Results 11 to 20 of about 90,927 (310)

Muscle Satellite Cell Heterogeneity and Self-Renewal

open access: yesFrontiers in Cell and Developmental Biology, 2014
Adult skeletal muscle possesses extraordinary regeneration capacities. After muscle injury or exercise, large numbers of newly formed muscle fibers are generated within a week as a result of expansion and differentiation of a self-renewing pool of muscle
Norio eMotohashi, Atsushi eAsakura
doaj   +1 more source

Culture conditions influence satellite cell activation and survival of single myofibers

open access: yesEuropean Journal of Translational Myology, 2018
Single myofiber isolation protocols allow to obtain an in vitro system in which the physical association between the myofiber and its stem cells, the satellite cells, is adequately preserved.
Alessandra Renzini   +5 more
doaj   +1 more source

PGC-1α modulates skeletal muscle regeneration by affecting immune response and satellite cell behavior [PDF]

open access: yes, 2014
The benefits of exercise on wellbeing have been known to mankind for thousands of years, yet the underlying mechanisms of exercise have been explained only relatively recently.
Dinulović, Ivana
core   +1 more source

Role of Myostatin in Muscle Degeneration by Random Positioning Machine Exposure: An in vitro Study for the Treatment of Sarcopenia

open access: yesFrontiers in Physiology, 2022
Several scientific evidence have shown that exposure to microgravity has a significant impact on the health of the musculoskeletal system by altering the expression of proteins and molecules involved in bone–muscle crosstalk, which is also observed in ...
Ida Cariati   +18 more
doaj   +1 more source

NRF2 Regulates Viability, Proliferation, Resistance to Oxidative Stress, and Differentiation of Murine Myoblasts and Muscle Satellite Cells

open access: yesCells, 2022
Increased oxidative stress can slow down the regeneration of skeletal muscle and affect the activity of muscle satellite cells (mSCs). Therefore, we evaluated the role of the NRF2 transcription factor (encoded by the Nfe2l2 gene), the main regulator of ...
Iwona Bronisz-Budzyńska   +6 more
doaj   +1 more source

Intervertebral disc herniation effects on multifidus muscle composition and resident stem cell populations

open access: yesJOR Spine, 2020
Absract Background Paraspinal muscles are crucial for vertebral stabilization and movement. These muscles are prone to develop fatty infiltration (FI), fibrosis, and atrophy in many spine conditions. Fibro‐adipogenic progenitors (FAPs), a resident muscle
Obiajulu Agha   +9 more
doaj   +1 more source

The Landscape of DNA Methylation Generates Insight Into Epigenetic Regulation of Differences Between Slow-Twitch and Fast-Twitch Muscles in Pseudocaranx dentex

open access: yesFrontiers in Marine Science, 2022
Skeletal muscles of teleost are mainly composed of slow-twitch muscles (SM) and fast-twitch muscles (FM) differed in contractile properties, metabolic capacities, and regeneration rate.
Busu Li   +9 more
doaj   +1 more source

The hypobaric hypoxia affects the oxidant balance in skeletal muscle regeneration of women

open access: yesFrontiers in Physiology, 2016
Aim: The aim of this study was to determine whether a 14-day trekking expeditions, in high altitude hypoxic environment, triggers redox disturbance at the level of satellite cells (adult stem cells) in young women.Methods: We collected muscle biopsies ...
Rosa Mancinelli   +14 more
doaj   +1 more source

The emergence of Pax7-expressing muscle stem cells during vertebrate head muscle development [PDF]

open access: yes, 2015
Pax7 expressing muscle stem cells accompany all skeletal muscles in the body and in healthy individuals, efficiently repair muscle after injury. Currently, the in vitro manipulation and culture of these cells is still in its infancy, yet muscle stem ...
Erika C. Jorge   +23 more
core   +1 more source

The PERK arm of the unfolded protein response regulates satellite cell-mediated skeletal muscle regeneration

open access: yeseLife, 2017
Regeneration of skeletal muscle in adults is mediated by satellite stem cells. Accumulation of misfolded proteins triggers endoplasmic reticulum stress that leads to unfolded protein response (UPR).
Guangyan Xiong   +7 more
doaj   +1 more source

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