Results 21 to 30 of about 1,914 (180)

Functionally heterogeneous human satellite cells identified by single cell RNA sequencing

open access: yeseLife, 2020
Although heterogeneity is recognized within the murine satellite cell pool, a comprehensive understanding of distinct subpopulations and their functional relevance in human satellite cells is lacking.
Emilie Barruet   +10 more
doaj   +1 more source

Calcitonin Receptor Signaling Inhibits Muscle Stem Cells from Escaping the Quiescent State and the Niche

open access: yesCell Reports, 2015
Calcitonin receptor (Calcr) is expressed in adult muscle stem cells (muscle satellite cells [MuSCs]). To elucidate the role of Calcr, we conditionally depleted Calcr from adult MuSCs and found that impaired regeneration after muscle injury correlated ...
Masahiko Yamaguchi   +14 more
doaj   +1 more source

The mechanosensitive ion channel PIEZO1 promotes satellite cell function in muscle regeneration

open access: yesLife Science Alliance, 2023
PIEZO1, a mechanosensitive ion channel, regulates Rho-GTPase activity and specifically accumulates at the midbody of muscle satellite cells to precisely control cell division for muscle regeneration. Muscle satellite cells (MuSCs), myogenic stem cells in
Kotaro Hirano   +17 more
doaj   +1 more source

IL4I1-catalyzed tryptophan metabolites mediate the anti-inflammatory function of cytokine-primed human muscle stem cells

open access: yesCell Death Discovery, 2023
Muscle stem cells (MuSCs) have been demonstrated to exert impressive therapeutic efficacy in disease settings through orchestrating inflammatory microenvironments.
Muqiu Zuo   +11 more
doaj   +1 more source

Mechano-signaling via Piezo1 prevents activation and p53-mediated senescence of muscle stem cells

open access: yesRedox Biology, 2022
Skeletal muscle stem cells (MuSCs), also called satellite cells, are instrumental for postnatal muscle growth and skeletal muscle regeneration. Numerous signaling cascades regulate the fate of MuSCs during muscle regeneration but the molecular mechanism ...
Yundong Peng   +7 more
doaj   +1 more source

Single-cell RNA sequencing unveils the activation of EGR1-ATF3 signaling in EGR1 + muscle stem cells during human paravertebral muscle degeneration

open access: yesMaterials & Design
Background: Paravertebral muscles (PVM) degeneration (PMD) is closely associated with low back pain. Muscle stem cells (MuSCs) can promote muscle regeneration and repair.
Yongjin Li   +8 more
doaj   +1 more source

CircUBE2Q2 promotes differentiation of cattle muscle stem cells and is a potential regulatory molecule of skeletal muscle development

open access: yesBMC Genomics, 2022
Background The growth and development of muscle stem cells (MuSCs) are significant events known to affect muscle plasticity, disease, meat production, and meat quality, which involves the types and functions of mRNA and non-coding RNA.
Rui-Men Zhang   +12 more
doaj   +1 more source

Methods to Isolate Muscle Stem Cells for Cell-Based Cultured Meat Production: A Review

open access: yesAnimals
Cultured meat production relies on various cell types, including muscle stem cells (MuSCs), embryonic stem cell lines, induced pluripotent cell lines, and naturally immortalized cell lines.
Jae-Hoon Lee   +4 more
doaj   +1 more source

Pathogenesis of the secondary contracture of musces of expression

open access: yesKazan medical journal, 1995
The role of local muscular hypertensions of muscles of expression in contracture pathogenesis is stated. Hypertensions are developed pathologically in only average extent of the nerve damage. Synkineses and hyperkineses of muscles of expression in contracture result from the formation of transversal synapse between muscles, divided by weak insulator in
G. A. Ivanichev, K. Levit
openaire   +1 more source

Oboli de Musc'

open access: yesThe English Historical Review, 1951
info:eu-repo/semantics ...
openaire   +2 more sources

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