Results 91 to 100 of about 54,460 (292)

The first embryonic landscape of G-quadruplexes related to myogenesis

BMC Biology
Background DNA G-quadruplexes (G4s) represent a distinctive class of non-canonical DNA secondary structures. Despite their recognition as potential therapeutic targets in some cancers, the developmental role of G4 structures remains enigmatic.
Lijin Guo, Weiling Huang, Qi Wen, Siyu Zhang, Farhad Bordbar, Zhengzhong Xiao, Qinghua Nie   +6 more
doaj   +1 more source

Disruption of the mouse MRF4 gene identifies multiple waves of myogenesis in the myotome [PDF]

, 1995
MRF4 (herculin/Myf-6) is one of the four member MyoD family of transcription factors identified by their ability to enforce skeletal muscle differentiation upon a wide variety of nonmuscle cell types.
Miner, Jeffrey H., Patapoutian, Ardem, Stark, Kevin, Wang, Shuling, Wold, Barbara, Yoon, Jeong Kyo   +5 more
core  

Herculin, a Fourth Member of the MyoD Family of Myogenic Regulatory Genes [PDF]

, 1990
We have identified and cloned herculin, a fourth mouse muscle regulatory gene. Comparison of its DNA and deduced amino acid sequences with those of the three known myogenic genes (MyoD, myogenin, and Myf-5) reveals scattered short spans with similarity ...
Miner, Jeffrey H., Wold, Barbara J.
core   +1 more source

Chondroitin sulfate restores muscle mass via gut–muscle axis remodeling through sugar–bile acid metabolism reprogramming

iMeta, EarlyView.
The graphical abstract illustrates the molecular mechanism by which chondroitin sulfate (DCS) alleviates glucocorticoid‐induced myopathy through the gut–muscle axis. DCS selectively enriches L. johnsonii Z‐RW, enhancing bshA‐encoded BSH activity to promote bile acid deconjugation and reduce the sugar–bile acid ratio, thereby re‐establishing intestinal ...
Ruiyun Wu, Tao Wen, Nan Shang, Penghao Xie, Zhenyu Wang, Hang Li, Shaobo Li, Dequan Zhang   +7 more
wiley   +1 more source

Global transcriptomic analysis reveals Lnc-ADAMTS9 exerting an essential role in myogenesis through modulating the ERK signaling pathway

Journal of Animal Science and Biotechnology, 2021
Background Long non-coding RNAs (lncRNAs) are emerging key regulators involved in a variety of biological processes such as cell differentiation and development.
Liqi Wang, Ting He, Xin Zhang, Yubo Wang, Kai Qiu, Ning Jiao, Linjuan He, Jingdong Yin   +7 more
doaj   +1 more source

What determines growth potential and juvenile quality of farmed fish species? [PDF]

