Results 21 to 30 of about 291,391 (311)
Suitability of a CMV/EGFP cassette to monitor stable expression from human artificial chromosomes but not transient transfer in the cells forming viable clones [PDF]
, 2004 Human artificial chromosomes (HACs) were generated by transfer of telomerized PAC constructs containing alpha satellite DNA of various human chromosomes. To monitor which cells took up constructs and subsequently formed stable clones under blasticidin S (
Christan, S. +3 more
core +1 more source
The extraocular muscle stem cell niche is resistant to ageing and disease
Frontiers in Aging Neuroscience, 2014 Specific muscles are spared in many degenerative myopathies. Most notably, the extraocular muscles (EOMs) do not show clinical signs of late stage myopathies including the accumulation of fibrosis and fat.
Luigi eFormicola +2 more
doaj +1 more source
New Perspectives for Postmortem Human Satellite Cells of Different Embryological Origin
Frontiers in Physiology, 2022 Human postmortem skeletal muscles are a unique source of satellite cells for skeletal muscle regenerative studies. Presomite and somite satellite cells obtained by postmortem muscles have been established as populations of human skeletal muscle precursor
Tiziana Pietrangelo +19 more
doaj +1 more source
Skeletal muscle regeneration and muscle progenitor cells
Journal of Physical Fitness and Sports Medicine, 2012 Skeletal muscle is the most abundant tissue in the mammalian body and is composed of multinucleated fibers that contract to generate force and movement.
Norio Motohashi +2 more
doaj +1 more source
Transplantation to study satellite cell heterogeneity in skeletal muscle
Frontiers in Cell and Developmental Biology, 2022 Skeletal muscle has a remarkable capacity to regenerate throughout life, which is mediated by its resident muscle stem cells, also called satellite cells.
Bahareh Hekmatnejad +3 more
doaj +1 more source
A requirement of Polo-like kinase 1 in murine embryonic myogenesis and adult muscle regeneration
eLife, 2019 Muscle development and regeneration require delicate cell cycle regulation of embryonic myoblasts and adult muscle satellite cells (MuSCs). Through analysis of the Polo-like kinase (Plk) family cell-cycle regulators in mice, we show that Plk1’s ...
Zhihao Jia +7 more
doaj +1 more source
Macrophage-released ADAMTS1 promotes muscle stem cell activation. [PDF]
, 2017 Coordinated activation of muscle stem cells (known as satellite cells) is critical for postnatal muscle growth and regeneration. The muscle stem cell niche is central for regulating the activation state of satellite cells, but the specific extracellular ...
Aggarwal, Abhishek +7 more
core +2 more sources
eLife, 2016 Skeletal muscle regenerative potential declines with age, in part due to deficiencies in resident stem cells (satellite cells, SCs) and derived myogenic progenitors (MPs); however, the factors responsible for this decline remain obscure. TGFβ superfamily
Nicole D Paris +4 more
doaj +1 more source
Forever young: rejuvenating muscle satellite cells [PDF]
Frontiers in Aging Neuroscience, 2015 A hallmark of aging is alteration of organismal homeostasis and progressive decline of tissue functions. Alterations of both cell intrinsic functions and regenerative environmental cues contribute to the compromised stem cell activity and reduced regenerative capability occurring in aged muscles.
Lucia eLatella +3 more
openaire +3 more sources
Myogenic potential of canine craniofacial satellite cells
Frontiers in Aging Neuroscience, 2014 The skeletal fibres have different embryological origin; the extraocular and jaw-closer muscles develop from prechordal mesoderm while the limb and trunk muscles from somites.
Rita Maria Laura La Rovere +23 more
doaj +1 more source