Results 71 to 80 of about 32,565 (245)

Global transcriptomic analysis reveals Lnc-ADAMTS9 exerting an essential role in myogenesis through modulating the ERK signaling pathway

open access: yesJournal of Animal Science and Biotechnology, 2021
Background Long non-coding RNAs (lncRNAs) are emerging key regulators involved in a variety of biological processes such as cell differentiation and development.
Liqi Wang   +7 more
doaj   +1 more source

Review of the Molecular and Developmental Basis of Myhre Syndrome, Bench Research

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre syndrome (MS) is a connective‐tissue disorder within the acromelic dysplasia spectrum. It is characterized by congenital craniofacial, skeletal, cutaneous anomalies, respiratory, cardiovascular along with intellectual disability, deafness, and progressive fibrosis.
Camille Viaut, Valerie Cormier‐Daire
wiley   +1 more source

Elucidating the Role of BRCA1 in Skeletal Muscle Myogenesis and Function

open access: yes, 2023
The breast cancer 1 early onset gene (BRCA1) is a tumor suppressor gene susceptible to mutations associated with cancer development. We have identified that the BRCA1 gene is expressed in skeletal muscle and plays a critical role in regulating muscle ...
Koripella, Ananya   +1 more
core  

FOXO1 and GSK-3β Are Main Targets of Insulin-Mediated Myogenesis in C2C12 Muscle Cells. [PDF]

open access: yesPLoS ONE, 2016
Myogenesis and muscle hypertrophy account for muscle growth and adaptation to work overload, respectively. In adults, insulin and insulin-like growth factor 1 stimulate muscle growth, although their links with cellular energy homeostasis are not fully ...
Anna Litwiniuk   +5 more
doaj   +1 more source

Enhancing Meat Quality Through Dietary Fiber: Insights Into the Gut Microbiota‐Derived Short‐Chain Fatty Acids‐Muscle Axis

open access: yesAnimal Research and One Health, EarlyView.
Dietary fiber (DF) modulates meat quality through the gut‐muscle axis by reshaping gut microbiota, improving intestinal integrity, reducing inflammation, and regulating muscle metabolism. These mechanisms influence muscle fiber characteristics and post‐mortem biochemistry, thereby enhancing tenderness, juiciness, color, flavor, and nutritional value of
Zeshan Zulfiqar   +8 more
wiley   +1 more source

CircHOMER1 in mediating porcine skeletal muscle development

open access: yesBMC Genomics
Background Skeletal muscle serves as the principal source of high-quality protein in human nutrition. Recent studies indicate that circRNAs play key roles in myogenesis by acting as competing endogenous RNAs (ceRNAs).
Meng Li   +8 more
doaj   +1 more source

Overexpression of syndecan-4 inhibits myogenesis by regulating the expression of myogenic regulatory factors

open access: yesJournal of Animal Science and Technology
Syndecan-4, a type of heparin sulfate proteoglycan, plays an important role in muscle development, regeneration, and maintenance. Although, the important effects of syndecan-4 on the regulation of myogenesis in mice, turkeys, and bovines have been ...
Sarang Choi   +3 more
doaj   +1 more source

ZBED6 Knockout Promotes Skeletal Muscle Development in Bama Pigs by Relieving Transcriptional Repression of CDKN1A

open access: yesAnimal Research and One Health, EarlyView.
Integrated transcriptomic and functional analyses identify CDKN1A as a direct target of ZBED6 in Bama pigs. ZBED6 knockout relieves transcriptional repression of CDKN1A, thereby promoting myogenic differentiation and skeletal muscle development.
Yitian Ma   +8 more
wiley   +1 more source

CHARACTERIZING PRMT BIOLOGY DURING MYOGENESIS [PDF]

open access: yes, 2017
Despite the emerging importance of protein arginine methyltransferases (PRMTs) in regulating skeletal muscle plasticity, the biology of these enzymes during muscle development remains poorly understood. Therefore, our purpose was to investigate PRMT1, -4,
Shen, Nicole
core  

Designing the MyoFusion Media: A Serum‐Free Medium Optimized for Bovine Satellite Cell Differentiation

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Cultivated meat production requires efficient differentiation of muscle progenitor cells into myotubes without relying on animal‐derived serum, which poses ethical and scalability challenges. This study aimed to develop a chemically defined, serum‐free medium optimized for bovine satellite cell differentiation.
Aysenaz Tavsanli   +3 more
wiley   +1 more source

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