source

Epigenetic control of myogenic identity of human muscle stem cells in Duchenne muscular dystrophy

iScience
Summary: In Duchenne muscular dystrophy (DMD), muscle stem cells’ (MuSCs) regenerative capacities are overwhelmed leading to fibrosis. Whether MuSCs have intrinsic defects or are disrupted by their environment is unclear.
Jimmy Massenet, Michèle Weiss-Gayet, Hina Bandukwala, Wilhelm Bouchereau, Stéphanie Gobert, Mélanie Magnan, Arnaud Hubas, Patrick Nusbaum, Isabelle Desguerre, Cyril Gitiaux, F. Jeffrey Dilworth, Bénédicte Chazaud   +11 more
doaj   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

Pathological hippocampal–cortical hypersynchronization disrupts memory in temporal lobe epilepsy: A multimodal intracranial electroencephalographic–functional magnetic resonance imaging study

Epilepsia, EarlyView.
Abstract Objective Memory impairment is a common comorbidity in temporal lobe epilepsy (TLE) and is thought to arise from hippocampal dysfunction and disrupted interactions within a distributed memory network involving medial temporal, frontal, and parietal cortical regions.
Ruxue Gong, Xiaolong Peng, Rebecca W. Roth, Haris Rashid, William Yun, Daniel L. Drane, Leonardo Bonilha, Lisa McTeague, Ezequiel Gleichgerrcht   +8 more
wiley   +1 more source

Protocol for the isolation of mouse muscle stem cells using fluorescence-activated cell sorting

STAR Protocols, 2023
Summary: Muscle stem cells (MuSCs) are the building blocks for regenerating skeletal muscle after trauma. If we intend to maximize the therapeutic potential of MuSCs, we must further study their molecular and functional properties.
Gabriel Elizalde, Alma Zuniga Munoz, Albert E. Almada   +2 more
doaj   +1 more source

Tele‐hospitalist services to support the opening of a new rural hospital

Journal of Hospital Medicine, EarlyView.
Abstract As rural hospitals experiencing low patient volume and workforce shortages continue to close nationally, we present an innovative telemedicine care delivery model utilized to support the opening of a new 25‐bed rural hospital in South Carolina in 2023.
Yotam Papo, Jillian Harvey, Dunc Williams Jr., Kit N. Simpson, Jay Hinesley, Allen Abernethy, Dee W. Ford, Marc Heincelman   +7 more
wiley   +1 more source

Species variations in muscle stem cell-mediated immunosuppression on T cells

Scientific Reports
Muscle stem cells (MuSCs) are effective in treating inflammatory diseases driven by overactive innate immune responses, such as colitis and acute lung injury, due to their immunomodulatory properties.
Shisong Liu, Pengbo Hou, Weijia Zhang, Muqiu Zuo, Zhanhong Liu, Tingting Wang, Yipeng Zhou, Wangwang Chen, Chao Feng, Bo Hu, Jiankai Fang   +10 more
doaj   +1 more source

PTPN1/2 inhibition promotes muscle stem cell differentiation in Duchenne muscular dystrophy

Life Science Alliance
Our study identifies PTPN1/2 as potential therapeutic targets for Duchenne muscular dystrophy and suggests the use of PTPN1/2 inhibitors to enhance the myogenic function of DMD muscle stem cells.
Yiyang Liu, Shulei Li, Rebecca Robertson, Jules A Granet, Isabelle Aubry, Romina L Filippelli, Michel L Tremblay, Natasha C Chang   +7 more
doaj   +1 more source

Maxillomandibular Advancement Outcomes in Obstructive Sleep Apnea by Age and Gender

The Laryngoscope, EarlyView.
This systematic review and meta‐analysis of 36 studies (608 patients) found that maxillomandibular advancement significantly improves polysomnographic, cephalometric, and subjective measures of obstructive sleep apnea across both sexes and throughout the lifespan. Odds of surgical cure decline roughly 3% per year of age.
Matthew O. Herbst, Lucas C. Licaj, Ethan M. Kallenberger, Shaun A. Nguyen, Courtney Chou, Allen Huang, Emily A. Brennan, Mohamed Abdelwahab   +7 more
wiley   +1 more source