Results 101 to 110 of about 32,565 (245)
Isolation, Culturing, and Differentiation of Primary Myoblasts from Skeletal Muscle of Adult Mice
Bio-Protocol, 2017 Myogenesis is a multi-step process that leads to the formation of skeletal muscle during embryonic development and repair of injured myofibers. In this process, myoblasts are the main effector cell type which fuse with each other or to injured myofibers ...
Lubna Hindi +4 more
doaj +1 more source
The FEBS Journal, EarlyView.Trim32 regulates the transition from proliferation to differentiation in C2C12 cells after myogenic induction. We found that, at the onset of differentiation, Trim32 destabilizes c‐Myc mRNA, promotes cell cycle exit, and enables normal myotube formation.
Lu Xiong +6 more
wiley +1 more source
Data_Sheet_1_Metabolic Reprogramming Promotes Myogenesis During Aging.pdf
, 2019 Sarcopenia is the age-related progressive loss of skeletal muscle mass and strength finally leading to poor physical performance. Impaired myogenesis contributes to the pathogenesis of sarcopenia, while mitochondrial dysfunctions are thought to play a ...
Maurizia Caruso (6939236) +11 more
core +1 more source
Journal of Animal Physiology and Animal Nutrition, EarlyView.ABSTRACT This study evaluated the effects of breeder hen age on the incubation performance, embryonic development, and progeny quality of Cobb500 broiler breeders at 39, 51, and 69 weeks of age. A total of 870 eggs were collected, of which 810 were incubated; these were assigned to a completely randomized design with three treatments and nine ...
Helder Freitas de Oliveira +9 more
wiley +1 more source
The Effect of Pax3 Over-expression on Myoblast Function
, 2009 The paired-box transcription factor 3 (Pax3), is a powerful myogenic regulatory factor during embryo-myogenesis. The expression of Pax3 is involved in determining somitic cell fate, resulting in the formation of the first differentiated muscle, the ...
Brijs, Erik
core
npj MicrogravityWhile the effects of microgravity on inducing skeletal muscle atrophy have been extensively studied, the impacts of microgravity on myogenesis and its mechanisms remain unclear. In this study, we developed a microphysiological system of engineered muscle
Zhanping Ren +6 more
doaj +1 more source
Veterinary and Comparative Oncology, EarlyView.ABSTRACT This study presents a comprehensive transcriptomic analysis of 128 canine mammary tumours (CMTs), aiming to characterize their molecular landscape. Differential gene expression analysis (DGE), gene set enrichment analysis (GSEA) and clustering based on the human PAM50 gene panel were applied to explore molecular differences between the ...
Ingrid Marie Moberg +8 more
wiley +1 more source
Experimental Physiology, EarlyView.Abstract Despite exercise countermeasures to sustain health and performance in spaceflight, complete maintenance of muscle mass and functions in microgravity is still not possible for most astronauts. The principal cause of the limited effectiveness of existing exercise countermeasures is the difficulty in achieving full loading forces in space.
Alessandra Bosutti +6 more
wiley +1 more source
Connective tissue fibroblasts and Tcf4 regulate myogenesis
, 2011 Muscle and its connective tissue are intimately linked in the embryo and in the adult, suggesting that interactions between these tissues are crucial for their development.
Jody M. Hansen +8 more
core +1 more source
Senolytics and exercise: Dual modalities for rejuvenating muscle
The Journal of Physiology, EarlyView.Abstract figure legend The role of senolytics on the heart and skeletal muscle. Senescent cell burden increases with ageing, disuse and disease. The senolytics dasatinib+quercetin (D+Q), navitoclax and fisetin, as well as exercise, eliminate senescent cells, reducing senescent cell burden and their senescence‐associated secretory phenotype (SASP ...
Zeynep Elif Yesilyurt‐Dirican +4 more
wiley +1 more source