Results 51 to 60 of about 35,975 (260)

The methyltransferases PRMT4/CARM1 and PRMT5 control differentially myogenesis in zebrafish.

PLoS ONE, 2011
In vertebrates, skeletal myogenesis involves the sequential activation of myogenic factors to lead ultimately to the differentiation into slow and fast muscle fibers.
Julie Batut, Carine Duboé, Laurence Vandel   +2 more
doaj   +1 more source

Next-generation sequencing analysis of miRNA expression in control and FSHD myogenesis. [PDF]

PLoS ONE, 2014
Emerging evidence has demonstrated that miRNA sequences can regulate skeletal myogenesis by controlling the process of myoblast proliferation and differentiation.
Veronica Colangelo, Stéphanie François, Giulia Soldà, Raffaella Picco, Francesca Roma, Enrico Ginelli, Raffaella Meneveri   +6 more
doaj   +1 more source

Loss of LCN2 Function Ameliorates Glucocorticoid‐Induced Muscle Atrophy via Remodeling the Extracellular Matrix

Advanced Science, EarlyView.
Glucocorticoids transcriptionally activate LCN2 expression via GR nuclear translocation. Secreted LCN2 binds MMP9 to degrade skeletal muscle ECM collagen, blocks integrin‐mediated mechanotransduction, bidirectionally disrupts muscle protein homeostasis, and reveals a novel target for steroid‐induced muscle atrophy.
Hongwei Shi, Xiaojing Hao, Yi Yan, Fengyang Li, Yaru Zhang, Zixin Li, Wenjuan Xie, Jiayin Lu, Xiaomao Luo, Yanjun Dong, Haidong Wang, Juan Wang   +11 more
wiley   +1 more source

The role of Sir2alpha in myogenesis

, 2003
Protein acetylation is becoming recognized as an important modification in the regulation of many cellular pathways. The silent information regulator 2 (Sir2) proteins are a family of NAD-dependent protein deacetylases. Sir2 protein function in yeast has
Abrol, Meena
core   +2 more sources

Myogenic regulatory factors Myf5 and Myod function distinctly during craniofacial myogenesis of zebrafish

, 2009
The functions of Myf5 and Myod are well known in trunk myogenesis. However, the roles that Myf5 and Myod play during craniofacial myogenesis are far from well known.
Lin, CY;Yung, RF;Lee, HC;Chen, WT;Chen, YH;Tsai, HJ, Lin, C. Y.; Yung, R. F.; Lee, H. C.; Chen, W. T.; Chen, Y. H.; Tsai, H. J., Lin, Cheng-Yung; Yung, Rong-Feng; Lee, Hung-Chieh; Chen, Wei-Ta; Chen, Yau-Hung; Tsai, Huai-Jen, 陳曜鴻; Chen, Yau-hung; Lin, C.Y.; Yung, R. F.; Lee, H. C.; Chen, W. T.; Tsai, H. J.   +3 more
core   +1 more source

Farewell to Professor David Yaffe – A Pillar of the Myogenesis Field

European Journal of Translational Myology, 2020
It is with great sadness that we have learned about the passing of Professor David Yaffe (1929-2020, Israel). Yehi Zichro Baruch - May his memory be a blessing. David was a man of family, science and nature.
Zipora Yablonka-Reuveni, Frank Stockdale, Uri Nudel, David Israeli, Helen M. Blau, Asher Shainberg, Sara Neuman, Gania Kessler-Icekson, Erica Meghid Krull, Bruce Paterson, Ora Saxel Fuchs, David Greenberg, Rachel Sarig, Orna Halevy, Eijiro Ozawa, Don J. Katcoff   +15 more
doaj   +1 more source

Overlapping functions of SIX homeoproteins during embryonic myogenesis.

PLoS Genetics, 2023
Four SIX homeoproteins display a combinatorial expression throughout embryonic developmental myogenesis and they modulate the expression of the myogenic regulatory factors.
Maud Wurmser, Rouba Madani, Nathalie Chaverot, Stéphanie Backer, Matthew Borok, Matthieu Dos Santos, Glenda Comai, Shahragim Tajbakhsh, Frédéric Relaix, Marc Santolini, Ramkumar Sambasivan, Rulang Jiang, Pascal Maire   +12 more
doaj   +1 more source

In Vivo Direct Reprogramming: Current Progress and Future Prospects from Mechanisms to Therapeutic Application

Advanced Science, EarlyView.
This review examines the potential of in vivo direct reprogramming in regenerative medicine for functional tissue restoration, highlighting the role of tissue‐resident cues in generating functionally mature reprogrammed cells from lineage‐related cells. It contains a discussion on mechanisms, reprogramming factors, delivery approaches, and applications
Rishabh Deo Singh, Mauro Calvoli, Kyeong Kyu Kim   +2 more
wiley   +1 more source

CHARACTERIZING PRMT BIOLOGY DURING MYOGENESIS [PDF]

, 2017
Despite the emerging importance of protein arginine methyltransferases (PRMTs) in regulating skeletal muscle plasticity, the biology of these enzymes during muscle development remains poorly understood. Therefore, our purpose was to investigate PRMT1, -4,
Shen, Nicole
core   +1 more source

The ESCRT-0 subcomplex component Hrs/Hgs is a master regulator of myogenesis via modulation of signaling and degradation pathways

BMC Biology, 2021
Background Myogenesis is a highly regulated process ending with the formation of myotubes, the precursors of skeletal muscle fibers. Differentiation of myoblasts into myotubes is controlled by myogenic regulatory factors (MRFs) that act as terminal ...
L. Coudert, A. Osseni, Y. G. Gangloff, L. Schaeffer, P. Leblanc   +4 more
doaj   +1 more source