Results 51 to 60 of about 54,460 (292)
MicroRNAs in skeletal myogenesis [PDF]
Cell Cycle, 2011 MicroRNAs (miRNAs) have emerged as critical regulators of numerous biological processes by modulating gene expression at the post-transcriptional level. It has become increasingly clear that almost all aspects of skeletal muscle development involve regulation by miRNAs.
Yejing, Ge, Jie, Chen
openaire +2 more sources
Frontiers in Bioengineering and Biotechnology, 2016 Thiazolidinedione (TZD), a specific peroxisome proliferator-activated receptor r (PPARr) agonist, was developed to control blood glucose in diabetes patients. However, several side effects were reported that increased the risk of heart failure.
Ya-Ju eChang +11 more
doaj +1 more source
Angewandte Chemie, EarlyView.Current interest in artificial cell research underscores its potential to deepen our understanding of life's fundamental processes. This review highlights advances in bottom‐up coacervate‐based artificial cell engineering via combined integration of cellular hallmarks.
Arjan Hazegh Nikroo +3 more
wiley +2 more sources
Molecular regulation of skeletal muscle tissue formation and development
Veterinární Medicína, 2018 This article provides a complex overview of the different stages of myogenesis with an emphasis on the molecular, genetic and cellular bases for skeletal muscle growth.
M. Nesvadbova, G. Borilova
doaj +1 more source
Histone variants in skeletal myogenesis
Epigenetics, 2021 Histone variants regulate chromatin accessibility and gene transcription. Given their distinct properties and functions, histone varint substitutions allow for profound alteration of nucleosomal architecture and local chromatin landscape.
Nandini Karthik, Reshma Taneja
doaj +1 more source
The myogenic kinome: protein kinases critical to mammalian skeletal myogenesis
Skeletal Muscle, 2011 Myogenesis is a complex and tightly regulated process, the end result of which is the formation of a multinucleated myofibre with contractile capability.
Knight James DR, Kothary Rashmi
doaj +1 more source
Frontiers in Pharmacology, 2023 Introduction: Sarcopenia is defined as a loss of muscle mass and strength. ATP homeostasis is crucial during myogenesis. We determined how the purinergic system modulates myogenesis using dipyridamole (blocks adenosine taken up by the cells) and ...
Miguel Marco-Bonilla +8 more
doaj +1 more source
Adaptive Myogenesis under Hypoxia [PDF]
Molecular and Cellular Biology, 2005 Previous studies have indicated that myoblasts can differentiate and repair muscle injury after an ischemic insult. However, it is unclear how hypoxia or glucose deprivation in the ischemic microenvironment affects myoblast differentiation. We have found that myogenesis can adapt to hypoxic conditions.
Zhong, Yun, Qun, Lin, Amato J, Giaccia
openaire +2 more sources
The action of obestatin in skeletal muscle repair: stem cell expansion, muscle growth, and microenvironment remodeling [PDF]
, 2015 The development of therapeutic strategies for skeletal muscle diseases, such as physical injuries and myopathies, depends on the knowledge of regulatory signals that control the myogenic process. The obestatin/GPR39 system operates as an autocrine signal
ADAMO, Sergio +16 more
core +1 more source
A novel in vitro model for the assessment of postnatal myonuclear accretion
Skeletal Muscle, 2018 Background Due to the post-mitotic nature of myonuclei, postnatal myogenesis is essential for skeletal muscle growth, repair, and regeneration. This process is facilitated by satellite cells through proliferation, differentiation, and subsequent fusion ...
Anita Kneppers +7 more
doaj +1 more source