Results 41 to 50 of about 291,391 (311)

Therapeutic isolation and expansion of human skeletal muscle-derived stem cells for the use of muscle-nerve-blood vessel reconstitution

Frontiers in Physiology, 2015
Skeletal muscle makes up 40-50% of body mass, and is thus considered to be a good adult stem cell source for autologous therapy. Although, several stem/progenitor cells have been fractionated from mouse skeletal muscle showing a high potential for ...
Tetsuro eTamaki, Yoshiyasu eUchiyama, Maki eHirata, Hiroyuki eHashimoto, Nobuyuki eNakajima, Kosuke eSaito, Toshiro eTerachi, Joji eMochida   +7 more
doaj   +1 more source

Membrane glucocorticoid receptors are localised in the extracellular matrix and signal through the MAPK pathway in mammalian skeletal muscle fibres [PDF]

, 2015
A number of studies have previously proposed the existence of glucocorticoid receptors on the plasma membrane of many cell types including skeletal muscle fibres.
Dietmar Steverding, Eugene Akujuru, Feliciano Protasi, Gabriel Mutungi, Goldberg AL, Lewis Arthurton, Simona Boncompagni, Timothy Pearson, Wing SS   +8 more
core   +1 more source

Advances in vascular endothelial cell-mediated regulation of satellite cell repair and regeneration

Inflammation and Regeneration
With advancing age, vascular endothelial cells (ECs) exhibit functional decline and reduced angiogenic capacity, adversely affecting muscle homeostasis.
Chunyan Yang, Liting Zhang, Lihua Liu, Lijuan Bai, Yun Liu, Ruiyun Wang, Benling Qi   +6 more
doaj   +1 more source

Glycogen Synthase Kinase 3β (GSK3β) Regulates Myogenic Differentiation in Skeletal Muscle Satellite Cells of Sheep

Animals, 2022
Glycogen synthase kinase 3β (GSK3β) has a vital role in the regulation of many cellular processes. However, the role of GSK3β in muscle cell differentiation in sheep remains unknown. In this study, we investigated the function of GSK3β in skeletal muscle
Jingquan Yang, Haosen Yang, Linjie Wang, Ping Zhou   +3 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Skeletal muscle memory: implications for sports, aging and nutrition

Frontiers in Nutrition
Observations of an enhanced hypertrophic response in previously trained muscles following periods of detraining have led researchers to propose that muscle tissue retains a form of “cellular memory”, even after returning to baseline muscle mass.
Íñigo M. Pérez-Castillo, Sergio R. Ruiz-Caride, Ricardo Rueda, José López-Chicharro, Felipe Segura-Ortiz, Hakim Bouzamondo   +5 more
doaj   +1 more source

Effects of Encapsulated Methionine on Skeletal Muscle Growth and Development and Subsequent Feedlot Performance and Carcass Characteristics in Beef Steers

Animals, 2021
Two studies were conducted to evaluate the effect of encapsulated methionine on live performance, carcass characteristics, and skeletal muscle development in feedlot steers.
Jessica O. Baggerman, Alex J. Thompson, Michael A. Jennings, Jerilyn E. Hergenreder, Whitney Rounds, Zachary K. Smith, Bradley J. Johnson   +6 more
doaj   +1 more source

Green Hybrid Satellite Terrestrial Networks: Fundamental Trade-Off Analysis [PDF]

, 2016
With the worldwide evolution of 4G generation and revolution in the information and communications technology(ICT) field to meet the exponential increase of mobile data traffic in the 2020 era, the hybrid satellite and terrestrial network based on the ...
Evans, Barry, Imran, Muhammad Ali, Wang, Wenbo, Zhang, Jiaxin, Zhang, Xing   +4 more
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Defining the Skeletal Myogenic Lineage in Human Pluripotent Stem Cell-Derived Teratomas

Cells, 2022
Skeletal muscle stem cells are essential to muscle homeostasis and regeneration after injury, and have emerged as a promising cell source for treating skeletal disorders.
Matthew P. Pappas, Ning Xie, Jacqueline S. Penaloza, Sunny S. K. Chan   +3 more
doaj   +1 more source