, 2013
Enhanced production of high quality and healthy fry is a key target for a successful and competitive expansion of the aquaculture industry. Although large quantities of fish larvae are produced, survival rates are often low or highly variable and growth ...
Alami-Durante, Alami-Durante, Albalat, Albors, Almuly, Almuly, Almuly, Andersen, Aragão, Ayala, Bai, Barresi, Baxendale, Betancor, Bizuayehu, Blaxter, Bodine, Booman, Bouraoui, Bouza, Bower, Bowman, Brent, Brix, Brodeur, Brooks, Buckingham, Bustin, Cade, Calduch-Giner, Calvo, Campinho, Campos, Campos, Campos, Canario, Canas, Carroll, Cerda, Cerda, Chatziplis, Chen, Chistiakov, Ciechanover, Cleveland, Cleveland, Codina, Cole, Conceição, Conceição, Conceição, Conceição, Conceição, Conceição, Cruz-Garcia, De-Santis, Delbarre-Ladrat, Devoto, Dionísio, Dong, Douglas, Douglas, Dumont, Edvardsen, Engrola, Engrola, Erbay, Fauconneau, Fauconneau, Felip, Fernandes, Fernandes, Fernandes, Fernandes, Ferraresso, Ferraresso, Focant, Franklin, Galloway, Galloway, Galloway, Garcia De La Serrana, Gibson, Goetz, Goll, Gomez-Requeni, Gomez-Requeni, Gracey, Greer-Walker, Groves, Guyon, Hagen, Hagen, Hall, Hamre, Hayes, Hietakangas, Hinits, Hollway, Houlihan, Houlihan, Houlihan, Houlihan, Houlihan, Hubert, Hurling, Infante, Jackman, Jantzen, Johnston, Johnston, Johnston, Johnston, Johnston, Johnston, Johnston, Johnston, Johnston, Johnston, Kamler, Kang, Kiørboe, Kloosterman, Koumans, Krasnov, Kuhl, Kuhl, Ladrat, Lakra, Lansard, Lecker, Liang, Link, Lopez, Lopez-Albors, Loukovitis, Louro, López-Albors, Maccatrozzo, Macqueen, Macqueen, Macqueen, Macqueen, Marschallinger, Martinez, Martinez, Martyniuk, Mascarello, Massault, Matsuoka, Merchie, Metzker, Mitter, Montserrat, Moore, Morais, Morais, Mork, Moutou, Nagasawa, Norton, Olsvik, Ostaszewska, Pajcini, Periago, Piñera, Portner, Powell, Pozios, Pérez-Sánchez, Quere, Reeds, Rehfeldt, Reid, Rescan, Rescan, Rescan, Rescan, Rowlerson, Rowlerson, Rowlerson, Roy, Roy, Saillant, Salem, Salem, Salem, Salvanes, Sanchez-Ramos, Sarropoulou, Seiliez, Seiliez, Seiliez, Shewring, Silva, Silva, Silva, Sonesson, Stears, Steinbacher, Stellabotte, Stellabotte, Stickland, Sveinsdottir, Sánchez-Ramos, Tan, Terova, Todorcevic, Valente, Valente, Valente, Veggetti, Veggetti, Vieira, Wang, Weatherley, Weil, Weinberg, West, Whitaker, Wienholds, Wienholds, Wiese, Wood, Wringe, Zane   +225 more
core   +3 more sources

The Role of Endothelin‐1 in Autoimmune Diseases: Mechanistic Insights and Therapeutic Targets

iNew Medicine, EarlyView.
The Role of Endothelin‐1 in Autoimmune Diseases. NF‐κB: nuclear factor kappa‐B; MAPK: mitogen‐activated protein kinase; PI3K: phosphoinositide 3‐kinase; ROS: reactive oxygen species; CTGF: connective tissue growth factor; TGF‐β: transforming growth factor‐β.
Xun Gong, Zhenyu Wang, Suyin Yang, Kaige Gao, Xin Yang, Min Tang   +5 more
wiley   +1 more source

FOXO1 and GSK-3β Are Main Targets of Insulin-Mediated Myogenesis in C2C12 Muscle Cells. [PDF]

PLoS ONE, 2016
Myogenesis and muscle hypertrophy account for muscle growth and adaptation to work overload, respectively. In adults, insulin and insulin-like growth factor 1 stimulate muscle growth, although their links with cellular energy homeostasis are not fully ...
Anna Litwiniuk, Barbara Pijet, Maja Pijet-Kucicka, Małgorzata Gajewska, Beata Pająk, Arkadiusz Orzechowski   +5 more
doaj   +1 more source

Generation of both an shRNA-resistant MEF2A over expression construct and a dominant negative construct in adenovirus for rescue and knockout experiments in muscle [PDF]

, 2015
The Myocyte Enhancer Factor-2, or MEF2, transcription factor family is necessary for the differentiation and regeneration of both skeletal and cardiac muscle tissue.
Comeau, Kathryn Marie
core   +1 more source

Investigating synthetic oligonucleotide targeting of miR31 in Duchenne muscular dystrophy [PDF]

, 2016
Exon-skipping via synthetic antisense oligonucleotides represents one of the most promising potential therapies for Duchenne muscular dystrophy (DMD), yet this approach is highly sequence-specific and thus each oligonucleotide is of benefit to only a ...
Hildyard, J C W, Wells, D J
core   +1 more source