Results 31 to 40 of about 35,975 (260)

Akt2, a Novel Functional Link between p38 Mitogen-Activated Protein Kinase and Phosphatidylinositol 3-Kinase Pathways in Myogenesis [PDF]

open access: yes, 2004
Activation of either the phosphatidylinositol 3-kinase (PI 3-kinase)/Akt or the p38 mitogen-activated protein kinase (MAPK) signaling pathways accelerates myogenesis but only when the reciprocal pathway is functional. We therefore examined the hypothesis
Holding, C.   +15 more
core   +1 more source

Features of Fractal Conformity and Bioconsolidation in the Early Myogenesis Gene Expression and Their Relationship to the Genetic Diversity of Chicken Breeds

open access: yesAnimals, 2023
Elements of fractal analysis are widely used in scientific research, including several biological disciplines. In this study, we hypothesized that chicken breed biodiversity manifests not only at the phenotypic level, but also at the genetic-system level
Ivan I. Kochish   +8 more
doaj   +1 more source

Selection of reference genes for expression studies with fish myogenic cell cultures [PDF]

open access: yes, 2009
Background: Relatively few studies have used cell culture systems to investigate gene expression and the regulation of myogenesis in fish. To produce robust data from quantitative real-time PCR mRNA levels need to be normalised using internal reference ...
Bower, Neil I.   +3 more
core   +1 more source

Construction and Analysis of Subtractive cDNA Library of Muscular Tissue in Hybrid of Chicken-Quail Related to Myogenesis

open access: yesThe Journal of Poultry Science, 2013
Myogenesis is a complex developmental progress in which a variety of transcription factors play essential roles in regulating myogenesis. However, the genetics programs that control myogenesis molecular mechanism are poorly understood.
YaoWei Liang   +4 more
doaj   +1 more source

Transcriptome Characterization of Repressed Embryonic Myogenesis Due to Maternal Calorie Restriction

open access: yesFrontiers in Cell and Developmental Biology, 2020
Fetal malnutrition decreases skeletal myofiber number and muscle mass in neonatal mammals, which increases the risk of developing obesity and diabetes in adult life. However, the associated molecular mechanisms remain unclear.
Jun He   +8 more
doaj   +1 more source

Cyclic stretch facilitates myogenesis in C2C12 myoblasts and rescues thiazolidinedione-inhibited myotube formation

open access: yesFrontiers in Bioengineering and Biotechnology, 2016
Thiazolidinedione (TZD), a specific peroxisome proliferator-activated receptor r (PPARr) agonist, was developed to control blood glucose in diabetes patients. However, several side effects were reported that increased the risk of heart failure.
Ya-Ju eChang   +11 more
doaj   +1 more source

Histone variants in skeletal myogenesis

open access: yesEpigenetics, 2021
Histone variants regulate chromatin accessibility and gene transcription. Given their distinct properties and functions, histone varint substitutions allow for profound alteration of nucleosomal architecture and local chromatin landscape.
Nandini Karthik, Reshma Taneja
doaj   +1 more source

Molecular regulation of skeletal muscle tissue formation and development

open access: yesVeterinární Medicína, 2018
This article provides a complex overview of the different stages of myogenesis with an emphasis on the molecular, genetic and cellular bases for skeletal muscle growth.
M. Nesvadbova, G. Borilova
doaj   +1 more source

Dipyridamole activates adenosine A2B receptor and AMPK/cAMP signaling and promotes myogenic differentiation of myoblastic C2C12 cells

open access: yesFrontiers in Pharmacology, 2023
Introduction: Sarcopenia is defined as a loss of muscle mass and strength. ATP homeostasis is crucial during myogenesis. We determined how the purinergic system modulates myogenesis using dipyridamole (blocks adenosine taken up by the cells) and ...
Miguel Marco-Bonilla   +8 more
doaj   +1 more source

Circular RNAs in myogenesis

open access: yesBiochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2020
Skeletal muscles have an immense ability to regenerate from the muscle stem cells called satellite cells. The process of skeletal muscle regeneration is called myogenesis, which starts with activation of quiescent satellite cells immediately after muscle injury followed by proliferation and fusion of myoblasts into myotubes.
Arundhati, Das   +4 more
openaire   +3 more sources

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