Results 111 to 120 of about 9,938 (215)

Red Flags for Differentiating Desmosomal “Hot‐Phase” Cardiomyopathy From Acute Myocarditis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Desmosomal “hot‐phase” cardiomyopathy (HPC), characterized by bursts of myocardial inflammation mimicking acute myocarditis (AM), carries relevant risks of adverse outcomes. This study aimed to identify diagnostic “red flags” favoring HPC over
Giovanni Peretto, Nicolas Piriou, Alessio Gasperetti, Barbara Bauce, Andrea Villatore, Alessia F. Trezza, Alex Melot, Anna Palmisano, Giulia Bassetto, Marika Martini, Chiara Di Resta, Cinzia Radesich, Alessia Paldino, Maria Perotto, Eric D. Smith, Michele Ciabatti, Elisa Bruno, Monica De Gaspari, Stefania Rizzo, Kalliopi Pilichou, Antonio Esposito, Leonardo Calò, Maurizio Pieroni, Gianfranco Sinagra, Cristina Basso, Adam Helms, Paolo Della Bella, Marco Merlo   +27 more
doaj   +1 more source

Hinged plakin domains provide specialized degrees of articulation in envoplakin, periplakin and desmoplakin.

PLoS ONE, 2013
Envoplakin, periplakin and desmoplakin are cytoskeletal proteins that provide structural integrity within the skin and heart by resisting shear forces. Here we reveal the nature of unique hinges within their plakin domains that provides divergent degrees
Caezar Al-Jassar, Pau Bernadό, Martyn Chidgey, Michael Overduin   +3 more
doaj   +1 more source

Mechanical loading of desmosomes depends on the magnitude and orientation of external stress

Nature Communications, 2018
Desmosomes are intercellular adhesion complexes that connect the intermediate filament cytoskeletons of neighboring cells but direct evidence for their load-bearing nature is lacking.
Andrew J. Price, Anna-Lena Cost, Hanna Ungewiß, Jens Waschke, Alexander R. Dunn, Carsten Grashoff   +5 more
doaj   +1 more source

Desmoplakin Regulates Desmosome Hyperadhesion [PDF]

Journal of Investigative Dermatology, 2012
Hobbs, Ryan P., Green, Kathleen J.
openaire   +2 more sources

A novel desmoplakin mutation associated with left dominant arrhythmogenic cardiomyopathy and cutaneous phenotype

Hellenic Journal of Cardiology, 2021
Georgios Efthimiadis, Thomas Zegkos, Soultana Meditskou, Theodoros Karamitsos, Emmanouil Manolakos, Ioannis Papoulidis, Sandro Orru, C. Cadeddu Dessalvi, Haralambos Karvounis, Despoina Parcharidou   +9 more
doaj   +1 more source

Desmoplakin I and desmoplakin II

Journal of Biological Chemistry, 1989
E J O'Keefe, H P Erickson, V Bennett
openaire   +1 more source

The disease mutation A77V in Ryanodine receptor RyR2 induces changes in energy conduction pathways in the protein [PDF]

, 2011
Energetically responsive residues of the 217 amino acid N-terminal domain of the cardiac Ryanodine receptor RyR2 are identified by a simple elastic net model. These residues lie along a hydrogen bonded path through the protein.
Burak Erman, Nazan Walpoth
core   +1 more source

Regulation of desmocollin transcription in mouse preimplantation embryos

, 1995
The molecular mechanisms regulating the biogenesis of the first desmosomes to form during mouse embryogenesis have been studied. A sensitive modification of a reverse transcriptase-cDNA amplification procedure has been used to detect transcripts of the ...
Buxton, R.S., Collins, J.E., Fleming, T.P., Garrod, D.R., Lorimer, J.E., Pidsley, S.C.   +5 more
core  

Desmoplakin mutation underlying autosomal dominant arrhythmogenic cardiomyopathy, palmoplantar keratoderma, and curly hair

JAAD Case Reports, 2023
Colin Kincaid, BS, Luke Horton, MD, Brian Cheung, MD, Ilhan Esse, BA, Irmina Gradus-Pizlo, MD, Natasha Atanaskova Mesinkovska, MD, PhD   +5 more
doaj   +1 more source

A unique and specific interaction between alpha T-catenin and plakophilin-2 in the area composita, the mixed-type junctional structure of cardiac intercalated discs [PDF]

, 2007
Bonné, Stefan, Braet, Filip, De Rycke, Riet, Goossens, Steven, Janssens, Barbara, van Hengel, Jolanda, Van Roy, Frans   +6 more
core   +2 more sources