Results 171 to 180 of about 9,371 (212)

Pemphigus foliaceus transforming to pemphigus vulgaris: a case report. [PDF]

Front Med (Lausanne)
Almousa MA, Kuchibhotla N, Alabdulaaly L, Couey M, Noonan V, Sroussi H.   +5 more
europepmc   +1 more source

From CAR-T to CAAR-T: redefining targeting strategies in B-cell malignancies through idiotype-directed cellular therapy. [PDF]

Front Immunol
Buczek T, Butrym A.
europepmc   +1 more source

A Subset of Pemphigus Foliaceus Patients Exhibits Pathogenic Autoantibodies Against Both Desmoglein-1 and Desmoglein-3

Journal of Investigative Dermatology, 2002
In pemphigus vulgaris the major pathogenic antibody binds desmoglein-3, and mediates mucosal disease. Development of cutaneous disease is associated with acquisition of antibodies to desmoglein-1.
Mong-Shang Lin
exaly   +3 more sources

Desmoglein 3: A Help or a Hindrance in Cancer Progression? [PDF]

Cancers, 2015
Desmoglein 3 is one of seven desmosomal cadherins that mediate cell-cell adhesion in desmosomes. Desmosomes are the intercellular junctional complexes that anchor the intermediate filaments of adjacent cells and confer strong cell adhesion thus are ...
Hong Wan
exaly   +2 more sources

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From pemphix to desmogleins

Clinics in Dermatology, 2011
In the not so distant past, the word pemphigus or pemphix was common for describing various diseases characterized by blistering as well as various disorders that do not originate from a blistering pathology. Patients with these conditions were grouped in "other" skin diseases.
Daška Štulhofer, Buzina, Branka, Marinović   +1 more
openaire   +4 more sources

Downregulation of E-cadherin and Desmoglein 1 by autocrine hepatocyte growth factor during melanoma development

Oncogene, 2001
During melanoma development, transformed cells evade keratinocyte-mediated control by downregulating cell adhesion molecules. This study investigated the regulation of cell adhesion by hepatocyte growth factor (HGF) in melanoma.
Helmut Schaider, Kapaettu Satyamoorthy, Yasushi Hanakawa   +2 more
exaly   +2 more sources

Internalization of constitutive desmogleins with the subsequent induction of desmoglein 2 in pemphigus lesions

British Journal of Dermatology, 1999
Acantholytic blisters in pemphigus vulgaris (PV) and pemphigus foliaceus (PF) are caused by a dissociation of desmosomes mediated by autoantibodies against desmoglein (Dsg) 3 and Dsg 1, respectively. The blistering occurs at the suprabasilar level in PV and at the subcorneal level in PF, which corresponds to the distribution of target antigens in the ...
K, Iwatsuki, G W, Han, R, Fukuti, M, Ohtsuka, S, Kikuchi, H, Akiba, F, Kaneko   +6 more
openaire   +2 more sources

Identification of the Ubiquitous Human Desmoglein, Dsg2, and the Expression Catalogue of the Desmoglein Subfamily of Desmosomal Cadherins

Experimental Cell Research, 1994
Desmosomes are junctions between epithelial, myocardiac, and certain other kinds of cells. They represent plasma membrane domains enriched in specific transmembrane glycoproteins, notably desmoglein (Dsg) and desmocollin (Dsc), both of which have recently been identified as members of the larger family of Ca(2+)-dependent cell adhesion molecules, the ...
S, Schäfer, P J, Koch, W W, Franke
openaire   +2 more sources

Desmoglein as a target in autoimmunity and infection

Journal of the American Academy of Dermatology, 2003
Clinical phenotypes of most diseases are complex. However, once the mechanism behind the scene is clarified, the nature shows amazing beauty. There is a simple logic behind a complex disease. The exact molecular mechanism of the blister formation in staphylococcal scalded skin syndrome (SSSS) remained to be elucidated for 3 decades since exfoliative ...
openaire   +2 more sources

Pemphigus vulgaris Antigen Is a Desmosomal Desmoglein

Dermatology, 2009
Because pemphigus vulgaris antigen (PVA) is homologous to desmogleins which are in desmosomes, we asked whether PVA is also localized to desmosomes. Immunogold electron microscopy was used to localize binding of PV antibodies. Rabbit antibodies raised against fusion proteins containing the extracellular portion of PVA bound to desmosomes of cultured ...
S, Kárpáti, M, Amagai, R, Prussick, J R, Stanley   +3 more
openaire   +2 more sources